Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient is going home with a 24-hour Holter monitor. Which instruction is most important?
ARemove the monitor whenever symptoms occur and restart it
BStay in bed for the full 24 hours so the trace is clear
CKeep a diary of symptoms and activities with the times
DShower as normal with the monitor on
2.Med-surg: cardiovascular & respiratoryHard
A patient with rheumatoid arthritis is due to start an anti-TNF biologic drug. Which screening is essential beforehand?
AA peak flow diary for a month
BScreening for latent tuberculosis
CAn exercise ECG test on a treadmill
DA sweat chloride test
3.Med-surg: neuro, endocrine & renalMedium
Why do patients with CKD often take phosphate binders with meals?
AThey increase the absorption of phosphate from food in the gut
BThey replace the missing hormone erythropoietin
CThey lower blood potassium by binding it in the gut
DThey bind food phosphate that the kidneys cannot excrete
4.Med-surg: neuro, endocrine & renalHard
After a stroke, a patient suddenly cries or laughs at odd moments. They say they do not feel sad. Which response is most appropriate?
AAsk the doctor for a sedative to stop the outbursts
BIgnore it, because it shows that the patient is seeking attention from the staff
CTell the patient that crying will slow their recovery
DExplain that this is emotional lability after stroke and help the family understand
5.Med-surg: GI, perioperative & oncologyMedium
Why are urinary catheters removed as early as possible after surgery?
ABecause catheters always cause kidney stones
BTo reduce the risk of catheter-associated infection
CBecause the catheter stops the bowel working
DBecause patients cannot drink normally while a catheter is in place
6.Med-surg: GI, perioperative & oncologyHard
A patient who had a coronary stent placed two months ago, on aspirin and clopidogrel, presents with melaena and is now stable. What is the most appropriate approach to the antiplatelet drugs?
ADouble both doses, because bleeding means the stent is at greater risk of clotting
BReport the bleed; the team decides with cardiology input, balancing bleeding against stent thrombosis
CContinue both drugs unchanged and do not mention the bleeding to the team
DStop both drugs permanently, because any bleeding means they are no longer safe
7.Clinical nursingMedium
A patient has colicky abdominal pain, a swollen abdomen, vomiting and has not passed stool or wind for two days. What is the likely problem?
AIrritable bowel syndrome
BAppendicitis without complications
CBowel obstruction
DGastroenteritis
8.Clinical nursingHard
A nurse teaches a patient with heart failure about self-care. Which statement shows a need for further teaching?
A"I will report it if I need more pillows to sleep."
B"I only need to weigh myself once a month."
C"I will weigh myself each morning after passing urine."
D"I will take my water tablet in the morning."
9.Lab values & electrolytesMedium
A patient with HIV on antiretroviral therapy has an undetectable viral load. What does this mean?
AThe CD4 count must now be dangerously low too
BThe treatment can now be stopped without any risk
CThe treatment is suppressing the virus very well
DThe virus has been completely cured and removed
10.Lab values & electrolytesHard
A patient has a continuous heparin infusion for a pulmonary embolism. A new nurse plans to adjust the infusion using today's INR of 1.1. What should the experienced nurse explain?
AThe INR of 1.1 means the heparin rate must be doubled at once
BThe INR is the correct test, and 1.1 means heparin is therapeutic
CHeparin is adjusted using the aPTT or anti-Xa level, not the INR
DHeparin needs no laboratory monitoring once the infusion is started
11.Arterial blood gas interpretationMedium
Practice values: Na⁺ 138 mmol/L, glucose 7.2 mmol/L and urea 17.8 mmol/L. Calculate the serum osmolality Osm = 2·Na⁺ + glucose + urea to the nearest whole number.
Na⁺ 138 mmol/Lglucose 7.2 mmol/Lurea 17.8 mmol/L
Osm = mOsm/kg
12.Arterial blood gas interpretationHard
Practice values: Na⁺ 134, Cl⁻ 94 and HCO₃⁻ 14 mmol/L. Calculate the delta ratio (AG − 12)/(24 − HCO₃⁻), using AG = Na⁺ − (Cl⁻ + HCO₃⁻). Give two decimals.
Na⁺ 134 mmol/LCl⁻ 94 mmol/LHCO₃⁻ 14 mmol/L
delta ratio =
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1supraventricular tachycardia (SVT)
2sinus tachycardia
3atrial flutter, 2:1 conduction
4sinus bradycardia
14.ECG rhythm strip interpretationHard
Interpret this lead II strip with the five steps in order: rate, rhythm, P waves, PR interval, QRS duration. At which step do you find the first abnormal finding? Click it.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1rate
2rhythm
3P waves
4PR interval
5QRS duration
15.Prioritization & delegationMedium
A stable adult has abdominal pain and normal vital signs. They will need blood tests and a CT scan. Which ESI level fits?
ALevel 5
BLevel 4
CLevel 1
DLevel 3
16.Prioritization & delegationHard
A patient with a head injury has a pupil on one side that is now large and does not react to light. What should the nurse do?
ADim the room lights so the pupil can get smaller
BRecheck it at the next routine observation in four hours
CReport it at once, as it may mean the brain is being compressed
DDocument it, because pupils often differ slightly after a head injury
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · Keep a diary of symptoms and activities with the times
Why this is the answer
A Holter monitor records the ECG continuously during normal daily life. A diary of symptoms and activities lets the reviewer match symptoms such as palpitations or dizziness to the rhythm. The device is kept dry unless it is designed to be waterproof.
Answer
C · Keep a diary of symptoms and activities with the times
2.Med-surg: cardiovascular & respiratory
Answer: B · Screening for latent tuberculosis
Why this is the answer
TNF-alpha is essential for containing TB in granulomas. Anti-TNF drugs can reactivate latent TB, sometimes as severe disseminated disease. Patients are screened (history, chest X-ray, IGRA) and treated for latent TB before starting.
Answer
B · Screening for latent tuberculosis
3.Med-surg: neuro, endocrine & renal
Answer: D · They bind food phosphate that the kidneys cannot excrete
Why this is the answer
In CKD, phosphate retention leads to secondary hyperparathyroidism, renal bone disease and vascular calcification. Phosphate binders taken with meals bind dietary phosphate in the gut. Dietary phosphate is also limited.
Answer
D · They bind food phosphate that the kidneys cannot excrete
4.Med-surg: neuro, endocrine & renal
Answer: D · Explain that this is emotional lability after stroke and help the family understand
Why this is the answer
Emotional lability (pseudobulbar affect) is common after stroke: crying or laughter does not match the person's mood. Explaining it, staying calm and gently distracting the patient helps. True depression is also common and should be screened for separately.
Answer
D · Explain that this is emotional lability after stroke and help the family understand
5.Med-surg: GI, perioperative & oncology
Answer: B · To reduce the risk of catheter-associated infection
Why this is the answer
The risk of catheter-associated urinary tract infection increases with duration. Daily review of the need for a catheter, and early removal, reduce infection and help mobilisation.
Answer
B · To reduce the risk of catheter-associated infection
6.Med-surg: GI, perioperative & oncology
Answer: B · Report the bleed; the team decides with cardiology input, balancing bleeding against stent thrombosis
Why this is the answer
Early after coronary stenting, stopping dual antiplatelet therapy carries a high risk of stent thrombosis and MI, while continuing increases bleeding. Decisions are made by the medical team, ideally with cardiology and gastroenterology input; often aspirin is continued and the second agent paused briefly or continued depending on bleeding severity and endoscopic findings.
Answer
B · Report the bleed; the team decides with cardiology input, balancing bleeding against stent thrombosis
7.Clinical nursing
Answer: C · Bowel obstruction
Why this is the answer
Bowel obstruction causes distension, colicky pain, vomiting and absolute constipation. Patients are often kept nil by mouth with a nasogastric tube to decompress the stomach.
Answer
C · Bowel obstruction
8.Clinical nursing
Answer: B · "I only need to weigh myself once a month."
Why this is the answer
Daily weights at the same time with the same scales detect fluid retention early. A rapid gain, worsening breathlessness or needing more pillows should be reported.
Answer
B · "I only need to weigh myself once a month."
9.Lab values & electrolytes
Answer: C · The treatment is suppressing the virus very well
Why this is the answer
An undetectable viral load shows that antiretroviral therapy is suppressing viral replication. The virus remains in the body, so treatment must continue. People with a sustained undetectable viral load do not transmit HIV sexually.
Answer
C · The treatment is suppressing the virus very well
10.Lab values & electrolytes
Answer: C · Heparin is adjusted using the aPTT or anti-Xa level, not the INR
Why this is the answer
Unfractionated heparin infusions are adjusted using the aPTT or anti-factor Xa level according to protocol. The INR monitors warfarin and is little affected by heparin at usual doses. Using the wrong test can cause under- or over-anticoagulation.
Answer
C · Heparin is adjusted using the aPTT or anti-Xa level, not the INR
11.Arterial blood gas interpretation
Answer: Osm = 301 mOsm/kg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Calculated osmolality
Osm = 2·138 + 7.2 + 17.8 = 301 ≈ 301 mOsm/kg
Answer
Osm = 301 mOsm/kg
12.Arterial blood gas interpretation
Answer: delta ratio = 1.4
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 134 − (94 + 14) = 26
Delta ratio
(26 − 12)/(24 − 14) = 14/10 = 1.4
Answer
delta ratio = 1.4
Between 1 and 2: a pure high anion gap acidosis.
13.ECG rhythm strip interpretation
Answer: sinus tachycardia
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 13 small boxes, 1500 ÷ 13 ≈ 115 per minute.
2. Rhythm: regular, every R–R is 0.52 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.12 s, constant, within 0.12–0.20 s.
5. QRS: 0.10 s, narrow (below 0.12 s).
Interpretation
sinus tachycardia
Answer
sinus tachycardia
14.ECG rhythm strip interpretation
Answer: QRS duration
Five steps for every strip: 1. rate (300 or 1500 method, or the 6-second method if irregular); 2. rhythm: are the R–R intervals equal; 3. P waves: present, upright in lead II, one before every QRS and all alike; 4. PR interval: 0.12–0.20 s and constant; 5. QRS duration: below 0.12 s. Only after the five steps name the rhythm. Normal sinus rhythm passes all five: 60–100/min, regular, upright P before every QRS, PR 0.12–0.20 s, QRS below 0.12 s.
Five steps
1. Rate: R–R = 19 small boxes, 1500 ÷ 19 ≈ 79 per minute.
2. Rhythm: regular, every R–R is 0.76 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.18 s, constant, within 0.12–0.20 s.
5. QRS: 0.16 s, wide (0.12 s or more).
First abnormal step
QRS duration → sinus rhythm with wide QRS
Answer
QRS duration
15.Prioritization & delegation
Answer: D · Level 3
Why this is the answer
Blood tests (one resource) plus a CT scan (a second resource) make two resources, which is ESI level 3 when the vital signs are acceptable.
Answer
D · Level 3
16.Prioritization & delegation
Answer: C · Report it at once, as it may mean the brain is being compressed
Why this is the answer
A newly fixed, dilated pupil suggests pressure on the third cranial nerve from rising intracranial pressure or a bleed. It is a neurological emergency that needs immediate escalation.
Answer
C · Report it at once, as it may mean the brain is being compressed