Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
68 g/L1.5 g/kg/day90 mL/h90 kg18 h/day5 g/scoopn = ?

Practice exercise (made-up values, not clinical guidance). A 90 kg patient needs 1.5 g of protein per kg a day. The tube feed contains 68 g of protein per litre and runs at 90 mL/h for 18 hours a day. A protein powder supplies 5 g of protein per scoop. How many scoops n a day are needed to cover the shortfall? Round up to a whole scoop.

90 kg1.5 g/kg/day68 g/L90 mL/h · 18 h5 g/scoop
n =
2.Enteral & parenteral nutrition calculationsHard
12 hdextrose 12.5%1200 mLamino acids 6%1200 mL51 kg12 hGIR = ? mg/kg/min

Practice exercise (made-up values, not clinical guidance). A 51 kg adult receives 1200 mL of parenteral nutrition containing 12.5% dextrose, infused over 12 hours. Find the glucose infusion rate GIR in mg/kg/min. Round to two decimal places.

51 kg1200 mLdextrose 12.5%12 h
GIR = mg/kg/min
3.IV fluids & fluid balanceMedium
IntakeOutput12-hour shifttea240 mLmilk100 mLIV infusion60 mL/h × 12 hIV antibiotic1 × 100 mLurine275 mLurine400 mLurine375 mLwound drain90 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss).

tea: 240 mLmilk: 100 mLIV infusion: 60 mL/h × 12 hIV antibiotic: 1 × 100 mLurine: 275 mLurine: 400 mLurine: 375 mLwound drain: 90 mL
B = mL
4.IV fluids & fluid balanceHard
500 mL50 mL infused50 mL/h11:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 500 mL bag runs by pump at 50 mL/h. At 11:00, 50 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

500 mL50 mL infused50 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: n = 5

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Protein needed

1.5·90 = 135 g/day

Protein from the feed

90·18 = 1620 mL = 1.62 L
1.62·68 = 110.2 g/day

Shortfall

ΔP = 135 − 110.2 = 24.84 g

Scoops

24.84/5 = 4.968 → n = 5

Answer

n = 5
2.Enteral & parenteral nutrition calculations

Answer: GIR = 4.08 mg/kg/min

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Dextrose in the bag

12.5·1200/100 = 150 g = 150 000 mg

Minutes of infusion

12·60 = 720 min

Glucose infusion rate

GIR = 150 000/(51·720) = 4.085 ≈ 4.08 mg/kg/min

Answer

GIR = 4.08 mg/kg/min
3.IV fluids & fluid balance

Answer: B = 20 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 240 + 100 = 340 mL
IV infusion: 60·12 = 720 mL
IV antibiotic: 1·100 = 100 mL
total intake = 1160 mL

Total output

275 + 400 + 375 + 90 = 1140 mL

Balance

B = 1160 − 1140 = 20 mL

Answer

B = 20 mL

Positive: more fluid went in than came out.

4.IV fluids & fluid balance

Answer: t = 9 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

500 − 50 = 450 mL

Time

t = 450/50 = 9 h

Answer

t = 9 h

That is about 9 h 00 min, so the bag runs out at about 20:00.

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