Biology: Genetics and Cell Biology: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Genetics

Monohybrid cross (Aa × Aa)
genotypes 1 : 2 : 1, phenotypes 3 : 1
Dihybrid cross
phenotypes 9 : 3 : 3 : 1
Hardy–Weinberg
p + q = 1, p² + 2pq + q² = 1
Independent genes
multiply the probabilities

2Practice problems

1.GeneticsMedium
♂♀YXh​Xh​XH​

haemophilia is X-linked recessive (allele h). A carrier mother, XHXh, has children with an affected father, XhY. The mother's gametes run down the side. Click the cell for an unaffected son.

♀ XHXh♂ XhY
  1. 1Xh × Y
  2. 2Xh × Xh
  3. 3XH × Y
  4. 4XH × Xh
2.GeneticsHard
♂ AaBb♀ AaBbabaBABAbaBABabAb

Two AaBb parents are crossed. Gene A gives purple flowers (dominant) or white flowers; gene B gives round seeds (dominant) or wrinkled seeds. Click the one cell for an offspring that is shows both white flowers and wrinkled seeds.

AaBb × AaBb
  1. 1aB × ab
  2. 2aB × aB
  3. 3aB × AB
  4. 4aB × Ab
  5. 5AB × ab
  6. 6AB × aB
  7. 7AB × AB
  8. 8AB × Ab
  9. 9ab × ab
  10. 10ab × aB
  11. 11ab × AB
  12. 12ab × Ab
  13. 13Ab × ab
  14. 14Ab × aB
  15. 15Ab × AB
  16. 16Ab × Ab
3.Cell biologyMedium

How does glucose enter most body cells, such as red blood cells?

  1. ABy simple diffusion through the lipid bilayer
  2. BBy facilitated diffusion through GLUT carrier proteins
  3. CBy primary active transport using ATP directly at the membrane
  4. DBy phagocytosis
4.Cell biologyHard

Okazaki fragments are formed on:

  1. AtRNA during transcription
  2. BThe lagging strand during DNA replication
  3. CThe leading strand
  4. DmRNA during translation

3Solutions

1.Genetics

Answer: XH × Y

Punnett square: one parent's gametes run along the top, the other's down the side. Each cell joins the gamete above it with the gamete beside it, and every cell is equally likely. A recessive trait only shows when both alleles are recessive; for an X-linked trait, sons get their only X from the mother.

Fill the square

XhY, XhXh, XHY, XHXh

Find the cell

XH × Y = XHY

Answer

Cell XH × Y → XHY
2.Genetics

Answer: ab × ab

Punnett square: one parent's gametes run along the top, the other's down the side. Each cell joins the gamete above it with the gamete beside it, and every cell is equally likely. A recessive trait only shows when both alleles are recessive; for an X-linked trait, sons get their only X from the mother.

Genotype asked for

aabb

Gametes

A homozygous genotype needs the same gamete from both parents, so only one cell in the 16 fits.

ab × ab = aabb

Answer

Cell ab × ab → aabb
3.Cell biology

Answer: B · By facilitated diffusion through GLUT carrier proteins

Why this is the answer

Glucose uses GLUT carrier proteins to move down its concentration gradient without using ATP. This is facilitated diffusion.

Answer

B · By facilitated diffusion through GLUT carrier proteins
4.Cell biology

Answer: B · The lagging strand during DNA replication

Why this is the answer

The lagging strand is synthesised discontinuously in short fragments away from the fork, then joined by ligase.

Answer

B · The lagging strand during DNA replication

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