Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
1 kcal/mL84% free water90 mL/hevery 4 h86 kg · 30 mL/kg/day24 h/dayV = ? mL

Practice exercise (made-up values, not clinical guidance). An 86 kg patient has a fluid goal of 30 mL/kg/day and receives all fluid through a feeding tube. The formula is 84% free water and runs at 90 mL/h for 24 hours a day. The rest of the fluid is given as water flushes every 4 hours. What volume V is each flush? Round to the nearest whole number.

86 kg30 mL/kg/day84%90 mL/h · 24 hevery 4 h
V = mL
2.Enteral & parenteral nutrition calculationsHard
16 hdextrose 17.5%1000 mLamino acids 4.25%1000 mL51 kg16 hGIR = ? mg/kg/min

Practice exercise (made-up values, not clinical guidance). A 51 kg adult receives 1000 mL of parenteral nutrition containing 17.5% dextrose, infused over 16 hours. Find the glucose infusion rate GIR in mg/kg/min. Round to two decimal places.

51 kg1000 mLdextrose 17.5%16 h
GIR = mg/kg/min
3.IV fluids & fluid balanceMedium
IntakeOutput8-hour shifttea150 mLwater250 mLIV infusion100 mL/h × 8 hIV antibiotic1 × 50 mLurine200 mLurine200 mLurine325 mLurine225 mLvomit200 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss).

tea: 150 mLwater: 250 mLIV infusion: 100 mL/h × 8 hIV antibiotic: 1 × 50 mLurine: 200 mLurine: 200 mLurine: 325 mLurine: 225 mLvomit: 200 mL
B = mL
4.IV fluids & fluid balanceHard
500 mL200 mL infused80 mL/h10:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 500 mL bag runs by pump at 80 mL/h. At 10:00, 200 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

500 mL200 mL infused80 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: V = 128 mL

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Fluid goal

30·86 = 2580 mL/day

Free water from the formula

90·24 = 2160 mL
2160·0.84 = 1814 mL

Water still needed

2580 − 1814 = 765.6 mL/day

Volume per flush

24/4 = 6 flushes
V = 765.6/6 = 127.6 ≈ 128 mL

Answer

V = 128 mL
2.Enteral & parenteral nutrition calculations

Answer: GIR = 3.57 mg/kg/min

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Dextrose in the bag

17.5·1000/100 = 175 g = 175 000 mg

Minutes of infusion

16·60 = 960 min

Glucose infusion rate

GIR = 175 000/(51·960) = 3.574 ≈ 3.57 mg/kg/min

Answer

GIR = 3.57 mg/kg/min
3.IV fluids & fluid balance

Answer: B = 100 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 150 + 250 = 400 mL
IV infusion: 100·8 = 800 mL
IV antibiotic: 1·50 = 50 mL
total intake = 1250 mL

Total output

200 + 200 + 325 + 225 + 200 = 1150 mL

Balance

B = 1250 − 1150 = 100 mL

Answer

B = 100 mL

Positive: more fluid went in than came out.

4.IV fluids & fluid balance

Answer: t = 3.8 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

500 − 200 = 300 mL

Time

t = 300/80 = 3.75 ≈ 3.8 h

Answer

t = 3.8 h

That is about 3 h 45 min, so the bag runs out at about 13:45.

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