Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
1.5 kcal/mL76% free water90 mL/hevery 6 h94 kg · 30 mL/kg/day24 h/dayV = ? mL

Practice exercise (made-up values, not clinical guidance). A 94 kg patient has a fluid goal of 30 mL/kg/day and receives all fluid through a feeding tube. The formula is 76% free water and runs at 90 mL/h for 24 hours a day. The rest of the fluid is given as water flushes every 6 hours. What volume V is each flush? Round to the nearest whole number.

94 kg30 mL/kg/day76%90 mL/h · 24 hevery 6 h
V = mL
2.Enteral & parenteral nutrition calculationsHard
24 hdextrose 20%1800 mLamino acids 6%1800 mL51 kg24 hGIR = ? mg/kg/min

Practice exercise (made-up values, not clinical guidance). A 51 kg adult receives 1800 mL of parenteral nutrition containing 20% dextrose, infused over 24 hours. Find the glucose infusion rate GIR in mg/kg/min. Round to two decimal places.

51 kg1800 mLdextrose 20%24 h
GIR = mg/kg/min
3.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftwater200 mLmilk200 mLjuice120 mLIV infusion125 mL/h × 8 hIV antibiotic1 × 50 mLurine150 mLurine225 mLurine500 mLurine175 mLwound drain70 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss).

water: 200 mLmilk: 200 mLjuice: 120 mLIV infusion: 125 mL/h × 8 hIV antibiotic: 1 × 50 mLurine: 150 mLurine: 225 mLurine: 500 mLurine: 175 mLwound drain: 70 mL
B = mL
4.IV fluids & fluid balanceHard
500 mL→ 75 mL/hstart 08:00ttotal​ = ? h125 mL/h × 3 h

Practice exercise (made-up values, not clinical guidance). A 500 mL infusion starts at 08:00 at 125 mL/h. After 3 hours the rate is changed to 75 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

500 mL125 mL/h · 3 h75 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: V = 295 mL

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Fluid goal

30·94 = 2820 mL/day

Free water from the formula

90·24 = 2160 mL
2160·0.76 = 1642 mL

Water still needed

2820 − 1642 = 1178 mL/day

Volume per flush

24/6 = 4 flushes
V = 1178/4 = 294.6 ≈ 295 mL

Answer

V = 295 mL
2.Enteral & parenteral nutrition calculations

Answer: GIR = 4.9 mg/kg/min

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Dextrose in the bag

20·1800/100 = 360 g = 360 000 mg

Minutes of infusion

24·60 = 1440 min

Glucose infusion rate

GIR = 360 000/(51·1440) = 4.902 ≈ 4.9 mg/kg/min

Answer

GIR = 4.9 mg/kg/min
3.IV fluids & fluid balance

Answer: B = 450 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 200 + 200 + 120 = 520 mL
IV infusion: 125·8 = 1000 mL
IV antibiotic: 1·50 = 50 mL
total intake = 1570 mL

Total output

150 + 225 + 500 + 175 + 70 = 1120 mL

Balance

B = 1570 − 1120 = 450 mL

Answer

B = 450 mL

Positive: more fluid went in than came out.

4.IV fluids & fluid balance

Answer: t = 4.7 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

125·3 = 375 mL
500 − 375 = 125 mL left

Second part

125/75 = 1.667 h

Total time

t = 3 + 1.667 = 4.667 ≈ 4.7 h

Answer

t = 4.7 h

That is about 4 h 40 min, so the bag runs out at about 12:40.

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