Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
63 g/L1.2 g/kg/day75 mL/h88 kg16 h/dayΔP = ? g

Practice exercise (made-up values, not clinical guidance). An 88 kg patient needs 1.2 g of protein per kg a day. The tube feed contains 63 g of protein per litre and runs at 75 mL/h for 16 hours a day. How many grams of extra protein ΔP a day are still needed? Round to one decimal place.

88 kg1.2 g/kg/day63 g/L75 mL/h · 16 h
ΔP = g/day
2.Enteral & parenteral nutrition calculationsHard
24 hdextrose 15%2000 mLamino acids 4.25%2000 mLlipid 10%500 mL · 1.1 kcal/mLdextrose 3.4 kcal/gamino acids 4 kcal/gE = ? kcal

Practice exercise (made-up values, not clinical guidance). Over 24 hours a patient receives 2000 mL of parenteral nutrition with final concentrations of 15% dextrose and 4.25% amino acids, plus 500 mL of 10% lipid emulsion (1.1 kcal/mL). Find the total energy E the patient receives in kcal per day. Round to the nearest whole number.

2000 mLdextrose 15%amino acids 4.25%lipid 500 mL · 1.1 kcal/mL
E = kcal/day
3.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftjuice100 mLmilk200 mLice chips100 mLIV infusion80 mL/h × 12 hIV antibiotic2 × 100 mLurine225 mLurine175 mLurine150 mLurine200 mLwound drain60 mLvomit100 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The patient weighs 94 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

94 kg12 hurine: 225 mLurine: 175 mLurine: 150 mLurine: 200 mLwound drain: 60 mLvomit: 100 mL
U = mL/kg/h
4.IV fluids & fluid balanceHard
500 mL100 mL/hstart 09:0011:30: ? mL

Practice exercise (made-up values, not clinical guidance). A 500 mL bag was started at 09:00 and runs by pump at 100 mL/h. How many mL V are left in the bag at 11:30?

500 mL100 mL/h09:00 → 11:30
V = mL

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: ΔP = 30 g/day

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Protein needed

1.2·88 = 105.6 g/day

Protein from the feed

75·16 = 1200 mL = 1.2 L
1.2·63 = 75.6 g/day

Shortfall

ΔP = 105.6 − 75.6 = 30 g/day

Answer

ΔP = 30 g/day
2.Enteral & parenteral nutrition calculations

Answer: E = 1910 kcal/day

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Grams of dextrose and amino acids

dextrose: 15·2000/100 = 300 g
amino acids: 4.25·2000/100 = 85 g

Kilocalories per component

dextrose: 300·3.4 = 1020 kcal
amino acids: 85·4 = 340 kcal
lipid: 500·1.1 = 550 kcal

Total energy

E = 1020 + 340 + 550 = 1910 kcal/day

Answer

E = 1910 kcal/day
3.IV fluids & fluid balance

Answer: U = 0.66 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

225 + 175 + 150 + 200 = 750 mL

Per kilogram per hour

U = 750/(94·12) = 0.6649 ≈ 0.66 mL/kg/h

Answer

U = 0.66 mL/kg/h
4.IV fluids & fluid balance

Answer: V = 250 mL

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Elapsed time

09:00 → 11:30 = 2.5 h

Volume infused

100·2.5 = 250 mL

Volume left

V = 500 − 250 = 250 mL

Answer

V = 250 mL

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