Biology: Genetics and Cell Biology: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Genetics

Monohybrid cross (Aa × Aa)
genotypes 1 : 2 : 1, phenotypes 3 : 1
Dihybrid cross
phenotypes 9 : 3 : 3 : 1
Hardy–Weinberg
p + q = 1, p² + 2pq + q² = 1
Independent genes
multiply the probabilities

2Practice problems

1.GeneticsMedium
AaBb ♀aaBb ♂ABAbaBabaBabaBab????????????????

Tall (A) is dominant over short (a), and round seeds (B) over wrinkled (b). The genes are on different chromosomes. For the cross AaBb × aaBb, what is the probability P that an offspring is tall, wrinkled seeds?

AaBb × aaBb
P =
2.GeneticsHard
♂ AaBb♀ AaBbaBAbabABABaBabAb

Two AaBb parents are crossed. Gene A gives tall plants (dominant) or short plants; gene B gives purple flowers (dominant) or white flowers. Click the one cell for an offspring that is shows short plants and is homozygous for purple flowers.

AaBb × AaBb
  1. 1AB × aB
  2. 2AB × Ab
  3. 3AB × ab
  4. 4AB × AB
  5. 5aB × aB
  6. 6aB × Ab
  7. 7aB × ab
  8. 8aB × AB
  9. 9ab × aB
  10. 10ab × Ab
  11. 11ab × ab
  12. 12ab × AB
  13. 13Ab × aB
  14. 14Ab × Ab
  15. 15Ab × ab
  16. 16Ab × AB
3.Cell biologyMedium

Active transport differs from facilitated diffusion because it:

  1. ANeeds no proteins
  2. BOnly moves water
  3. CMoves substances down their gradient faster by using carrier proteins
  4. DUses energy to move substances against their concentration gradient
4.Cell biologyHard

The endosymbiotic theory is supported by the fact that mitochondria:

  1. AContain chlorophyll
  2. BAre made in the nucleus
  3. CHave their own circular DNA and 70S-like ribosomes
  4. DHave no membranes

3Solutions

1.Genetics

Answer: P = 0.125

Mendelian genetics: each parent passes on one allele of each gene, chosen at random. A Punnett square lists every combination of gametes, each equally likely. A dominant allele (capital letter) shows whenever it is present; a recessive one only in the homozygous form. Genes on different chromosomes are inherited independently, so their probabilities multiply.

Each gene on its own

P(tall) = 0.5
P(wrinkled seeds) = 0.25

Multiply

P = 0.5·0.25 = 0.125

Answer

P = 0.125
2.Genetics

Answer: aB × aB

Punnett square: one parent's gametes run along the top, the other's down the side. Each cell joins the gamete above it with the gamete beside it, and every cell is equally likely. A recessive trait only shows when both alleles are recessive; for an X-linked trait, sons get their only X from the mother.

Genotype asked for

aaBB

Gametes

A homozygous genotype needs the same gamete from both parents, so only one cell in the 16 fits.

aB × aB = aaBB

Answer

Cell aB × aB → aaBB
3.Cell biology

Answer: D · Uses energy to move substances against their concentration gradient

Why this is the answer

Active transport uses ATP (or another gradient) to move molecules against their gradient; facilitated diffusion is passive.

Answer

D · Uses energy to move substances against their concentration gradient
4.Cell biology

Answer: C · Have their own circular DNA and 70S-like ribosomes

Why this is the answer

Mitochondria and chloroplasts have circular DNA, bacterial-like ribosomes, double membranes and divide by fission, suggesting a bacterial origin.

Answer

C · Have their own circular DNA and 70S-like ribosomes

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