Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Why is a beta-blocker started at a low dose and increased slowly in heart failure?
AIt can briefly worsen symptoms before long-term benefit appears
BIt works only if the dose is never changed after the first day
CIt must be stopped as soon as symptoms improve
DIt is safe only at the highest possible dose from the very start
2.Med-surg: cardiovascular & respiratoryHard
A patient with heart failure on a 1.5 L/day fluid restriction complains of severe thirst. Which measure is most appropriate?
ANo fluids at all until the next morning's weight
BMouth care, counted ice chips and fluids spread through the day
CUnlimited water, because thirst must always be satisfied
DSalty snacks to stimulate saliva and relieve dryness
3.Med-surg: neuro, endocrine & renalMedium
Which statement about the PSA blood test is correct?
AA normal result always rules out any prostate cancer
BIt can be raised by benign problems as well as by cancer
CIt is only raised in women with bladder cancer
DA raised result always means prostate cancer
4.Med-surg: neuro, endocrine & renalHard
A haemodialysis patient missed their last two sessions. They are breathless, with crackles, and the potassium is 6.9 mmol/L. What is the priority?
ALarge IV fluid boluses to improve the circulation
BA routine dialysis session at the next planned slot
CUrgent dialysis, with cardiac monitoring meanwhile
DOral potassium supplements and rest
5.Med-surg: GI, perioperative & oncologyMedium
Which task for a stable patient with an established ileostomy can usually be delegated to a trained healthcare assistant (nursing assistant)?
AEmptying the pouch and measuring the output
BTeaching the patient about high-output risks
CDeciding whether IV fluids are needed
DAssessing the stoma for signs of necrosis
6.Med-surg: GI, perioperative & oncologyHard
During burn resuscitation, a 70 kg adult's urine output has been 120 mL/h for 3 hours, and the face and limbs are very oedematous. What should the nurse do?
AIncrease the fluid rate to keep the output high
BGive a diuretic without discussing it
CStop all IV fluids completely and remove the catheter
DDiscuss reducing the fluid rate with the team
7.Clinical nursingMedium
What is one advantage of a direct oral anticoagulant (DOAC) such as apixaban compared with warfarin?
AIt has no risk of bleeding
BIt is safe in all patients with severe kidney failure
CIt never interacts with other drugs
DIt does not need routine INR monitoring
8.Clinical nursingHard
A nurse is teaching a patient who is starting warfarin. Which statement shows a need for further teaching?
A"I can take aspirin if I get a headache."
B"I will report black stools or unusual bruising."
C"I will keep my INR blood test appointments."
D"I will tell my dentist that I take warfarin."
9.Lab values & electrolytesMedium
Why do patients with chronic kidney disease often have anemia?
AHigh potassium in kidney disease breaks down red cells
BThe kidneys make less erythropoietin, which drives red cell production
CThe damaged kidneys filter out and destroy red blood cells
DUremic toxins make the bone marrow produce white cells instead of red cells
10.Lab values & electrolytesHard
A patient on long-term amiodarone has fatigue and weight gain. TSH is 11 mIU/L and the free T4 is low. What is the most likely explanation?
AAmiodarone-induced hyperthyroidism
BA normal response to amiodarone needing no action
CAmiodarone-induced hypothyroidism
DSecondary hypothyroidism from pituitary failure
11.Arterial blood gas interpretationMedium
Practice values: Na⁺ 146 mmol/L, glucose 31.3 mmol/L and urea 19.3 mmol/L. Calculate the serum osmolality Osm = 2·Na⁺ + glucose + urea to the nearest whole number.
Na⁺ 146 mmol/Lglucose 31.3 mmol/Lurea 19.3 mmol/L
Osm = mOsm/kg
12.Arterial blood gas interpretationHard
A practice gas shows a respiratory acidosis: pH 7.27, PaCO₂ 70 mmHg (9.3 kPa), HCO₃⁻ 31 mmol/L. Use the rules ‘HCO₃⁻ rises 1 mmol/L per 10 mmHg (acute) or 3.5 mmol/L per 10 mmHg (chronic)’ to classify it. Click your answer.
pH 7.27PaCO₂ 70 mmHg (9.3 kPa)HCO₃⁻ 31 mmol/L
1acute
2chronic
3acute on chronic
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial flutter, 3:1 conduction
2atrial fibrillation
3atrial flutter, 4:1 conduction
4sinus tachycardia
14.ECG rhythm strip interpretationHard
Interpret this lead II strip with the five steps in order: rate, rhythm, P waves, PR interval, QRS duration. At which step do you find the first abnormal finding? Click it.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1rate
2rhythm
3P waves
4PR interval
5QRS duration
15.Prioritization & delegationMedium
A patient receiving chemotherapy has a temperature of 38.3 °C and a very low neutrophil count. What should the nurse do?
AGive a cool shower and offer extra fluids, then wait and see what happens
BRecheck the temperature in four hours before telling anyone
CReport it at once, because cultures and antibiotics are needed quickly
DDocument the reading and mention it at the next handover
16.Prioritization & delegationHard
A medical-unit nurse is floated to intensive care and given a patient on a ventilator, which the nurse has never managed. What is the best response?
AAccept the full assignment without comment to avoid conflict
BLeave the intensive care unit and go back to the medical unit without telling anyone
CTell the charge nurse about the gap, accept tasks within competence and ask for support
DRefuse to work and go home, because the assignment is unsafe
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · It can briefly worsen symptoms before long-term benefit appears
Why this is the answer
Beta-blockers improve survival in heart failure with reduced ejection fraction, but they can cause tiredness, low blood pressure, bradycardia and fluid retention when first started. They are therefore started low and increased gradually in stable patients, with monitoring of weight, pulse and BP.
Answer
A · It can briefly worsen symptoms before long-term benefit appears
2.Med-surg: cardiovascular & respiratory
Answer: B · Mouth care, counted ice chips and fluids spread through the day
Why this is the answer
Spreading fluids through the day, using small cups, sucking ice chips (counted in the total), sugar-free gum and regular mouth care help patients tolerate fluid restriction. Salty foods increase thirst and fluid retention.
Answer
B · Mouth care, counted ice chips and fluids spread through the day
3.Med-surg: neuro, endocrine & renal
Answer: B · It can be raised by benign problems as well as by cancer
Why this is the answer
PSA can rise with BPH, prostatitis, UTI, recent ejaculation or instrumentation, as well as cancer. A normal level does not exclude cancer. Results are interpreted with symptoms, examination and other tests.
Answer
B · It can be raised by benign problems as well as by cancer
4.Med-surg: neuro, endocrine & renal
Answer: C · Urgent dialysis, with cardiac monitoring meanwhile
Why this is the answer
Missing dialysis causes fluid overload and hyperkalaemia, both of which can be fatal. The patient needs cardiac monitoring, emergency treatment of the potassium and urgent dialysis to remove fluid and potassium.
Answer
C · Urgent dialysis, with cardiac monitoring meanwhile
5.Med-surg: GI, perioperative & oncology
Answer: A · Emptying the pouch and measuring the output
Why this is the answer
Emptying and measuring output is a routine task. Assessment of the stoma, teaching and decisions about treatment remain with the registered nurse, who reviews the recorded output.
Answer
A · Emptying the pouch and measuring the output
6.Med-surg: GI, perioperative & oncology
Answer: D · Discuss reducing the fluid rate with the team
Why this is the answer
An output of about 1.7 mL/kg/h suggests over-resuscitation. Excess fluid ("fluid creep") worsens oedema and can cause pulmonary oedema and compartment syndromes, so the rate is reviewed and reduced under the burn protocol.
Answer
D · Discuss reducing the fluid rate with the team
7.Clinical nursing
Answer: D · It does not need routine INR monitoring
Why this is the answer
DOACs have predictable effects so INR monitoring is not needed. They still cause bleeding, have some interactions and need kidney function checked.
Answer
D · It does not need routine INR monitoring
8.Clinical nursing
Answer: A · "I can take aspirin if I get a headache."
Why this is the answer
Aspirin and other NSAIDs increase the bleeding risk with warfarin, so patients should ask before taking any new medicine. Paracetamol (acetaminophen) is usually the safer choice for simple pain.
Answer
A · "I can take aspirin if I get a headache."
9.Lab values & electrolytes
Answer: B · The kidneys make less erythropoietin, which drives red cell production
Why this is the answer
Diseased kidneys produce less erythropoietin, so the marrow makes fewer red cells. Treatment can include erythropoiesis-stimulating agents and iron.Checked against:Anemia · MedlinePlus (NIH) (2026); Erythropoietin test · MedlinePlus (NIH) (2025)
Answer
B · The kidneys make less erythropoietin, which drives red cell production
10.Lab values & electrolytes
Answer: C · Amiodarone-induced hypothyroidism
Why this is the answer
Amiodarone is rich in iodine and can cause either hypothyroidism or hyperthyroidism. A high TSH with a low free T4 shows primary hypothyroidism, so thyroid function is monitored before and during therapy; liver tests are monitored too.Checked against:Hypothyroidism · MedlinePlus (NIH) (2024)
Answer
C · Amiodarone-induced hypothyroidism
11.Arterial blood gas interpretation
Answer: Osm = 343 mOsm/kg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Calculated osmolality
Osm = 2·146 + 31.3 + 19.3 = 342.6 ≈ 343 mOsm/kg
Answer
Osm = 343 mOsm/kg
12.Arterial blood gas interpretation
Answer: acute on chronic
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected HCO₃⁻
acute: 24 + 1·3 = 27 mmol/L
chronic: 24 + 3.5·3 = 34.5 mmol/L
Compare
measured: 31 mmol/L → acute on chronic
Answer
acute on chronic
13.ECG rhythm strip interpretation
Answer: atrial flutter, 4:1 conduction
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 20 small boxes, 1500 ÷ 20 ≈ 75 per minute.
2. Rhythm: regular, every R–R is 0.80 s.
3. P waves: none; regular sawtooth flutter waves every 0.20 s (300 per minute), 4 for each QRS.
4. PR interval: not measurable.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
atrial flutter, 4:1 conduction
Answer
atrial flutter, 4:1 conduction
14.ECG rhythm strip interpretation
Answer: rhythm
Five steps for every strip: 1. rate (300 or 1500 method, or the 6-second method if irregular); 2. rhythm: are the R–R intervals equal; 3. P waves: present, upright in lead II, one before every QRS and all alike; 4. PR interval: 0.12–0.20 s and constant; 5. QRS duration: below 0.12 s. Only after the five steps name the rhythm. Normal sinus rhythm passes all five: 60–100/min, regular, upright P before every QRS, PR 0.12–0.20 s, QRS below 0.12 s.
Five steps
1. Rate: 8 QRS complexes in 6 s, × 10 = 80 per minute.
2. Rhythm: irregularly irregular, R–R from 0.64 to 0.94 s with no pattern.
3. P waves: none; the baseline shows small irregular fibrillatory waves.
4. PR interval: not measurable.
5. QRS: 0.08 s, narrow (below 0.12 s).
First abnormal step
rhythm → atrial fibrillation
Answer
rhythm
15.Prioritization & delegation
Answer: C · Report it at once, because cultures and antibiotics are needed quickly
Why this is the answer
Neutropenic fever is a medical emergency. The patient may have few other signs of infection, so the nurse reports it immediately so that cultures can be taken and IV antibiotics started.
Answer
C · Report it at once, because cultures and antibiotics are needed quickly
16.Prioritization & delegation
Answer: C · Tell the charge nurse about the gap, accept tasks within competence and ask for support
Why this is the answer
A nurse should clearly state the limits of their competence and ask for an assignment or support that keeps patients safe. Leaving without handover would be patient abandonment.
Answer
C · Tell the charge nurse about the gap, accept tasks within competence and ask for support