Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
1 kcal/mL35 kcal/kg/day? mL/h80 kg24 h/day

Practice exercise (made-up values, not clinical guidance). An 80 kg adult (BMI below 30) needs 35 kcal/kg/day. The tube feed provides 1 kcal/mL and runs by pump for 24 hours a day. At what rate R do you set the pump, in mL/h? Round to the nearest whole number.

80 kg35 kcal/kg/day1 kcal/mL24 h
R = mL/h
2.Enteral & parenteral nutrition calculationsHard
24 hdextrose 10%2000 mLamino acids 3.5%2000 mLlipid 10%500 mL · 1.1 kcal/mLN = protein/6.25NPC : N = ? : 1

Practice exercise (made-up values, not clinical guidance). Over 24 hours a patient receives 2000 mL of parenteral nutrition with final concentrations of 10% dextrose and 3.5% amino acids, plus 500 mL of 10% lipid emulsion (1.1 kcal/mL). Find the non-protein kilocalorie to nitrogen ratio NPC : N (the number x in x : 1). Round to the nearest whole number.

2000 mLdextrose 10%amino acids 3.5%lipid 500 mL · 1.1 kcal/mL
NPC : N =
3.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftmilk240 mLjelly120 mLjuice200 mLIV infusion80 mL/h × 8 hIV antibiotic1 × 100 mLurine275 mLurine175 mLurine175 mLvomit200 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL.

milk: 240 mLjelly: 120 mLjuice: 200 mLIV infusion: 80 mL/h × 8 hIV antibiotic: 1 × 100 mL
I = mL
4.IV fluids & fluid balanceHard
1000 mL500 mL infused100 mL/h06:30t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 100 mL/h. At 06:30, 500 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL500 mL infused100 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: R = 117 mL/h

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Energy needed

E = 35·80 = 2800 kcal/day

Daily volume

V = 2800/1 = 2800 mL/day

Pump rate

R = 2800/24 = 116.7 ≈ 117 mL/h

Answer

R = 117 mL/h
2.Enteral & parenteral nutrition calculations

Answer: NPC : N = 110

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Grams of dextrose and amino acids

dextrose: 10·2000/100 = 200 g
amino acids: 3.5·2000/100 = 70 g

Kilocalories per component

dextrose: 200·3.4 = 680 kcal
amino acids: 70·4 = 280 kcal
lipid: 500·1.1 = 550 kcal

Non-protein kcal and nitrogen

NPC = 680 + 550 = 1230 kcal
N = 70/6.25 = 11.2 g

Ratio

NPC : N = 1230/11.2 = 109.8 ≈ 110 : 1

Answer

NPC : N = 110

Ratios of about 150 : 1 are typical for stable patients; lower ratios give relatively more protein.

3.IV fluids & fluid balance

Answer: I = 1300 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 240 + 120 + 200 = 560 mL
IV infusion: 80·8 = 640 mL
IV antibiotic: 1·100 = 100 mL
I = 1300 mL

Answer

I = 1300 mL
4.IV fluids & fluid balance

Answer: t = 5 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 500 = 500 mL

Time

t = 500/100 = 5 h

Answer

t = 5 h

That is about 5 h 00 min, so the bag runs out at about 11:30.

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