A pregnant woman involved in a car crash asks how to wear a seat belt. Which instruction is correct?
ALap belt under the bump, shoulder belt between the breasts
BDo not wear a seat belt in pregnancy
CWear only the shoulder part of the belt
DPut the lap belt across the top of the bump, above the uterus
3.Dosage calculationsMedium
A dose of 100 mg is needed from a 2% (w/v) solution. What volume V contains this dose?
100 mg2% w/v
V = mL
4.Dosage calculationsHard
A patient weighs 35.2 lb. The prescription is 5 mg/kg as a single dose, and the stock contains 250 mg in 5 mL. Using 1 kg = 2.2 lb, what volume V do you give?
35.2 lb5 mg/kg250 mg/5 mL1 kg = 2.2 lb
V = mL
5.IV infusion ratesMedium
Infuse 1000 mL over 8 hours with a giving set of 10 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.
1000 mL8 h10 gtt/mL
R = gtt/min
6.IV infusion ratesHard
An infusion of 50 mg in 500 mL runs at 3 mL/h. How many micrograms per minute D does the patient receive?
50 mg/500 mL3 mL/h
D = mcg/min
3Solutions
1.Maternity & obstetric nursing
Answer: D · At 34 weeks: severe headache, BP 164/110 mmHg
Why this is the answer
Severe-range blood pressure with a headache suggests pre-eclampsia with severe features and a risk of eclampsia or stroke. The other women are stable.
Answer
D · At 34 weeks: severe headache, BP 164/110 mmHg
2.Maternity & obstetric nursing
Answer: A · Lap belt under the bump, shoulder belt between the breasts
Why this is the answer
The lap belt should sit low under the abdomen across the hips and thighs, with the shoulder belt across the chest and to the side of the bump. Wearing a seat belt greatly reduces maternal and fetal injury.
Answer
A · Lap belt under the bump, shoulder belt between the breasts
3.Dosage calculations
Answer: V = 5 mL
Solution strengths: a percentage strength is grams per 100 mL, so 1% = 1 g/100 mL = 10 mg/mL. A ratio strength 1:1000 means 1 g in 1000 mL = 1 mg/mL; 1:10 000 is 0.1 mg/mL. For a dilution the amount of drug stays the same: C₁·V₁ = C₂·V₂.
Concentration
2% = 20 mg/mL
Volume
V = 100/20 = 5 mL
Answer
V = 5 mL
4.Dosage calculations
Answer: V = 1.6 mL
Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.
Weight in kg
35.2/2.2 = 16 kg
Dose
5·16 = 80 mg
Volume
V = (80/250)·5 = 1.6 mL
Answer
V = 1.6 mL
5.IV infusion rates
Answer: R = 21 gtt/min
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
Time in minutes
8·60 = 480 min
Drip rate
R = 1000·10/480 = 20.83 ≈ 21 gtt/min
Answer
R = 21 gtt/min
At the bedside you round to the nearest whole drop: 21 gtt/min.
6.IV infusion rates
Answer: D = 5 mcg/min
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).