Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
84 g/L2 g/kg/day40 mL/h51 kg16 h/dayΔP = ? g

Practice exercise (made-up values, not clinical guidance). A 51 kg patient needs 2 g of protein per kg a day. The tube feed contains 84 g of protein per litre and runs at 40 mL/h for 16 hours a day. How many grams of extra protein ΔP a day are still needed? Round to one decimal place.

51 kg2 g/kg/day84 g/L40 mL/h · 16 h
ΔP = g/day
2.Enteral & parenteral nutrition calculationsHard
24 hdextrose 25%1000 mLamino acids 5%1000 mLlipid 10%500 mL · 1.1 kcal/mLN = protein/6.25NPC : N = ? : 1

Practice exercise (made-up values, not clinical guidance). Over 24 hours a patient receives 1000 mL of parenteral nutrition with final concentrations of 25% dextrose and 5% amino acids, plus 500 mL of 10% lipid emulsion (1.1 kcal/mL). Find the non-protein kilocalorie to nitrogen ratio NPC : N (the number x in x : 1). Round to the nearest whole number.

1000 mLdextrose 25%amino acids 5%lipid 500 mL · 1.1 kcal/mL
NPC : N =
3.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftsoup200 mLtea200 mLjuice150 mLice chips100 mLIV infusion75 mL/h × 12 hIV antibiotic1 × 100 mLurine225 mLurine475 mLurine200 mLwound drain90 mLvomit250 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The patient weighs 86 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

86 kg12 hurine: 225 mLurine: 475 mLurine: 200 mLwound drain: 90 mLvomit: 250 mL
U = mL/kg/h
4.IV fluids & fluid balanceHard
500 mL50 mL infused75 mL/h16:30t = ? h

Practice exercise (made-up values, not clinical guidance). A 500 mL bag runs by pump at 75 mL/h. At 16:30, 50 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

500 mL50 mL infused75 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: ΔP = 48.2 g/day

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Protein needed

2·51 = 102 g/day

Protein from the feed

40·16 = 640 mL = 0.64 L
0.64·84 = 53.76 g/day

Shortfall

ΔP = 102 − 53.76 = 48.24 ≈ 48.2 g/day

Answer

ΔP = 48.2 g/day
2.Enteral & parenteral nutrition calculations

Answer: NPC : N = 175

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Grams of dextrose and amino acids

dextrose: 25·1000/100 = 250 g
amino acids: 5·1000/100 = 50 g

Kilocalories per component

dextrose: 250·3.4 = 850 kcal
amino acids: 50·4 = 200 kcal
lipid: 500·1.1 = 550 kcal

Non-protein kcal and nitrogen

NPC = 850 + 550 = 1400 kcal
N = 50/6.25 = 8 g

Ratio

NPC : N = 1400/8 = 175 : 1

Answer

NPC : N = 175

Ratios of about 150 : 1 are typical for stable patients; lower ratios give relatively more protein.

3.IV fluids & fluid balance

Answer: U = 0.87 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

225 + 475 + 200 = 900 mL

Per kilogram per hour

U = 900/(86·12) = 0.8721 ≈ 0.87 mL/kg/h

Answer

U = 0.87 mL/kg/h
4.IV fluids & fluid balance

Answer: t = 6 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

500 − 50 = 450 mL

Time

t = 450/75 = 6 h

Answer

t = 6 h

That is about 6 h 00 min, so the bag runs out at about 22:30.

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