Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Which finding shows that long-standing hypertension has caused target organ damage?
AA heart rate of 72/min
BClear lung fields on the chest X-ray
CA normal fasting glucose
DLeft ventricular hypertrophy on the ECG
2.Med-surg: cardiovascular & respiratoryHard
A patient with rheumatoid arthritis is due to start an anti-TNF biologic drug. Which screening is essential beforehand?
AAn exercise ECG test on a treadmill
BA peak flow diary for a month
CA sweat chloride test
DScreening for latent tuberculosis
3.Med-surg: neuro, endocrine & renalMedium
A patient on peritoneal dialysis has gained weight and has higher glucose levels. Which part of the treatment is the likely cause?
AProtein lost into the dialysis fluid
BGlucose absorbed from the dialysis fluid
CSodium lost into the dialysis fluid
DAir entering the abdomen during exchanges
4.Med-surg: neuro, endocrine & renalHard
During a water deprivation test for suspected diabetes insipidus, the patient loses more than 3% of body weight and becomes hypotensive. What should the nurse do?
AGive the patient a large drink and then restart the test
BGive desmopressin without a prescription
CContinue the test, because this result is expected
DStop the test and inform the doctor
5.Med-surg: GI, perioperative & oncologyMedium
A patient received IV morphine 20 minutes ago and the surgical consent form has not been signed. What should the nurse do?
AAsk a relative to sign instead of the patient
BAsk the patient to sign quickly before they get sleepier
CSign the form on the patient's behalf as a witness
DTell the surgeon, as the patient may not be able to consent now
6.Med-surg: GI, perioperative & oncologyHard
A patient with small bowel obstruction has a nasogastric tube draining 2 L a day. Which nursing focus is most important?
AAccurate fluid balance with IV replacement and electrolyte checks
BRemoving the tube once 1 L has drained to prevent losses
CClamping the tube for long periods to save the stomach fluid
DGiving oral fluids freely to replace what the tube removes
7.Clinical nursingMedium
After a laparoscopic cholecystectomy, a patient has pain in the shoulder tip. What is the most likely cause?
AA broken collarbone from being moved onto the table
BA heart attack caused by the stress of surgery
CAn allergic reaction to the dressing
DGas used during the operation irritating the diaphragm
8.Clinical nursingHard
Which sign is often a late finding in hypovolaemic shock in a young, previously fit adult?
AA slightly raised respiratory rate
BA fall in blood pressure
CA rise in heart rate
DCool peripheries
9.Lab values & electrolytesMedium
A patient takes high-dose biotin supplements for hair and nails. Why should the nurse report this before blood tests?
ABiotin causes a true rise in blood glucose in all patients
BBiotin lowers the hemoglobin by destroying the red cells
CBiotin can distort some immunoassays, such as troponin or TSH
DBiotin makes the blood clot in the tube before testing
10.Lab values & electrolytesHard
A patient on a thiazide diuretic has a sodium of 129 mEq/L, a potassium of 3.2 mEq/L and feels weak. Which explanation fits best?
AThe patient is overhydrated from IV fluids only
BThe patient has primary hyperaldosteronism with high sodium
CThe diuretic is causing sodium and potassium loss
DThe results are typical of kidney failure
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.37, PaCO₂ 57 mmHg (7.6 kPa) and HCO₃⁻ 32 mmol/L. The primary disorder is respiratory acidosis. How far is it compensated? Click your answer.
pH 7.37PaCO₂ 57 mmHg (7.6 kPa)HCO₃⁻ 32 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
At sea level, a practice gas taken on 50% oxygen shows PaO₂ 86 mmHg (11.5 kPa) and PaCO₂ 30 mmHg (4.0 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1first-degree AV block
2sinus tachycardia
3normal sinus rhythm
4junctional rhythm
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1second-degree AV block type II
2third-degree (complete) AV block
3sinus bradycardia
4first-degree AV block
15.Prioritization & delegationMedium
A woman calls to say her husband suddenly has a drooping face and slurred speech. What should the nurse advise?
ALet him lie down and see if it improves
BBook an appointment with his doctor next week
CCall emergency services now and note the time it started
DDrive him to the hospital yourself after he has eaten dinner
16.Prioritization & delegationHard
After a cervical spinal cord injury, a patient has a blood pressure of 80/50 mmHg, a heart rate of 48/min and warm, dry skin. What is most likely?
ANeurogenic shock
BHypovolemic shock
CSeptic shock
DCardiac tamponade
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · Left ventricular hypertrophy on the ECG
Why this is the answer
Target organ damage from hypertension includes left ventricular hypertrophy, retinopathy, chronic kidney disease with proteinuria, and stroke. Its presence changes treatment urgency and targets.
Answer
D · Left ventricular hypertrophy on the ECG
2.Med-surg: cardiovascular & respiratory
Answer: D · Screening for latent tuberculosis
Why this is the answer
TNF-alpha is essential for containing TB in granulomas. Anti-TNF drugs can reactivate latent TB, sometimes as severe disseminated disease. Patients are screened (history, chest X-ray, IGRA) and treated for latent TB before starting.
Answer
D · Screening for latent tuberculosis
3.Med-surg: neuro, endocrine & renal
Answer: B · Glucose absorbed from the dialysis fluid
Why this is the answer
Standard PD fluids contain glucose to pull water out by osmosis. Some glucose is absorbed, adding calories and raising blood glucose. Glucose monitoring and diet advice are needed, and other solutions may be used.
Answer
B · Glucose absorbed from the dialysis fluid
4.Med-surg: neuro, endocrine & renal
Answer: D · Stop the test and inform the doctor
Why this is the answer
In DI, the patient keeps passing dilute urine despite fluid restriction and can become dangerously dehydrated. Significant weight loss, hypotension or a high sodium are reasons to stop the test and get medical review.
Answer
D · Stop the test and inform the doctor
5.Med-surg: GI, perioperative & oncology
Answer: D · Tell the surgeon, as the patient may not be able to consent now
Why this is the answer
Opioids and sedatives can impair understanding, so consent may not be valid. The surgeon is informed; consent is obtained when the patient has capacity, or other legal processes are followed in an emergency.
Answer
D · Tell the surgeon, as the patient may not be able to consent now
6.Med-surg: GI, perioperative & oncology
Answer: A · Accurate fluid balance with IV replacement and electrolyte checks
Why this is the answer
Large NG losses cause dehydration, hypokalaemia and a hypochloraemic metabolic alkalosis. The aspirate is measured and recorded, replaced IV as prescribed (often with potassium-containing crystalloid), and urea, creatinine and electrolytes are checked at least daily. Oral fluids would increase the losses and vomiting risk.
Answer
A · Accurate fluid balance with IV replacement and electrolyte checks
7.Clinical nursing
Answer: D · Gas used during the operation irritating the diaphragm
Why this is the answer
Carbon dioxide used to inflate the abdomen can irritate the diaphragm, causing referred shoulder-tip pain. It usually settles within a few days with mobilisation and analgesia.
Answer
D · Gas used during the operation irritating the diaphragm
8.Clinical nursing
Answer: B · A fall in blood pressure
Why this is the answer
Young adults compensate for blood loss with tachycardia and vasoconstriction, so blood pressure may stay normal until a large volume is lost. Hypotension is therefore a late and serious sign.
Answer
B · A fall in blood pressure
9.Lab values & electrolytes
Answer: C · Biotin can distort some immunoassays, such as troponin or TSH
Why this is the answer
Many immunoassays use biotin-streptavidin binding, and high blood biotin levels can give falsely high or low results, for example a falsely low troponin or abnormal thyroid tests. The laboratory and prescriber should know about biotin use.
Answer
C · Biotin can distort some immunoassays, such as troponin or TSH
10.Lab values & electrolytes
Answer: C · The diuretic is causing sodium and potassium loss
Why this is the answer
Thiazide diuretics commonly cause hyponatremia and hypokalemia, especially in older adults. The nurse reports the results, and the prescriber reviews the drug and electrolyte replacement.
Answer
C · The diuretic is causing sodium and potassium loss
11.Arterial blood gas interpretation
Answer: fully compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.37: within 7.35–7.45
PaCO₂ 57 mmHg: high (35–45)
HCO₃⁻ 32 mmol/L: high (22–26)
Compensation
fully compensated
Answer
fully compensated
12.Arterial blood gas interpretation
Answer: A–a gradient = 233 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Alveolar oxygen
PAO₂ = 0.5·713 − 30/0.8 = 356.5 − 37.5 = 319 mmHg
Gradient
A–a = 319 − 86 = 233 mmHg
Answer
A–a gradient = 233 mmHg
13.ECG rhythm strip interpretation
Answer: first-degree AV block
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 22 small boxes, 1500 ÷ 22 ≈ 68 per minute.
2. Rhythm: regular, every R–R is 0.88 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.34 s, constant, longer than 0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
first-degree AV block
Answer
first-degree AV block
14.ECG rhythm strip interpretation
Answer: second-degree AV block type II
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: 5 QRS complexes in 6 s, × 10 = 50 per minute.
2. Rhythm: the P waves are regular; R–R is regular except for a long pause where a QRS is missing.
3. P waves: upright and regular (P–P 0.80 s, 75 per minute); one P in every 3 is not followed by a QRS.
4. PR interval: constant at 0.16 s in the conducted beats.
5. QRS: 0.14 s, wide (0.12 s or more).
Interpretation
second-degree AV block type II
Answer
second-degree AV block type II
Type II and third-degree blocks are the ones that can suddenly progress, so textbooks rank them as more serious than type I.
15.Prioritization & delegation
Answer: C · Call emergency services now and note the time it started
Why this is the answer
Stroke is time-critical. Emergency services can begin assessment on the way and take the patient to a stroke center; the time of onset guides treatment.
Answer
C · Call emergency services now and note the time it started
16.Prioritization & delegation
Answer: A · Neurogenic shock
Why this is the answer
Neurogenic shock follows loss of sympathetic tone, causing vasodilation, hypotension and bradycardia with warm skin. Hypovolemic shock usually causes a fast pulse and cool, clammy skin.