Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
55 g/L1.3 g/kg/day40 mL/h79 kg24 h/day10 g/scoopn = ?

Practice exercise (made-up values, not clinical guidance). A 79 kg patient needs 1.3 g of protein per kg a day. The tube feed contains 55 g of protein per litre and runs at 40 mL/h for 24 hours a day. A protein powder supplies 10 g of protein per scoop. How many scoops n a day are needed to cover the shortfall? Round up to a whole scoop.

79 kg1.3 g/kg/day55 g/L40 mL/h · 24 h10 g/scoop
n =
2.Enteral & parenteral nutrition calculationsHard
24 hdextrose 20%1000 mLamino acids 4%1000 mLlipid 20%250 mL · 2 kcal/mLdextrose 3.4 kcal/gamino acids 4 kcal/gNPC = ? kcal

Practice exercise (made-up values, not clinical guidance). Over 24 hours a patient receives 1000 mL of parenteral nutrition with final concentrations of 20% dextrose and 4% amino acids, plus 250 mL of 20% lipid emulsion (2 kcal/mL). Find the non-protein energy NPC in kcal per day. Round to the nearest whole number.

1000 mLdextrose 20%amino acids 4%lipid 250 mL · 2 kcal/mL
NPC = kcal/day
3.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftsoup180 mLjuice120 mLmilk240 mLIV infusion125 mL/h × 8 hIV antibiotic1 × 100 mLurine450 mLurine325 mLwound drain50 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss).

soup: 180 mLjuice: 120 mLmilk: 240 mLIV infusion: 125 mL/h × 8 hIV antibiotic: 1 × 100 mLurine: 450 mLurine: 325 mLwound drain: 50 mL
B = mL
4.IV fluids & fluid balanceHard
500 mL100 mL infused50 mL/h16:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 500 mL bag runs by pump at 50 mL/h. At 16:00, 100 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

500 mL100 mL infused50 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: n = 5

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Protein needed

1.3·79 = 102.7 g/day

Protein from the feed

40·24 = 960 mL = 0.96 L
0.96·55 = 52.8 g/day

Shortfall

ΔP = 102.7 − 52.8 = 49.9 g

Scoops

49.9/10 = 4.99 → n = 5

Answer

n = 5
2.Enteral & parenteral nutrition calculations

Answer: NPC = 1180 kcal/day

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Grams of dextrose and amino acids

dextrose: 20·1000/100 = 200 g
amino acids: 4·1000/100 = 40 g

Kilocalories per component

dextrose: 200·3.4 = 680 kcal
amino acids: 40·4 = 160 kcal
lipid: 250·2 = 500 kcal

Non-protein energy

NPC = 680 + 500 = 1180 kcal/day

Answer

NPC = 1180 kcal/day
3.IV fluids & fluid balance

Answer: B = 815 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 180 + 120 + 240 = 540 mL
IV infusion: 125·8 = 1000 mL
IV antibiotic: 1·100 = 100 mL
total intake = 1640 mL

Total output

450 + 325 + 50 = 825 mL

Balance

B = 1640 − 825 = 815 mL

Answer

B = 815 mL

Positive: more fluid went in than came out.

4.IV fluids & fluid balance

Answer: t = 8 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

500 − 100 = 400 mL

Time

t = 400/50 = 8 h

Answer

t = 8 h

That is about 8 h 00 min, so the bag runs out at about 00:00.

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