A newborn's bilirubin is rising quickly at 30 hours despite phototherapy, and the baby is lethargic with an arched back and high-pitched cry. What does this suggest?
AMild breast milk jaundice
BA normal reaction to phototherapy
CAcute bilirubin encephalopathy
DNormal newborn reflexes
3.Dosage calculationsMedium
A patient weighing 120 kg has a body surface area of 2.09 m². The prescription is 135 mg/m². Find the dose D in mg.
120 kgBSA = 2.09 m²135 mg/m²
D = mg
4.Dosage calculationsHard
A patient is 141 cm tall and weighs 38 kg. The prescription is 250 mg/m². Using the Mosteller formula BSA = √(height (cm) × weight (kg)/3600), find the dose D in mg.
141 cm38 kg250 mg/m²
D = mg
5.IV infusion ratesMedium
Infuse 250 mL over 4 hours with a giving set of 60 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.
250 mL4 h60 gtt/mL
R = gtt/min
6.IV infusion ratesHard
A drip runs at 20 gtt/min through a set of 20 gtt/mL. There are 450 mL left in the bag. How many hours t until it is empty?
20 gtt/min20 gtt/mL450 mL
t = h
3Solutions
1.Maternity & obstetric nursing
Answer: D · At 34 weeks: severe headache, BP 164/110 mmHg
Why this is the answer
Severe-range blood pressure with a headache suggests pre-eclampsia with severe features and a risk of eclampsia or stroke. The other women are stable.
Answer
D · At 34 weeks: severe headache, BP 164/110 mmHg
2.Maternity & obstetric nursing
Answer: C · Acute bilirubin encephalopathy
Why this is the answer
Lethargy, poor feeding, hypertonia with arching and a high-pitched cry are signs of acute bilirubin encephalopathy. An urgent exchange transfusion may be needed to prevent permanent kernicterus.
Answer
C · Acute bilirubin encephalopathy
3.Dosage calculations
Answer: D = 282.1 mg
Body-surface-area dosing: many cytotoxic and some paediatric doses are prescribed per square metre of body surface area: dose (mg) = dose per m² × BSA (m²). The Mosteller formula estimates BSA = √(height (cm) × weight (kg)/3600).
Dose
D = 135·2.09 = 282.1 mg
Answer
D = 282.1 mg
4.Dosage calculations
Answer: D = 305 mg
Body-surface-area dosing: many cytotoxic and some paediatric doses are prescribed per square metre of body surface area: dose (mg) = dose per m² × BSA (m²). The Mosteller formula estimates BSA = √(height (cm) × weight (kg)/3600).
Body surface area
BSA = √(141·38/3600) = √1.488 = 1.22 m²
Dose
D = 250·1.22 = 305 mg
Answer
D = 305 mg
5.IV infusion rates
Answer: R = 63 gtt/min
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
Time in minutes
4·60 = 240 min
Drip rate
R = 250·60/240 = 62.5 ≈ 63 gtt/min
Answer
R = 63 gtt/min
At the bedside you round to the nearest whole drop: 63 gtt/min.
6.IV infusion rates
Answer: t = 7.5 h
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.