Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
1.2 kcal/mL81% free water75 mL/hevery 4 h73 kg · 30 mL/kg/day20 h/dayV = ? mL

Practice exercise (made-up values, not clinical guidance). A 73 kg patient has a fluid goal of 30 mL/kg/day and receives all fluid through a feeding tube. The formula is 81% free water and runs at 75 mL/h for 20 hours a day. The rest of the fluid is given as water flushes every 4 hours. What volume V is each flush? Round to the nearest whole number.

73 kg30 mL/kg/day81%75 mL/h · 20 hevery 4 h
V = mL
2.Enteral & parenteral nutrition calculationsHard
24 hdextrose 12.5%2400 mLamino acids 6%2400 mLlipid 20%250 mL · 2 kcal/mLdextrose 3.4 kcal/gamino acids 4 kcal/gE = ? kcal

Practice exercise (made-up values, not clinical guidance). Over 24 hours a patient receives 2400 mL of parenteral nutrition with final concentrations of 12.5% dextrose and 6% amino acids, plus 250 mL of 20% lipid emulsion (2 kcal/mL). Find the total energy E the patient receives in kcal per day. Round to the nearest whole number.

2400 mLdextrose 12.5%amino acids 6%lipid 250 mL · 2 kcal/mL
E = kcal/day
3.IV fluids & fluid balanceMedium
IntakeOutput12-hour shifttea240 mLmilk200 mLIV infusion125 mL/h × 12 hIV antibiotic1 × 50 mLurine500 mLurine350 mLvomit100 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL.

tea: 240 mLmilk: 200 mLIV infusion: 125 mL/h × 12 hIV antibiotic: 1 × 50 mL
I = mL
4.IV fluids & fluid balanceHard
1000 mL650 mL infused100 mL/h20:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 100 mL/h. At 20:00, 650 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL650 mL infused100 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: V = 163 mL

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Fluid goal

30·73 = 2190 mL/day

Free water from the formula

75·20 = 1500 mL
1500·0.81 = 1215 mL

Water still needed

2190 − 1215 = 975 mL/day

Volume per flush

24/4 = 6 flushes
V = 975/6 = 162.5 ≈ 163 mL

Answer

V = 163 mL
2.Enteral & parenteral nutrition calculations

Answer: E = 2096 kcal/day

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Grams of dextrose and amino acids

dextrose: 12.5·2400/100 = 300 g
amino acids: 6·2400/100 = 144 g

Kilocalories per component

dextrose: 300·3.4 = 1020 kcal
amino acids: 144·4 = 576 kcal
lipid: 250·2 = 500 kcal

Total energy

E = 1020 + 576 + 500 = 2096 kcal/day

Answer

E = 2096 kcal/day
3.IV fluids & fluid balance

Answer: I = 1990 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 240 + 200 = 440 mL
IV infusion: 125·12 = 1500 mL
IV antibiotic: 1·50 = 50 mL
I = 1990 mL

Answer

I = 1990 mL
4.IV fluids & fluid balance

Answer: t = 3.5 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 650 = 350 mL

Time

t = 350/100 = 3.5 h

Answer

t = 3.5 h

That is about 3 h 30 min, so the bag runs out at about 23:30.

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