Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Which advice is most helpful for a patient with Raynaud's phenomenon?
AKeep the whole body warm, wear gloves and stop smoking
BRub the fingers hard with snow during an attack
CSoak the hands in cold water to toughen the vessels
DTake a decongestant tablet before going outdoors
2.Med-surg: cardiovascular & respiratoryHard
Four hours after PCI via the femoral artery, the groin dressing is soaked with blood and a firm swelling is growing. What is the immediate action?
ARemove the dressing and leave the site open to the air
BHelp the patient sit up and walk to the toilet to void
CIncrease the heparin infusion rate so that no clot forms at the site
DApply firm pressure just above the puncture site and call for help
3.Med-surg: neuro, endocrine & renalMedium
A patient with SIADH has a sodium of 126 mmol/L and mild symptoms. Which treatment is usually first-line?
AFluid restriction
BIV 5% glucose infusion
CDesmopressin
DExtra oral water
4.Med-surg: neuro, endocrine & renalHard
A patient in thyroid storm has a temperature of 40 °C (104 °F). Which measure for the fever is usually avoided?
ACooling blankets
BParacetamol (acetaminophen)
CFanning with cool air
DAspirin
5.Med-surg: GI, perioperative & oncologyMedium
Why might a patient's platelet count be monitored while they receive heparin?
ATo see whether the patient has an infection
BTo detect heparin-induced thrombocytopenia
CTo check whether the heparin is causing anaemia
DTo measure the heparin dose in the blood exactly
6.Med-surg: GI, perioperative & oncologyHard
A patient admitted for an elective general anaesthetic mentions that they ate a slice of toast 3 hours ago. What should the nurse do?
ASay nothing, since toast is a light food
BAsk the patient to try to vomit to empty the stomach
CGive a large drink to wash the food through
DInform the anaesthetist, as surgery may be delayed
7.Clinical nursingMedium
Which blood results are typical of Addison's disease (primary adrenal insufficiency)?
AHigh glucose and high calcium
BLow haemoglobin and high platelets
CHigh sodium and low potassium
DLow sodium and high potassium
8.Clinical nursingHard
A hypotensive postoperative patient is given a fluid bolus. Which findings suggest a good response?
AThe heart rate falls, blood pressure rises and urine output improves
BThe respiratory rate rises and new lung crackles appear
CThe heart rate rises further and the patient becomes more confused
DThe capillary refill time becomes longer
9.Lab values & electrolytesMedium
A patient with sickle cell disease takes hydroxyurea. Which laboratory test is monitored regularly for an adverse effect?
ASerum amylase level
BComplete blood count
CUrine ketone level
DSerum lithium level
10.Lab values & electrolytesHard
A patient on clozapine for 2 years has been stable. Which statement shows a need for further teaching?
A"I can stop my blood tests since I feel well"
B"I'll report a sore throat or fever at once"
C"I'll keep all my scheduled blood test visits"
D"I'll tell other doctors that I take clozapine"
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 18 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 18 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic alkalosis with HCO₃⁻ 45 mmol/L. Use expected PaCO₂ = 0.7·HCO₃⁻ + 21 to find the expected PaCO₂.
HCO₃⁻ 45 mmol/L
PaCO₂ = mmHg
13.ECG rhythm strip interpretationMedium
This lead II strip shows atrial flutter. Measure the flutter-wave interval and find the atrial rate in beats per minute.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
atrial rate = bpm
14.ECG rhythm strip interpretationHard
A monitored patient is found unresponsive and not breathing normally, and no carotid pulse can be felt. The monitor shows this organised rhythm. What is this situation called? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1pulseless electrical activity (PEA)
2asystole
3junctional rhythm
4ventricular fibrillation
15.Prioritization & delegationMedium
When making patient assignments, what should the charge nurse consider first?
AMatching each patient’s needs to staff competence
BLetting staff choose the patients they prefer
CGiving the newest staff the most complex patients
DGiving each nurse patients in rooms next to each other
16.Prioritization & delegationHard
A severely malnourished patient started nutrition two days ago and now has weakness and confusion. Which laboratory result should the nurse check first?
ASerum amylase
BSerum phosphate
CSerum cholesterol
DThyroid hormone
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · Keep the whole body warm, wear gloves and stop smoking
Why this is the answer
Keeping the core and hands warm, wearing gloves and stopping smoking reduce attacks. Vasoconstrictors such as decongestants and nicotine make it worse. During an attack, gentle warming of the hands is advised.
Answer
A · Keep the whole body warm, wear gloves and stop smoking
2.Med-surg: cardiovascular & respiratory
Answer: D · Apply firm pressure just above the puncture site and call for help
Why this is the answer
Bleeding or haematoma at the arterial access site is a common complication, made worse by antiplatelet and anticoagulant drugs. Firm manual pressure just above the skin puncture (over the arterial puncture), with the patient lying flat, is the first action, together with vital signs, distal pulses and escalation. Retroperitoneal bleeding can be hidden, so watch for back pain and hypotension.
Answer
D · Apply firm pressure just above the puncture site and call for help
3.Med-surg: neuro, endocrine & renal
Answer: A · Fluid restriction
Why this is the answer
In SIADH the body retains water. Fluid restriction is the first-line treatment for mild to moderate cases, along with treating the cause. Hypotonic fluids and desmopressin would lower sodium further. Severe symptoms (seizures, reduced consciousness) need hypertonic saline in a monitored setting.
Answer
A · Fluid restriction
4.Med-surg: neuro, endocrine & renal
Answer: D · Aspirin
Why this is the answer
Aspirin (salicylates) displaces thyroid hormone from binding proteins, raising free hormone levels. Paracetamol (acetaminophen) and external cooling are used instead, together with treatment for the storm itself.
Answer
D · Aspirin
5.Med-surg: GI, perioperative & oncology
Answer: B · To detect heparin-induced thrombocytopenia
Why this is the answer
Heparin-induced thrombocytopenia is an immune reaction, usually 5–10 days after starting heparin, that lowers platelets and paradoxically causes thrombosis. Monitoring depends on risk and local policy.
Answer
B · To detect heparin-induced thrombocytopenia
6.Med-surg: GI, perioperative & oncology
Answer: D · Inform the anaesthetist, as surgery may be delayed
Why this is the answer
Solid food is usually stopped 6 hours before anaesthesia because of aspiration risk. The anaesthetist decides whether to delay or change the plan; the nurse reports accurately and does not hide the information.
Answer
D · Inform the anaesthetist, as surgery may be delayed
7.Clinical nursing
Answer: D · Low sodium and high potassium
Why this is the answer
Without aldosterone, the kidneys lose sodium and retain potassium. Patients may also have low blood pressure, low glucose and increased skin pigmentation.
Answer
D · Low sodium and high potassium
8.Clinical nursing
Answer: A · The heart rate falls, blood pressure rises and urine output improves
Why this is the answer
After a fluid challenge, a falling heart rate, rising blood pressure, better capillary refill, improving consciousness and urine output suggest fluid responsiveness. New crackles or breathlessness suggest fluid overload.
Answer
A · The heart rate falls, blood pressure rises and urine output improves
9.Lab values & electrolytes
Answer: B · Complete blood count
Why this is the answer
Hydroxyurea increases fetal hemoglobin and reduces sickling crises, but it can suppress the bone marrow. The CBC, including neutrophils and platelets, is monitored regularly, and doses are adjusted if counts fall.Checked against:Sickle cell disease · MedlinePlus (NIH) (2026)
Answer
B · Complete blood count
10.Lab values & electrolytes
Answer: A · "I can stop my blood tests since I feel well"
Why this is the answer
Clozapine requires ongoing ANC monitoring according to the schedule, because severe neutropenia can occur without warning. The patient must keep blood test appointments and report signs of infection at once.
Answer
A · "I can stop my blood tests since I feel well"
11.Arterial blood gas interpretation
Answer: PaCO₂ = 35 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·18 + 8 = 35 mmHg
range: 33–37 mmHg
Answer
PaCO₂ = 35 mmHg
12.Arterial blood gas interpretation
Answer: PaCO₂ = 52.5 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
0.7·45 + 21 = 52.5 mmHg
Answer
PaCO₂ = 52.5 mmHg
The rise has a limit: PaCO₂ rarely goes above about 55 mmHg from compensation alone.
13.ECG rhythm strip interpretation
Answer: atrial rate = 300 bpm
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Flutter waves
F–F = 5 small boxes = 0.20 s → 1500 ÷ 5 = 300 per minute
QRS complexes
R–R = 20 small boxes = 0.80 s → 1500 ÷ 20 = 75 per minute
conduction ratio = 300 ÷ 75 = 4:1
Answer
atrial rate = 300 bpm
14.ECG rhythm strip interpretation
Answer: pulseless electrical activity (PEA)
Pulseless electrical activity (PEA): PEA cannot be seen on a strip. The monitor shows organised electrical activity (a rhythm other than VF, VT or asystole) but the patient has no palpable pulse, so it is recognised by checking the patient. In adult resuscitation guidelines PEA and asystole are the non-shockable cardiac arrest rhythms: high-quality CPR, epinephrine as soon as possible and a search for reversible causes (the Hs and Ts, such as hypovolaemia, hypoxia, tension pneumothorax and cardiac tamponade). VF and pulseless VT are the shockable rhythms.
What the strip shows
1. Rate: R–R = 35 small boxes, 1500 ÷ 35 ≈ 43 per minute.
2. Rhythm: regular, every R–R is 1.40 s.
3. P waves: inverted, just after each QRS.
4. PR interval: not measurable.
5. QRS: 0.06 s, narrow (below 0.12 s).
junctional rhythm
What the patient shows
no pulse despite organised electrical activity: pulseless electrical activity (PEA), a non-shockable cardiac arrest rhythm
Answer
pulseless electrical activity (PEA)
Answer
pulseless electrical activity (PEA)
PEA is recognised at the bedside, never from the strip alone. This is exam practice, not clinical guidance.
15.Prioritization & delegation
Answer: A · Matching each patient’s needs to staff competence
Why this is the answer
Assignments are based mainly on patient acuity and needs and on each staff member’s skills and scope. Geography and continuity of care help, but they come after safety.
Answer
A · Matching each patient’s needs to staff competence
16.Prioritization & delegation
Answer: B · Serum phosphate
Why this is the answer
In refeeding syndrome, a sudden change to carbohydrate metabolism moves phosphate, potassium and magnesium into cells. Low phosphate can cause weakness, confusion, heart failure and breathing problems.