One hour after a vaginal birth, the fundus is firm at the umbilicus, but there is a steady trickle of bright red blood. What is the most likely cause?
AA tear of the cervix, vagina or perineum
BA full bladder
CNormal lochia rubra
DUterine atony with blood pooling in the uterus
3.Dosage calculationsMedium
A vial contains 2 g of powder. The label says: add 7.4 mL of water for injection to give a total volume of 8 mL. The prescription is 250 mg. What volume V of the reconstituted solution do you give?
2 g+ 7.4 mL → 8 mL250 mg
V = mL
4.Dosage calculationsHard
The prescription is 300 units of a drug that comes as 1000 units/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?
300 units1000 units/mL
V = mL
5.IV infusion ratesMedium
1500 mL was ordered over 6 hours. After 4 hours you find that 640 mL is still in the bag, and the order must still finish on time. To what rate R in mL/h must the pump be reset?
1500 mL / 6 hafter 4 h: 640 mL
R = mL/h
6.IV infusion ratesHard
100 mg of a drug is diluted in 100 mL and given by gravity through a set of 60 gtt/mL. The order is 40 mg per hour. Find the drip rate R in drops per minute.
100 mg/100 mL40 mg/h60 gtt/mL
R = gtt/min
3Solutions
1.Maternity & obstetric nursing
Answer: A · Haemolysis, elevated liver enzymes, low platelets
Why this is the answer
HELLP syndrome is a serious complication of pre-eclampsia. Right upper quadrant or epigastric pain, nausea and malaise are typical, and blood pressure is not always very high.
Answer
A · Haemolysis, elevated liver enzymes, low platelets
2.Maternity & obstetric nursing
Answer: A · A tear of the cervix, vagina or perineum
Why this is the answer
Continuous bright red bleeding with a firm uterus suggests trauma (laceration), which needs inspection and repair. Atony would make the uterus soft, and normal lochia does not flow in a steady stream.
Answer
A · A tear of the cervix, vagina or perineum
3.Dosage calculations
Answer: V = 1 mL
Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.
Concentration after mixing
2000 mg/8 mL = 250 mg/mL
Volume
V = 250/250 = 1 mL
Answer
V = 1 mL
4.Dosage calculations
Answer: V = 0.3 mL
Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.
Volume
V = 300/1000 = 0.3 mL
On the syringe
On this 1 mL syringe every small line is 0.01 mL.
Answer
V = 0.3 mL
5.IV infusion rates
Answer: R = 320 mL/h
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
Original rate
1500/6 = 250 mL/h
New rate
R = 640/2 = 320 mL/h
Answer
R = 320 mL/h
This is more than a 25% increase: most hospitals require you to contact the prescriber instead of catching up, and to assess the patient for fluid overload.
6.IV infusion rates
Answer: R = 40 gtt/min
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).