Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
1 kcal/mL35 kcal/kg/day? mL/h64 kg16 h/day

Practice exercise (made-up values, not clinical guidance). A 64 kg adult (BMI below 30) needs 35 kcal/kg/day. The tube feed provides 1 kcal/mL and runs by pump for 16 hours a day. At what rate R do you set the pump, in mL/h? Round to the nearest whole number.

64 kg35 kcal/kg/day1 kcal/mL16 h
R = mL/h
2.Enteral & parenteral nutrition calculationsHard
24 hdextrose 15%1000 mLamino acids 3.5%1000 mLlipid 10%500 mL · 1.1 kcal/mLN = protein/6.25NPC : N = ? : 1

Practice exercise (made-up values, not clinical guidance). Over 24 hours a patient receives 1000 mL of parenteral nutrition with final concentrations of 15% dextrose and 3.5% amino acids, plus 500 mL of 10% lipid emulsion (1.1 kcal/mL). Find the non-protein kilocalorie to nitrogen ratio NPC : N (the number x in x : 1). Round to the nearest whole number.

1000 mLdextrose 15%amino acids 3.5%lipid 500 mL · 1.1 kcal/mL
NPC : N =
3.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftjuice120 mLjelly100 mLIV infusion60 mL/h × 8 hIV antibiotic1 × 50 mLurine225 mLurine375 mLurine350 mLurine500 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL.

juice: 120 mLjelly: 100 mLIV infusion: 60 mL/h × 8 hIV antibiotic: 1 × 50 mL
I = mL
4.IV fluids & fluid balanceHard
500 mL75 mL/hstart 09:3012:30: ? mL

Practice exercise (made-up values, not clinical guidance). A 500 mL bag was started at 09:30 and runs by pump at 75 mL/h. How many mL V are left in the bag at 12:30?

500 mL75 mL/h09:30 → 12:30
V = mL

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: R = 140 mL/h

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Energy needed

E = 35·64 = 2240 kcal/day

Daily volume

V = 2240/1 = 2240 mL/day

Pump rate

R = 2240/16 = 140 mL/h

Answer

R = 140 mL/h
2.Enteral & parenteral nutrition calculations

Answer: NPC : N = 189

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Grams of dextrose and amino acids

dextrose: 15·1000/100 = 150 g
amino acids: 3.5·1000/100 = 35 g

Kilocalories per component

dextrose: 150·3.4 = 510 kcal
amino acids: 35·4 = 140 kcal
lipid: 500·1.1 = 550 kcal

Non-protein kcal and nitrogen

NPC = 510 + 550 = 1060 kcal
N = 35/6.25 = 5.6 g

Ratio

NPC : N = 1060/5.6 = 189.3 ≈ 189 : 1

Answer

NPC : N = 189

Ratios of about 150 : 1 are typical for stable patients; lower ratios give relatively more protein.

3.IV fluids & fluid balance

Answer: I = 750 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 120 + 100 = 220 mL
IV infusion: 60·8 = 480 mL
IV antibiotic: 1·50 = 50 mL
I = 750 mL

Answer

I = 750 mL
4.IV fluids & fluid balance

Answer: V = 275 mL

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Elapsed time

09:30 → 12:30 = 3 h

Volume infused

75·3 = 225 mL

Volume left

V = 500 − 225 = 275 mL

Answer

V = 275 mL

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