Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient has had atrial fibrillation for more than 48 hours and is listed for elective cardioversion. Why is anticoagulation needed beforehand?
AAnticoagulants convert AF back to sinus rhythm
BAnticoagulants make the shock less painful
CAtrial clots may be dislodged when sinus rhythm returns
DAnticoagulants reduce the electrical energy needed for the shock
2.Med-surg: cardiovascular & respiratoryHard
Why is the cuff pressure of an endotracheal or tracheostomy tube checked regularly?
AThe cuff pressure directly controls the patient's oxygen saturation
BThe cuff must be kept fully deflated in every ventilated patient
CToo high a pressure damages the trachea; too low allows aspiration
DThe cuff pressure sets the ventilator's breathing rate
3.Med-surg: neuro, endocrine & renalMedium
What is the main purpose of continuous bladder irrigation after a transurethral resection of the prostate (TURP)?
ATo give the patient extra fluids
BTo treat a urinary infection after the operation
CTo measure the size of the bladder
DTo stop blood clots from blocking the catheter
4.Med-surg: neuro, endocrine & renalHard
A patient taking an SGLT2 inhibitor is booked for major surgery. Which statement is correct?
AThe drug must be taken right up until the operation starts
BThe dose is usually doubled on the morning of surgery
CIt is usually paused in the days before surgery
DSurgery is not possible in patients taking this drug
5.Med-surg: GI, perioperative & oncologyMedium
Why are antiemetics usually given before chemotherapy starts?
APreventing nausea works better than treating it later
BThey stop the chemotherapy from causing hair loss and mouth sores
CAntiemetics make the chemotherapy work better
DThey cannot be given once nausea has started
6.Med-surg: GI, perioperative & oncologyHard
Using the adult rule of nines, what is the total burn area of the whole right arm plus the whole front of the trunk (both with partial-thickness burns)?
A36%
B27%
C45%
D18%
7.Clinical nursingMedium
A nurse suspects that an older patient is being financially abused by a relative. What should the nurse do?
AKeep it secret because it is a family matter
BRaise the concern through the local safeguarding (adult protection) procedure
CWait until the patient has been discharged
DConfront the relative directly at the bedside about it
8.Clinical nursingHard
Why can sepsis be missed in older adults?
AOlder adults cannot develop sepsis because their immune system is weaker
BBlood tests are not useful in older people
COlder adults always have a very high fever
DThey may have no fever and present with confusion, falls or reduced mobility
9.Lab values & electrolytesMedium
A patient's potassium is unexpectedly 5.8 mEq/L. The sample was taken after the tourniquet was on for several minutes while the patient pumped their fist. What is the best interpretation?
AFist pumping lowers potassium, so the true level is even higher
BTourniquet time affects only the glucose result, not the potassium
CThe result confirms true hyperkalemia and needs no further checking
DThe result may be falsely high and should be repeated with better technique
10.Lab values & electrolytesHard
A patient has a continuous heparin infusion for a pulmonary embolism. A new nurse plans to adjust the infusion using today's INR of 1.1. What should the experienced nurse explain?
AThe INR is the correct test, and 1.1 means heparin is therapeutic
BHeparin needs no laboratory monitoring once the infusion is started
CHeparin is adjusted using the aPTT or anti-Xa level, not the INR
DThe INR of 1.1 means the heparin rate must be doubled at once
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 18 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 18 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.11, PaCO₂ 39 mmHg (5.2 kPa), HCO₃⁻ 12 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.11PaCO₂ 39 mmHg (5.2 kPa)HCO₃⁻ 12 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
Measure the QT interval on this lead II strip, in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QT = s
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1torsades de pointes
2supraventricular tachycardia (SVT)
3ventricular fibrillation
4idioventricular rhythm
15.Prioritization & delegationMedium
A drowsy patient has an arterial blood gas with pH 7.30, PaCO₂ 58 mmHg (7.7 kPa) and HCO₃⁻ 25 mEq/L (mmol/L). Which problem is the priority?
ALoss of bicarbonate from the bowel through severe diarrhea
BPoor ventilation causing carbon dioxide to build up
CHyperventilation caused by anxiety
DToo much bicarbonate from antacids
16.Prioritization & delegationHard
Four stable patients need routine morning care. To reduce the spread of infection, which patient should the nurse visit first?
AA patient with an MRSA wound infection
BA patient with influenza on droplet precautions
CA patient with C. difficile diarrhea
DA patient with neutropenia after chemotherapy
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · Atrial clots may be dislodged when sinus rhythm returns
Why this is the answer
After 48 hours of AF, atrial thrombus may be present. Restoring organised contraction can expel it and cause a stroke. Patients are usually anticoagulated for at least three weeks before (or a transoesophageal echo excludes clot) and for at least four weeks afterwards.
Answer
C · Atrial clots may be dislodged when sinus rhythm returns
2.Med-surg: cardiovascular & respiratory
Answer: C · Too high a pressure damages the trachea; too low allows aspiration
Why this is the answer
Cuff pressure is usually kept at about 20–30 cmH₂O. Higher pressures reduce blood flow to the tracheal mucosa, risking ulceration and stenosis; lower pressures allow secretions to leak past and cause aspiration and VAP. A cuff manometer is used.
Answer
C · Too high a pressure damages the trachea; too low allows aspiration
3.Med-surg: neuro, endocrine & renal
Answer: D · To stop blood clots from blocking the catheter
Why this is the answer
After TURP, the raw prostate bed bleeds, and clots can block the catheter and cause retention and bladder spasms. Continuous irrigation through a three-way catheter keeps the drainage flowing.
Answer
D · To stop blood clots from blocking the catheter
4.Med-surg: neuro, endocrine & renal
Answer: C · It is usually paused in the days before surgery
Why this is the answer
Fasting, surgery and dehydration increase the risk of euglycaemic DKA with SGLT2 inhibitors. Guidance usually advises stopping them in the days before major surgery and restarting when the patient is eating and drinking normally.
Answer
C · It is usually paused in the days before surgery
5.Med-surg: GI, perioperative & oncology
Answer: A · Preventing nausea works better than treating it later
Why this is the answer
Chemotherapy-induced nausea and vomiting is better prevented than treated. Antiemetics are given before treatment and regularly afterwards, according to how emetogenic the regimen is.
Answer
A · Preventing nausea works better than treating it later
6.Med-surg: GI, perioperative & oncology
Answer: B · 27%
Why this is the answer
The whole arm is 9% and the front of the trunk 18%, giving 27% total body surface area. Superficial (redness only) areas would not be counted.
Answer
B · 27%
7.Clinical nursing
Answer: B · Raise the concern through the local safeguarding (adult protection) procedure
Why this is the answer
Financial abuse is a form of adult abuse. Nurses report concerns through safeguarding procedures, document facts accurately and involve the patient as appropriate.
Answer
B · Raise the concern through the local safeguarding (adult protection) procedure
8.Clinical nursing
Answer: D · They may have no fever and present with confusion, falls or reduced mobility
Why this is the answer
Older people may have a normal or low temperature and present with delirium, falls or general decline. Early warning scores and a high index of suspicion are important.
Answer
D · They may have no fever and present with confusion, falls or reduced mobility
9.Lab values & electrolytes
Answer: D · The result may be falsely high and should be repeated with better technique
Why this is the answer
Repeated fist clenching and a long tourniquet time release potassium from muscle and can cause hemolysis, both of which give a falsely high potassium. The patient is assessed and the test is repeated with correct technique; true hyperkalemia must not be missed.Checked against:Potassium Blood Test · MedlinePlus (NIH) (2024); Potassium test · MedlinePlus (NIH) (2025)
Answer
D · The result may be falsely high and should be repeated with better technique
10.Lab values & electrolytes
Answer: C · Heparin is adjusted using the aPTT or anti-Xa level, not the INR
Why this is the answer
Unfractionated heparin infusions are adjusted using the aPTT or anti-factor Xa level according to protocol. The INR monitors warfarin and is little affected by heparin at usual doses. Using the wrong test can cause under- or over-anticoagulation.Checked against:Partial Thromboplastin Time (PTT) Test · MedlinePlus (NIH) (2026); Prothrombin Time Test and INR (PT/INR) · MedlinePlus (NIH) (2024)
Answer
C · Heparin is adjusted using the aPTT or anti-Xa level, not the INR
11.Arterial blood gas interpretation
Answer: PaCO₂ = 35 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·18 + 8 = 35 mmHg
range: 33–37 mmHg
Answer
PaCO₂ = 35 mmHg
12.Arterial blood gas interpretation
Answer: added respiratory acidosis
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·12 + 8 = 26 → 24–28 mmHg
Compare
measured: 39 mmHg → added respiratory acidosis
Answer
added respiratory acidosis
13.ECG rhythm strip interpretation
Answer: QT = 0.44 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
11 small boxes from the start of the QRS to the end of the T wave
Convert
QT = 11 × 0.04 s = 0.44 s
Answer
QT = 0.44 s
A rough rule: at normal rates the QT should be less than half the R–R interval (here R–R = 1.12 s).
14.ECG rhythm strip interpretation
Answer: torsades de pointes
More ventricular rhythms: torsades de pointes is a polymorphic ventricular tachycardia, usually 150–250/min, in which the wide complexes change in height and twist around the baseline, pointing up for a few beats and then down. Textbooks link it to a prolonged QT interval, and magnesium sulfate is the drug resuscitation guidelines name for it. An idioventricular rhythm is a ventricular escape rhythm: regular, wide QRS (0.12 s or more), no P waves, at 20–40/min (an accelerated idioventricular rhythm runs at 40–100/min). Monomorphic VT has identical wide complexes at more than 100/min. VF is chaotic, without any repeating complex.
Five steps
1. Rate: very fast, the complexes are about 7 small boxes apart (about 214 per minute).
2. Rhythm: fast and roughly regular, but the height and direction of the complexes change in a repeating spindle pattern.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: wide and polymorphic; the complexes twist around the baseline, pointing up for a few beats and then down.
Interpretation
torsades de pointes
Answer
torsades de pointes
Torsades de pointes is a polymorphic VT linked to a prolonged QT interval. This is identification practice only.
15.Prioritization & delegation
Answer: B · Poor ventilation causing carbon dioxide to build up
Why this is the answer
A low pH with a high PaCO₂ and normal bicarbonate is respiratory acidosis. The patient is not breathing out enough carbon dioxide, so the priority is to support ventilation and escalate.
Answer
B · Poor ventilation causing carbon dioxide to build up
16.Prioritization & delegation
Answer: D · A patient with neutropenia after chemotherapy
Why this is the answer
When urgency is equal, the nurse cares for the most vulnerable patient first and patients with transmissible infections last. This lowers the risk of carrying organisms to an immunocompromised patient.