Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
40 g/L1.8 g/kg/day80 mL/h63 kg20 h/dayΔP = ? g

Practice exercise (made-up values, not clinical guidance). A 63 kg patient needs 1.8 g of protein per kg a day. The tube feed contains 40 g of protein per litre and runs at 80 mL/h for 20 hours a day. How many grams of extra protein ΔP a day are still needed? Round to one decimal place.

63 kg1.8 g/kg/day40 g/L80 mL/h · 20 h
ΔP = g/day
2.Enteral & parenteral nutrition calculationsHard
24 hdextrose 10%2400 mLamino acids 3.5%2400 mLlipid 20%250 mL · 2 kcal/mLN = protein/6.25NPC : N = ? : 1

Practice exercise (made-up values, not clinical guidance). Over 24 hours a patient receives 2400 mL of parenteral nutrition with final concentrations of 10% dextrose and 3.5% amino acids, plus 250 mL of 20% lipid emulsion (2 kcal/mL). Find the non-protein kilocalorie to nitrogen ratio NPC : N (the number x in x : 1). Round to the nearest whole number.

2400 mLdextrose 10%amino acids 3.5%lipid 250 mL · 2 kcal/mL
NPC : N =
3.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftmilk100 mLwater240 mLice chips120 mLIV infusion80 mL/h × 12 hIV antibiotic2 × 100 mLurine375 mLurine425 mLwound drain70 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The patient weighs 56 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

56 kg12 hurine: 375 mLurine: 425 mLwound drain: 70 mL
U = mL/kg/h
4.IV fluids & fluid balanceHard
500 mL100 mL infused75 mL/h10:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 500 mL bag runs by pump at 75 mL/h. At 10:00, 100 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

500 mL100 mL infused75 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: ΔP = 49.4 g/day

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Protein needed

1.8·63 = 113.4 g/day

Protein from the feed

80·20 = 1600 mL = 1.6 L
1.6·40 = 64 g/day

Shortfall

ΔP = 113.4 − 64 = 49.4 g/day

Answer

ΔP = 49.4 g/day
2.Enteral & parenteral nutrition calculations

Answer: NPC : N = 98

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Grams of dextrose and amino acids

dextrose: 10·2400/100 = 240 g
amino acids: 3.5·2400/100 = 84 g

Kilocalories per component

dextrose: 240·3.4 = 816 kcal
amino acids: 84·4 = 336 kcal
lipid: 250·2 = 500 kcal

Non-protein kcal and nitrogen

NPC = 816 + 500 = 1316 kcal
N = 84/6.25 = 13.44 g

Ratio

NPC : N = 1316/13.44 = 97.92 ≈ 98 : 1

Answer

NPC : N = 98

Ratios of about 150 : 1 are typical for stable patients; lower ratios give relatively more protein.

3.IV fluids & fluid balance

Answer: U = 1.19 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

375 + 425 = 800 mL

Per kilogram per hour

U = 800/(56·12) = 1.19 mL/kg/h

Answer

U = 1.19 mL/kg/h
4.IV fluids & fluid balance

Answer: t = 5.3 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

500 − 100 = 400 mL

Time

t = 400/75 = 5.333 ≈ 5.3 h

Answer

t = 5.3 h

That is about 5 h 20 min, so the bag runs out at about 15:20.

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