Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient is starting warfarin for a DVT. Why is heparin or LMWH also given for the first several days?
ABoth drugs must always be continued together for life
BHeparin improves the absorption of warfarin
CWarfarin takes several days to reach its full effect
DHeparin protects against bleeding from warfarin
2.Med-surg: cardiovascular & respiratoryHard
After a car crash, a patient is severely breathless with absent breath sounds on the right, a deviated trachea, distended neck veins and BP 76/40 mmHg. What is the immediate management?
AA chest X-ray to confirm the diagnosis before any treatment
BInsertion of a urinary catheter to monitor output
CUrgent needle or finger decompression of the right chest
DLying the patient flat with the legs raised
3.Med-surg: neuro, endocrine & renalMedium
Why are patients with an acute spinal cord injury at high risk of deep vein thrombosis?
AParalysed leg muscles no longer pump blood back to the heart
BSpinal injuries always damage the large veins of the legs
CThe injury makes the blood too thin to clot properly in the veins
DThey usually take oestrogen as part of their treatment
4.Med-surg: neuro, endocrine & renalHard
A patient with a stroke and right-sided weakness is ready to transfer from bed to chair. Which approach is safest?
APlace the chair on the left side and pivot towards it
BPull the patient up by the right shoulder and wrist
CPlace the chair on the right and lift by the weak arm
DAsk the patient to stand alone and walk to the chair
5.Med-surg: GI, perioperative & oncologyMedium
Which infection control measure is correct for a patient with C. difficile diarrhoea?
AA face mask for the patient and visitors only
BA single room with its own toilet, and soap-and-water handwashing
CA shared bay, as long as alcohol gel is used after every contact
DNo special measures once antibiotics have started
6.Med-surg: GI, perioperative & oncologyHard
Which new prescription for a patient with cirrhosis should the nurse question?
ASpironolactone for ascites
BThiamine supplements
CRegular ibuprofen for back pain
DLactulose to keep the bowels open
7.Clinical nursingMedium
How should a nurse communicate with a patient who has impaired hearing?
ASpeak very quickly to save time
BShout loudly from the end of the bed so they can hear
CFace the patient, speak clearly and reduce background noise
DTalk to the patient's relative instead of to the patient directly
8.Clinical nursingHard
A postoperative patient has a heart rate of 115/min, temperature 38.6 °C, respiratory rate 26/min and blood pressure 85/50 mmHg despite a fluid bolus. What does this most likely indicate?
AMild dehydration only
BA normal inflammatory response in the first days after surgery
CAnxiety about discharge
DSeptic shock requiring urgent critical care review
9.Lab values & electrolytesMedium
In chronic kidney disease, a high serum phosphate is usually accompanied by which change in calcium?
AA low serum calcium
BA high serum calcium
CA high serum potassium only, with no calcium change
DNo change in calcium
10.Lab values & electrolytesHard
The nurse teaches a patient with thrombocytopenia (platelets 25 × 10³/µL) about home safety. Which statement shows a need for further teaching?
A"I'll blow my nose gently, not forcefully"
B"I'll use a soft-bristled toothbrush"
C"I'll use an electric razor to shave"
D"I'll take aspirin if I get a headache"
11.Arterial blood gas interpretationMedium
Practice values: Na⁺ 141 mmol/L, glucose 8.5 mmol/L and urea 20.2 mmol/L. Calculate the serum osmolality Osm = 2·Na⁺ + glucose + urea to the nearest whole number.
Na⁺ 141 mmol/Lglucose 8.5 mmol/Lurea 20.2 mmol/L
Osm = mOsm/kg
12.Arterial blood gas interpretationHard
A practice gas shows a respiratory acidosis: pH 7.19, PaCO₂ 76 mmHg (10.1 kPa), HCO₃⁻ 28 mmol/L. Use the rules ‘HCO₃⁻ rises 1 mmol/L per 10 mmHg (acute) or 3.5 mmol/L per 10 mmHg (chronic)’ to classify it. Click your answer.
pH 7.19PaCO₂ 76 mmHg (10.1 kPa)HCO₃⁻ 28 mmol/L
1acute
2chronic
3acute on chronic
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial fibrillation
2atrial flutter, 4:1 conduction
3junctional rhythm
4atrial flutter, 2:1 conduction
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1first-degree AV block
2second-degree AV block type I (Wenckebach)
3third-degree (complete) AV block
4second-degree AV block type II
15.Prioritization & delegationMedium
A nursing assistant tells the RN that a patient’s IV pump is alarming. What is the best response?
A“I will come and check the pump and the IV site now.”
B“Increase the rate a little so the alarm clears.”
C“Silence the alarm and I will check it at the end of the shift.”
D“Turn the pump off and on again until it stops.”
16.Prioritization & delegationHard
Four laboratory results come back at once. Which one should the nurse report first?
APotassium 3.4 mEq/L in a patient on a diuretic
BHemoglobin 6.5 g/dL (65 g/L) in a patient with a GI bleed
CGlucose 180 mg/dL after a meal in a patient with diabetes
DCreatinine 1.3 mg/dL in an older adult, unchanged from last week
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · Warfarin takes several days to reach its full effect
Why this is the answer
Warfarin reduces synthesis of vitamin K-dependent clotting factors, but existing factors take days to clear, and early on it can briefly increase clotting tendency. Heparin or LMWH is overlapped for at least five days and until the INR has been in range (usually ≥2) for at least 24 hours.
Answer
C · Warfarin takes several days to reach its full effect
2.Med-surg: cardiovascular & respiratory
Answer: C · Urgent needle or finger decompression of the right chest
Why this is the answer
These signs indicate a tension pneumothorax, which causes obstructive shock. It is decompressed immediately (needle or finger thoracostomy) without waiting for an X-ray, followed by a chest drain. The nurse gives high-flow oxygen and calls for senior help.
Answer
C · Urgent needle or finger decompression of the right chest
3.Med-surg: neuro, endocrine & renal
Answer: A · Paralysed leg muscles no longer pump blood back to the heart
Why this is the answer
Paralysis removes the calf muscle pump, and immobility causes venous stasis. Trauma also makes the blood more likely to clot. Prophylaxis usually combines anticoagulation and mechanical methods when safe.
Answer
A · Paralysed leg muscles no longer pump blood back to the heart
4.Med-surg: neuro, endocrine & renal
Answer: A · Place the chair on the left side and pivot towards it
Why this is the answer
Transfers are safer towards the stronger side, so the patient can bear weight and pivot on the good leg. Pulling on a weak arm can cause shoulder subluxation and pain. Physiotherapy advice and appropriate aids should be followed.
Answer
A · Place the chair on the left side and pivot towards it
5.Med-surg: GI, perioperative & oncology
Answer: B · A single room with its own toilet, and soap-and-water handwashing
Why this is the answer
C. difficile forms spores that resist alcohol gel, so soap and water are used. Patients are isolated with their own toilet, staff use gloves and aprons, and the environment is cleaned with a sporicidal agent such as chlorine.
Answer
B · A single room with its own toilet, and soap-and-water handwashing
6.Med-surg: GI, perioperative & oncology
Answer: C · Regular ibuprofen for back pain
Why this is the answer
NSAIDs can cause kidney injury, fluid retention and GI bleeding in cirrhosis and should be avoided. Paracetamol at a reduced, carefully reviewed dose is usually preferred for pain.
Answer
C · Regular ibuprofen for back pain
7.Clinical nursing
Answer: C · Face the patient, speak clearly and reduce background noise
Why this is the answer
Facing the patient in good light, speaking clearly at a normal pace, checking hearing aids and reducing noise improves communication. Written information can also help.
Answer
C · Face the patient, speak clearly and reduce background noise
8.Clinical nursing
Answer: D · Septic shock requiring urgent critical care review
Why this is the answer
Infection signs with hypotension not responding to fluid suggest septic shock. Vasopressors and critical care input are likely needed, along with antibiotics and source control.
Answer
D · Septic shock requiring urgent critical care review
9.Lab values & electrolytes
Answer: A · A low serum calcium
Why this is the answer
When failing kidneys retain phosphate, phosphate binds calcium and vitamin D activation falls, so serum calcium tends to drop. This drives secondary hyperparathyroidism and bone disease.
Answer
A · A low serum calcium
10.Lab values & electrolytes
Answer: D · "I'll take aspirin if I get a headache"
Why this is the answer
Aspirin irreversibly inhibits platelet function and raises the bleeding risk further in thrombocytopenia, so it and other NSAIDs are avoided unless prescribed. An electric razor, gentle nose blowing and a soft toothbrush reduce minor bleeding.
Answer
D · "I'll take aspirin if I get a headache"
11.Arterial blood gas interpretation
Answer: Osm = 311 mOsm/kg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Calculated osmolality
Osm = 2·141 + 8.5 + 20.2 = 310.7 ≈ 311 mOsm/kg
Answer
Osm = 311 mOsm/kg
12.Arterial blood gas interpretation
Answer: acute
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected HCO₃⁻
acute: 24 + 1·3.6 = 27.6 mmol/L
chronic: 24 + 3.5·3.6 = 36.6 mmol/L
Compare
measured: 28 mmol/L → acute
Answer
acute
13.ECG rhythm strip interpretation
Answer: atrial fibrillation
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: 8 QRS complexes in 6 s, × 10 = 80 per minute.
2. Rhythm: irregularly irregular, R–R from 0.58 to 1.04 s with no pattern.
3. P waves: none; the baseline shows small irregular fibrillatory waves.
4. PR interval: not measurable.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
atrial fibrillation
Answer
atrial fibrillation
14.ECG rhythm strip interpretation
Answer: second-degree AV block type I (Wenckebach)
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: 4 QRS complexes in 6 s, × 10 = 40 per minute.
2. Rhythm: regularly irregular, the QRS complexes come in groups separated by a pause (group beating).
3. P waves: upright and regular (P–P 0.96 s, 63 per minute); one P in every 4 is not followed by a QRS.
4. PR interval: lengthens 0.16 → 0.28 → 0.34 s, then a P wave is not conducted.
5. QRS: 0.06 s, narrow (below 0.12 s).
Interpretation
second-degree AV block type I (Wenckebach)
Answer
second-degree AV block type I (Wenckebach)
15.Prioritization & delegation
Answer: A · “I will come and check the pump and the IV site now.”
Why this is the answer
An alarm may mean an occlusion, air in the line or infiltration. The nurse checks the pump and site; the assistant should not adjust the pump or silence alarms.
Answer
A · “I will come and check the pump and the IV site now.”
16.Prioritization & delegation
Answer: B · Hemoglobin 6.5 g/dL (65 g/L) in a patient with a GI bleed
Why this is the answer
A hemoglobin of 6.5 g/dL (65 g/L) in a bleeding patient shows severe anemia and may need urgent transfusion. The other results are mildly abnormal or stable.
Answer
B · Hemoglobin 6.5 g/dL (65 g/L) in a patient with a GI bleed