Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient who has just started an antihypertensive feels dizzy when getting out of bed. What is the correct advice?
AStop taking the tablet without telling the doctor or nurse
BTake a double dose the next morning instead
CSit on the bed edge for a moment before standing
DStand up quickly so the blood keeps moving
2.Med-surg: cardiovascular & respiratoryHard
A day after a myocardial infarction, a patient has frequent ventricular ectopic beats on the monitor. Which blood results should be checked first?
AAmylase and lipase
BFerritin and vitamin B12
CAlbumin and bilirubin
DPotassium and magnesium
3.Med-surg: neuro, endocrine & renalMedium
A patient is starting nitrofurantoin for a UTI. Which teaching point is correct?
AIt must be taken only once a week
BIt should be taken on an empty stomach with milk
CIt turns the tears and sweat bright orange
DIt may turn the urine dark yellow or brown
4.Med-surg: neuro, endocrine & renalHard
A patient in a halo vest for a cervical spine fracture has a cardiac arrest. What must be immediately available?
AA pillow to raise the head and shoulders
BA hard board to slide under the vest
CThe tool to open the front of the vest for CPR
DScissors to cut through the skull pins
5.Med-surg: GI, perioperative & oncologyMedium
Which food advice reduces the risk of blockage with a new ileostomy?
ADrink very little fluid to keep the output thick
BSwallow food quickly without chewing much
CEat plenty of nuts and seeds from day one
DChew well, and bring in fibrous foods slowly
6.Med-surg: GI, perioperative & oncologyHard
Which group of signs suggests that a patient is entering the last days of life?
AReduced intake, mottled skin and changes in breathing
BClearer thinking and increased movement
CHigh blood pressure and very fast weight gain
DRising appetite, more energy and normal skin colour and warmth
7.Clinical nursingMedium
The WHO analgesic ladder recommends:
AGiving analgesia only when pain becomes severe
BStarting all patients on strong opioids
CUsing only non-drug methods for cancer pain
DMoving from non-opioids to weak and then strong opioids as pain increases
8.Clinical nursingHard
A nurse teaches a patient with heart failure about self-care. Which statement shows a need for further teaching?
A"I will weigh myself each morning after passing urine."
B"I will report it if I need more pillows to sleep."
C"I only need to weigh myself once a month."
D"I will take my water tablet in the morning."
9.Lab values & electrolytesMedium
A patient on warfarin for atrial fibrillation has a target INR of 2.0–3.0. How does the usual target for a patient with a mechanical mitral valve compare?
AMuch higher, about 5.0–6.0
BThe same, 2.0–3.0
CLower, about 1.0–1.5
DHigher, about 2.5–3.5
10.Lab values & electrolytesHard
A patient's total calcium is 7.6 mg/dL and the albumin is 2.0 g/dL. Using the common correction (add 0.8 mg/dL for each 1 g/dL that albumin is below 4.0), what is the corrected calcium?
A9.2 mg/dL, within the normal range
B7.6 mg/dL, below the normal range
C11.6 mg/dL, above the normal range
D6.0 mg/dL, well below the normal range
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 75 mmHg (10.0 kPa). Use the rule that in chronic respiratory acidosis HCO₃⁻ rises by 3.5 mmol/L for every 10 mmHg that PaCO₂ is above 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
At sea level, a practice gas taken on 28% oxygen shows PaO₂ 65 mmHg (8.7 kPa) and PaCO₂ 42 mmHg (5.6 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1first-degree AV block
2sinus bradycardia
3junctional rhythm
4normal sinus rhythm
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1supraventricular tachycardia (SVT)
2sinus tachycardia
3ventricular tachycardia
4atrial flutter, 2:1 conduction
15.Prioritization & delegationMedium
On the first day after abdominal surgery, a patient has a temperature of 37.9 °C and reduced breath sounds at the lung bases. Which nursing action is most helpful?
ARestrict oral fluids so that the lungs do not fill up with extra fluid
BGive a cough suppressant so that the incision is not strained
CEncourage deep breathing, coughing and use of the incentive spirometer
DKeep the patient lying flat in bed to rest the incision fully
16.Prioritization & delegationHard
A patient with diabetic ketoacidosis is about to start an IV insulin infusion. The serum potassium is 3.0 mEq/L. What should the nurse do?
AIgnore the result, since potassium is always high in this condition and will correct itself
BReport the result before starting, because insulin will push potassium even lower
CGive the insulin as a fast bolus to bring the potassium up
DStart the insulin at once, because the glucose is the bigger problem
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · Sit on the bed edge for a moment before standing
Why this is the answer
Postural (orthostatic) hypotension is common when starting antihypertensives. Changing position slowly reduces the risk of falls. Persistent symptoms should be reported so lying and standing blood pressures can be checked and the dose reviewed.
Answer
C · Sit on the bed edge for a moment before standing
2.Med-surg: cardiovascular & respiratory
Answer: D · Potassium and magnesium
Why this is the answer
Low potassium and low magnesium both increase ventricular irritability and the risk of VT and VF after an MI. They are checked and corrected, usually keeping potassium in the upper part of the normal range. The patient is also assessed for ischaemia and haemodynamic change.
Answer
D · Potassium and magnesium
3.Med-surg: neuro, endocrine & renal
Answer: D · It may turn the urine dark yellow or brown
Why this is the answer
Nitrofurantoin can make urine dark yellow or brown, which is harmless. Taking it with food reduces nausea. Patients should report breathlessness, cough or tingling, which are rare but serious effects.
Answer
D · It may turn the urine dark yellow or brown
4.Med-surg: neuro, endocrine & renal
Answer: C · The tool to open the front of the vest for CPR
Why this is the answer
The tool to release the anterior vest is kept attached to the vest so it can be opened quickly for CPR or airway management. Pin sites need regular care to prevent infection, and the patient needs teaching about skin care under the vest.
Answer
C · The tool to open the front of the vest for CPR
5.Med-surg: GI, perioperative & oncology
Answer: D · Chew well, and bring in fibrous foods slowly
Why this is the answer
Fibrous foods such as nuts, sweetcorn, dried fruit and fruit skins can form a bolus that blocks the narrow stoma. Chewing thoroughly, introducing these foods slowly and drinking enough fluid reduce the risk. Symptoms of blockage include cramping, a swollen stoma and no output.
Answer
D · Chew well, and bring in fibrous foods slowly
6.Med-surg: GI, perioperative & oncology
Answer: A · Reduced intake, mottled skin and changes in breathing
Why this is the answer
Signs include increasing drowsiness, reduced intake, mottled cool peripheries, changes in breathing such as pauses, and noisy secretions. Recognising them allows care to focus on comfort and family support.
Answer
A · Reduced intake, mottled skin and changes in breathing
7.Clinical nursing
Answer: D · Moving from non-opioids to weak and then strong opioids as pain increases
Why this is the answer
The ladder moves from non-opioids (such as paracetamol) to weak opioids and then strong opioids, with adjuvants at any step. Regular dosing is preferred for persistent pain.
Answer
D · Moving from non-opioids to weak and then strong opioids as pain increases
8.Clinical nursing
Answer: C · "I only need to weigh myself once a month."
Why this is the answer
Daily weights at the same time with the same scales detect fluid retention early. A rapid gain, worsening breathlessness or needing more pillows should be reported.
Answer
C · "I only need to weigh myself once a month."
9.Lab values & electrolytes
Answer: D · Higher, about 2.5–3.5
Why this is the answer
Mechanical heart valves, especially in the mitral position, have a high risk of thrombosis, so the INR target is usually higher, about 2.5–3.5. An INR of 5 or more carries a high bleeding risk.Checked against:Label: WARFARIN SODIUM tablet · DailyMed (NLM/FDA) (2012)
Answer
D · Higher, about 2.5–3.5
10.Lab values & electrolytes
Answer: A · 9.2 mg/dL, within the normal range
Why this is the answer
Corrected calcium = 7.6 + 0.8 × (4.0 − 2.0) = 9.2 mg/dL, which is normal. Low albumin lowers the bound fraction of calcium; the correction is only an estimate, and an ionized calcium is more accurate when it matters.Checked against:Calcium blood test · MedlinePlus (NIH) (2025)
Answer
A · 9.2 mg/dL, within the normal range
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 36.25 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|75 − 40| = 35 mmHg → 3.5 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 + 3.5·3.5 = 36.25 mmol/L
Answer
HCO₃⁻ = 36.25 mmol/L
12.Arterial blood gas interpretation
Answer: A–a gradient = 82.14 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 30 small boxes, 1500 ÷ 30 ≈ 50 per minute.
2. Rhythm: regular, every R–R is 1.20 s.
3. P waves: inverted, just after each QRS.
4. PR interval: not measurable.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
junctional rhythm
Answer
junctional rhythm
14.ECG rhythm strip interpretation
Answer: ventricular tachycardia
Ventricular rhythms: ventricular tachycardia is a run of three or more wide (0.12 s or more) complexes in a row at more than 100/min, usually 150–250/min, regular, without related P waves. Ventricular fibrillation is a chaotic, irregular waveform with no identifiable P waves, QRS complexes or T waves and no countable rate. Asystole is an almost flat line with no ventricular activity; a flat line is always confirmed by checking the patient, the leads and the gain and a second lead. In resuscitation guidelines VF and pulseless VT are the shockable rhythms and asystole is not.
Five steps
1. Rate: R–R = 10 small boxes, 1500 ÷ 10 ≈ 150 per minute.
2. Rhythm: regular, every R–R is 0.40 s.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: 0.14 s, wide (0.12 s or more).
Interpretation
ventricular tachycardia
Answer
ventricular tachycardia
In resuscitation guidelines VF and pulseless VT are the shockable rhythms. This is identification practice only.
15.Prioritization & delegation
Answer: C · Encourage deep breathing, coughing and use of the incentive spirometer
Why this is the answer
Reduced basal breath sounds and a mild temperature early after surgery often mean atelectasis. Deep breathing, coughing, incentive spirometry and early mobilization help re-expand the lungs.
Answer
C · Encourage deep breathing, coughing and use of the incentive spirometer
16.Prioritization & delegation
Answer: B · Report the result before starting, because insulin will push potassium even lower
Why this is the answer
Insulin drives potassium into cells and can cause dangerous hypokalemia, so a low starting potassium must be reported. US (ADA) guidance delays insulin until potassium is at least 3.3 mEq/L; UK (JBDS) guidance asks for urgent senior review and potassium replacement. Either way, the prescriber decides.
Answer
B · Report the result before starting, because insulin will push potassium even lower