Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
40 g/L1.3 g/kg/day40 mL/h66 kg20 h/dayΔP = ? g

Practice exercise (made-up values, not clinical guidance). A 66 kg patient needs 1.3 g of protein per kg a day. The tube feed contains 40 g of protein per litre and runs at 40 mL/h for 20 hours a day. How many grams of extra protein ΔP a day are still needed? Round to one decimal place.

66 kg1.3 g/kg/day40 g/L40 mL/h · 20 h
ΔP = g/day
2.Enteral & parenteral nutrition calculationsHard
24 hdextrose 25%2400 mLamino acids 5%2400 mLlipid 20%500 mL · 2 kcal/mLdextrose 3.4 kcal/gamino acids 4 kcal/gE = ? kcal

Practice exercise (made-up values, not clinical guidance). Over 24 hours a patient receives 2400 mL of parenteral nutrition with final concentrations of 25% dextrose and 5% amino acids, plus 500 mL of 20% lipid emulsion (2 kcal/mL). Find the total energy E the patient receives in kcal per day. Round to the nearest whole number.

2400 mLdextrose 25%amino acids 5%lipid 500 mL · 2 kcal/mL
E = kcal/day
3.IV fluids & fluid balanceMedium
IntakeOutput12-hour shifttea240 mLjuice100 mLIV infusion125 mL/h × 12 hIV antibiotic2 × 100 mLurine400 mLurine250 mLwound drain30 mLvomit200 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss).

tea: 240 mLjuice: 100 mLIV infusion: 125 mL/h × 12 hIV antibiotic: 2 × 100 mLurine: 400 mLurine: 250 mLwound drain: 30 mLvomit: 200 mL
B = mL
4.IV fluids & fluid balanceHard
1000 mL→ 80 mL/hstart 10:30ttotal​ = ? h120 mL/h × 4 h

Practice exercise (made-up values, not clinical guidance). A 1000 mL infusion starts at 10:30 at 120 mL/h. After 4 hours the rate is changed to 80 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

1000 mL120 mL/h · 4 h80 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: ΔP = 53.8 g/day

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Protein needed

1.3·66 = 85.8 g/day

Protein from the feed

40·20 = 800 mL = 0.8 L
0.8·40 = 32 g/day

Shortfall

ΔP = 85.8 − 32 = 53.8 g/day

Answer

ΔP = 53.8 g/day
2.Enteral & parenteral nutrition calculations

Answer: E = 3520 kcal/day

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Grams of dextrose and amino acids

dextrose: 25·2400/100 = 600 g
amino acids: 5·2400/100 = 120 g

Kilocalories per component

dextrose: 600·3.4 = 2040 kcal
amino acids: 120·4 = 480 kcal
lipid: 500·2 = 1000 kcal

Total energy

E = 2040 + 480 + 1000 = 3520 kcal/day

Answer

E = 3520 kcal/day
3.IV fluids & fluid balance

Answer: B = 1160 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 240 + 100 = 340 mL
IV infusion: 125·12 = 1500 mL
IV antibiotic: 2·100 = 200 mL
total intake = 2040 mL

Total output

400 + 250 + 30 + 200 = 880 mL

Balance

B = 2040 − 880 = 1160 mL

Answer

B = 1160 mL

Positive: more fluid went in than came out.

4.IV fluids & fluid balance

Answer: t = 10.5 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

120·4 = 480 mL
1000 − 480 = 520 mL left

Second part

520/80 = 6.5 h

Total time

t = 4 + 6.5 = 10.5 h

Answer

t = 10.5 h

That is about 10 h 30 min, so the bag runs out at about 21:00.

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