Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
84 g/L1.8 g/kg/day60 mL/h69 kg20 h/day7 g/scoopn = ?

Practice exercise (made-up values, not clinical guidance). A 69 kg patient needs 1.8 g of protein per kg a day. The tube feed contains 84 g of protein per litre and runs at 60 mL/h for 20 hours a day. A protein powder supplies 7 g of protein per scoop. How many scoops n a day are needed to cover the shortfall? Round up to a whole scoop.

69 kg1.8 g/kg/day84 g/L60 mL/h · 20 h7 g/scoop
n =
2.Enteral & parenteral nutrition calculationsHard
24 hdextrose 12.5%1500 mLamino acids 6%1500 mLlipid 10%250 mL · 1.1 kcal/mLN = protein/6.25NPC : N = ? : 1

Practice exercise (made-up values, not clinical guidance). Over 24 hours a patient receives 1500 mL of parenteral nutrition with final concentrations of 12.5% dextrose and 6% amino acids, plus 250 mL of 10% lipid emulsion (1.1 kcal/mL). Find the non-protein kilocalorie to nitrogen ratio NPC : N (the number x in x : 1). Round to the nearest whole number.

1500 mLdextrose 12.5%amino acids 6%lipid 250 mL · 1.1 kcal/mL
NPC : N =
3.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftmilk240 mLsoup180 mLIV infusion50 mL/h × 8 hIV antibiotic1 × 50 mLurine400 mLurine425 mLurine400 mLurine500 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss).

milk: 240 mLsoup: 180 mLIV infusion: 50 mL/h × 8 hIV antibiotic: 1 × 50 mLurine: 400 mLurine: 425 mLurine: 400 mLurine: 500 mL
B = mL
4.IV fluids & fluid balanceHard
1000 mL350 mL infused75 mL/h06:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 75 mL/h. At 06:00, 350 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL350 mL infused75 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: n = 4

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Protein needed

1.8·69 = 124.2 g/day

Protein from the feed

60·20 = 1200 mL = 1.2 L
1.2·84 = 100.8 g/day

Shortfall

ΔP = 124.2 − 100.8 = 23.4 g

Scoops

23.4/7 = 3.343 → n = 4

Answer

n = 4
2.Enteral & parenteral nutrition calculations

Answer: NPC : N = 63

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Grams of dextrose and amino acids

dextrose: 12.5·1500/100 = 187.5 g
amino acids: 6·1500/100 = 90 g

Kilocalories per component

dextrose: 187.5·3.4 = 637.5 kcal
amino acids: 90·4 = 360 kcal
lipid: 250·1.1 = 275 kcal

Non-protein kcal and nitrogen

NPC = 637.5 + 275 = 912.5 kcal
N = 90/6.25 = 14.4 g

Ratio

NPC : N = 912.5/14.4 = 63.37 ≈ 63 : 1

Answer

NPC : N = 63

Ratios of about 150 : 1 are typical for stable patients; lower ratios give relatively more protein.

3.IV fluids & fluid balance

Answer: B = −855 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 240 + 180 = 420 mL
IV infusion: 50·8 = 400 mL
IV antibiotic: 1·50 = 50 mL
total intake = 870 mL

Total output

400 + 425 + 400 + 500 = 1725 mL

Balance

B = 870 − 1725 = −855 mL

Answer

B = −855 mL

Negative: the patient lost more fluid than went in.

4.IV fluids & fluid balance

Answer: t = 8.7 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 350 = 650 mL

Time

t = 650/75 = 8.667 ≈ 8.7 h

Answer

t = 8.7 h

That is about 8 h 40 min, so the bag runs out at about 14:40.

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