Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
40 g/L1.2 g/kg/day70 mL/h76 kg16 h/dayΔP = ? g

Practice exercise (made-up values, not clinical guidance). A 76 kg patient needs 1.2 g of protein per kg a day. The tube feed contains 40 g of protein per litre and runs at 70 mL/h for 16 hours a day. How many grams of extra protein ΔP a day are still needed? Round to one decimal place.

76 kg1.2 g/kg/day40 g/L70 mL/h · 16 h
ΔP = g/day
2.Enteral & parenteral nutrition calculationsHard
14 kgdextrose 7.5%50 mL/hGIR = ? mg/kg/min

Practice exercise (made-up values, not clinical guidance). A child who weighs 14 kg receives 7.5% dextrose at 50 mL/h. Find the glucose infusion rate GIR in mg/kg/min. Round to two decimal places.

14 kg7.5%50 mL/h
GIR = mg/kg/min
3.IV fluids & fluid balanceMedium
IntakeOutput12-hour shifttea240 mLjuice120 mLmilk100 mLIV infusion50 mL/h × 12 hIV antibiotic1 × 100 mLurine375 mLurine450 mLurine350 mLurine500 mLwound drain130 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL.

tea: 240 mLjuice: 120 mLmilk: 100 mLIV infusion: 50 mL/h × 12 hIV antibiotic: 1 × 100 mL
I = mL
4.IV fluids & fluid balanceHard
500 mL200 mL infused80 mL/h10:30t = ? h

Practice exercise (made-up values, not clinical guidance). A 500 mL bag runs by pump at 80 mL/h. At 10:30, 200 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

500 mL200 mL infused80 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: ΔP = 46.4 g/day

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Protein needed

1.2·76 = 91.2 g/day

Protein from the feed

70·16 = 1120 mL = 1.12 L
1.12·40 = 44.8 g/day

Shortfall

ΔP = 91.2 − 44.8 = 46.4 g/day

Answer

ΔP = 46.4 g/day
2.Enteral & parenteral nutrition calculations

Answer: GIR = 4.46 mg/kg/min

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Dextrose concentration

7.5% = 75 mg/mL

Dextrose per minute

75·50/60 = 62.5 mg/min

Per kilogram

GIR = 62.5/14 = 4.464 ≈ 4.46 mg/kg/min

Answer

GIR = 4.46 mg/kg/min

Shortcut: GIR = % dextrose × mL/h/(6 × kg).

3.IV fluids & fluid balance

Answer: I = 1160 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 240 + 120 + 100 = 460 mL
IV infusion: 50·12 = 600 mL
IV antibiotic: 1·100 = 100 mL
I = 1160 mL

Answer

I = 1160 mL
4.IV fluids & fluid balance

Answer: t = 3.8 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

500 − 200 = 300 mL

Time

t = 300/80 = 3.75 ≈ 3.8 h

Answer

t = 3.8 h

That is about 3 h 45 min, so the bag runs out at about 14:15.

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