Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
1.5 kcal/mL76% free water50 mL/hevery 4 h66 kg · 35 mL/kg/day24 h/dayV = ? mL

Practice exercise (made-up values, not clinical guidance). A 66 kg patient has a fluid goal of 35 mL/kg/day and receives all fluid through a feeding tube. The formula is 76% free water and runs at 50 mL/h for 24 hours a day. The rest of the fluid is given as water flushes every 4 hours. What volume V is each flush? Round to the nearest whole number.

66 kg35 mL/kg/day76%50 mL/h · 24 hevery 4 h
V = mL
2.Enteral & parenteral nutrition calculationsHard
24 hdextrose 25%1000 mLamino acids 3.5%1000 mL83 kg24 hGIR = ? mg/kg/min

Practice exercise (made-up values, not clinical guidance). An 83 kg adult receives 1000 mL of parenteral nutrition containing 25% dextrose, infused over 24 hours. Find the glucose infusion rate GIR in mg/kg/min. Round to two decimal places.

83 kg1000 mLdextrose 25%24 h
GIR = mg/kg/min
3.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftjelly100 mLtea150 mLIV infusion100 mL/h × 12 hIV antibiotic1 × 50 mLurine450 mLurine475 mLurine400 mLurine450 mLvomit100 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL.

jelly: 100 mLtea: 150 mLIV infusion: 100 mL/h × 12 hIV antibiotic: 1 × 50 mL
I = mL
4.IV fluids & fluid balanceHard
500 mL→ 200 mL/hstart 15:30ttotal​ = ? h125 mL/h × 2 h

Practice exercise (made-up values, not clinical guidance). A 500 mL infusion starts at 15:30 at 125 mL/h. After 2 hours the rate is changed to 200 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

500 mL125 mL/h · 2 h200 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: V = 233 mL

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Fluid goal

35·66 = 2310 mL/day

Free water from the formula

50·24 = 1200 mL
1200·0.76 = 912 mL

Water still needed

2310 − 912 = 1398 mL/day

Volume per flush

24/4 = 6 flushes
V = 1398/6 = 233 mL

Answer

V = 233 mL
2.Enteral & parenteral nutrition calculations

Answer: GIR = 2.09 mg/kg/min

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Dextrose in the bag

25·1000/100 = 250 g = 250 000 mg

Minutes of infusion

24·60 = 1440 min

Glucose infusion rate

GIR = 250 000/(83·1440) = 2.092 ≈ 2.09 mg/kg/min

Answer

GIR = 2.09 mg/kg/min
3.IV fluids & fluid balance

Answer: I = 1500 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 100 + 150 = 250 mL
IV infusion: 100·12 = 1200 mL
IV antibiotic: 1·50 = 50 mL
I = 1500 mL

Answer

I = 1500 mL
4.IV fluids & fluid balance

Answer: t = 3.3 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

125·2 = 250 mL
500 − 250 = 250 mL left

Second part

250/200 = 1.25 h

Total time

t = 2 + 1.25 = 3.25 ≈ 3.3 h

Answer

t = 3.3 h

That is about 3 h 15 min, so the bag runs out at about 18:45.

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