Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
How can a patient reduce wound pain when coughing after abdominal surgery?
ALie flat on the back with the legs straight
BHold the breath for as long as possible
CAvoid coughing completely until all the stitches are removed
DHold a pillow firmly against the wound while coughing
2.Med-surg: cardiovascular & respiratoryHard
A nurse is planning care for four patients. Which patient should be assessed first?
AA patient with a venous ulcer due for a dressing change
BA patient with COPD whose SpO₂ fell from 90% to 83% with new drowsiness
CA patient with stable heart failure waiting for the daily weight
DA patient with controlled hypertension asking about salt
3.Med-surg: neuro, endocrine & renalMedium
Why should long-term steroid treatment not be stopped suddenly?
AThe steroids build up and become toxic after they are stopped
BStopping suddenly makes the bones grow too quickly and then fracture
CStopping causes the blood glucose to fall sharply
DThe suppressed adrenal glands cannot make enough cortisol at once
4.Med-surg: neuro, endocrine & renalHard
During a water deprivation test for suspected diabetes insipidus, the patient loses more than 3% of body weight and becomes hypotensive. What should the nurse do?
AStop the test and inform the doctor
BGive the patient a large drink and then restart the test
CContinue the test, because this result is expected
DGive desmopressin without a prescription
5.Med-surg: GI, perioperative & oncologyMedium
What is TENS?
AA device that sends mild electrical pulses through skin pads
BA type of epidural catheter inserted in theatre
CA pain score used for babies
DA strong opioid given through the skin as a weekly adhesive patch
6.Med-surg: GI, perioperative & oncologyHard
During general anaesthesia, a patient develops jaw rigidity, rising end-tidal CO₂ and tachycardia, then a rapidly rising temperature. Which drug is the specific treatment?
AParacetamol
BDantrolene
CNaloxone
DSuxamethonium
7.Clinical nursingMedium
A patient's low potassium does not improve despite potassium replacement. Which other electrolyte should be checked?
AChloride
BSodium
CMagnesium
DPhosphate
8.Clinical nursingHard
In a patient with a head injury, which is usually the earliest sign of rising intracranial pressure?
AA change in level of consciousness
BA slow pulse with high blood pressure
CIrregular breathing pauses
DA fixed, dilated pupil on both sides
9.Lab values & electrolytesMedium
A stool test for Clostridioides difficile is ordered. Which sample is appropriate?
AAn unformed (liquid or soft) stool
BAny stool after a laxative dose
CA rectal swab from a patient with constipation
DA formed, hard stool sample
10.Lab values & electrolytesHard
A patient's total calcium is 7.6 mg/dL and the albumin is 2.0 g/dL. Using the common correction (add 0.8 mg/dL for each 1 g/dL that albumin is below 4.0), what is the corrected calcium?
A6.0 mg/dL, well below the normal range
B9.2 mg/dL, within the normal range
C11.6 mg/dL, above the normal range
D7.6 mg/dL, below the normal range
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.13, PaCO₂ 74 mmHg (9.9 kPa) and HCO₃⁻ 24 mmol/L. The primary disorder is respiratory acidosis. How far is it compensated? Click your answer.
pH 7.13PaCO₂ 74 mmHg (9.9 kPa)HCO₃⁻ 24 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
Practice values: Na⁺ 144, Cl⁻ 109, HCO₃⁻ 18 mmol/L and albumin 36 g/L. Find the albumin-corrected anion gap AGc = AG + 0.25·(40 − albumin).
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1normal sinus rhythm
2first-degree AV block
3atrial fibrillation
4sinus rhythm with PVCs
14.ECG rhythm strip interpretationHard
This lead II strip shows second-degree AV block type I (Wenckebach). Measure the PR interval of the last conducted beat before a non-conducted P wave (the longest PR), in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
longest PR = s
15.Prioritization & delegationMedium
A conscious patient with hypoglycemia drank juice 15 minutes ago. The glucose is now 62 mg/dL (3.4 mmol/L). What should the nurse do next?
AWait another hour, because juice can take a long time to work
BRecord the result and recheck the glucose at the usual time before the evening meal
CGive another serving of fast-acting carbohydrate and recheck in 15 minutes
DGive the next scheduled dose of rapid-acting insulin with the meal
16.Prioritization & delegationHard
Which nursing approach may raise intracranial pressure in a patient with a head injury?
ASpacing out care with rest periods in between activities
BKeeping the head in line with the body
CKeeping the room calm and quiet
DDoing suctioning, turning and bathing all at the same time
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · Hold a pillow firmly against the wound while coughing
Why this is the answer
Splinting the incision with a pillow or folded towel supports the wound, reduces pain and makes effective coughing easier. Combined with good analgesia and deep breathing, this helps clear secretions and prevents atelectasis and pneumonia.
Answer
D · Hold a pillow firmly against the wound while coughing
2.Med-surg: cardiovascular & respiratory
Answer: B · A patient with COPD whose SpO₂ fell from 90% to 83% with new drowsiness
Why this is the answer
A falling saturation with new drowsiness suggests acute respiratory failure, possibly with hypercapnia, and needs immediate assessment. The other patients are stable and their needs can wait briefly.
Answer
B · A patient with COPD whose SpO₂ fell from 90% to 83% with new drowsiness
3.Med-surg: neuro, endocrine & renal
Answer: D · The suppressed adrenal glands cannot make enough cortisol at once
Why this is the answer
Long-term glucocorticoids suppress ACTH, and the adrenal glands shrink. Stopping abruptly can cause adrenal insufficiency or crisis. Doses are reduced gradually so the glands can recover.
Answer
D · The suppressed adrenal glands cannot make enough cortisol at once
4.Med-surg: neuro, endocrine & renal
Answer: A · Stop the test and inform the doctor
Why this is the answer
In DI, the patient keeps passing dilute urine despite fluid restriction and can become dangerously dehydrated. Significant weight loss, hypotension or a high sodium are reasons to stop the test and get medical review.
Answer
A · Stop the test and inform the doctor
5.Med-surg: GI, perioperative & oncology
Answer: A · A device that sends mild electrical pulses through skin pads
Why this is the answer
TENS is thought to reduce pain partly through the gate-control mechanism. It is non-invasive and patient-controlled, but is avoided over certain areas and with some implanted devices.
Answer
A · A device that sends mild electrical pulses through skin pads
6.Med-surg: GI, perioperative & oncology
Answer: B · Dantrolene
Why this is the answer
Malignant hyperthermia is treated by stopping triggering agents, hyperventilating with 100% oxygen, giving IV dantrolene (which reduces calcium release from the sarcoplasmic reticulum), active cooling and treating hyperkalaemia and arrhythmias. Suxamethonium is a trigger.
Answer
B · Dantrolene
7.Clinical nursing
Answer: C · Magnesium
Why this is the answer
Hypomagnesaemia increases renal potassium loss and makes hypokalaemia hard to correct. Magnesium must be replaced as well.
Answer
C · Magnesium
8.Clinical nursing
Answer: A · A change in level of consciousness
Why this is the answer
Subtle changes in consciousness, such as restlessness, confusion or a falling GCS, are often the first signs. Pupil changes and Cushing's triad (hypertension, bradycardia, irregular breathing) are late signs.
Answer
A · A change in level of consciousness
9.Lab values & electrolytes
Answer: A · An unformed (liquid or soft) stool
Why this is the answer
C. difficile testing is done on unformed stool from patients with diarrhea, because many people carry the organism without disease. Testing formed stool, or stool after laxatives, can lead to misdiagnosis.Checked against:C. diff Testing · MedlinePlus (NIH) (2026)
Answer
A · An unformed (liquid or soft) stool
10.Lab values & electrolytes
Answer: B · 9.2 mg/dL, within the normal range
Why this is the answer
Corrected calcium = 7.6 + 0.8 × (4.0 − 2.0) = 9.2 mg/dL, which is normal. Low albumin lowers the bound fraction of calcium; the correction is only an estimate, and an ionized calcium is more accurate when it matters.Checked against:Calcium blood test · MedlinePlus (NIH) (2025)
Answer
B · 9.2 mg/dL, within the normal range
11.Arterial blood gas interpretation
Answer: uncompensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.13: acidaemia (below 7.35)
PaCO₂ 74 mmHg: high (35–45)
HCO₃⁻ 24 mmol/L: normal (22–26)
Compensation
uncompensated
Answer
uncompensated
12.Arterial blood gas interpretation
Answer: AGc = 18 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 144 − (109 + 18) = 17
Correction for albumin
17 + 0.25·(40 − 36) = 18 mmol/L
Answer
AGc = 18 mmol/L
Above about 12 after correction: a high anion gap.
13.ECG rhythm strip interpretation
Answer: sinus rhythm with PVCs
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: 8 QRS complexes in 6 s, × 10 = 80 per minute.
2. Rhythm: regular (0.80 s) except for the early beats and the pause after each of them.
3. P waves: upright before every narrow QRS; none before the early wide beats.
4. PR interval: 0.16 s, constant, within 0.12–0.20 s.
5. QRS: 0.08 s in the sinus beats; the early beats are wide (0.16 s) and bizarre, with the T wave pointing the other way.
Interpretation
sinus rhythm with PVCs
Answer
sinus rhythm with PVCs
14.ECG rhythm strip interpretation
Answer:longest PR = 0.36 s
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
March out the P waves
P–P = 0.88 s, regular; one P wave in every 4 is not conducted
PR in each group
PR₁ = 0.18 s, PR₂ = 0.30 s, PR₃ = 0.36 s
Answer
longest PR = 0.36 s
The biggest step in PR comes between the first and second beats of a group; later steps are smaller, which is why the R–R intervals shorten before the pause.
15.Prioritization & delegation
Answer: C · Give another serving of fast-acting carbohydrate and recheck in 15 minutes
Why this is the answer
If the glucose is still below the hypoglycemia threshold after treatment (70 mg/dL in US guidance, 4.0 mmol/L in UK guidance), the fast-acting carbohydrate is repeated and the glucose rechecked. Once it is normal, a snack or meal helps keep it stable.
Answer
C · Give another serving of fast-acting carbohydrate and recheck in 15 minutes
16.Prioritization & delegation
Answer: D · Doing suctioning, turning and bathing all at the same time
Why this is the answer
Clustering several stimulating activities can cause a sustained rise in intracranial pressure. Spacing care, keeping the neck straight and a calm environment help keep it down.
Answer
D · Doing suctioning, turning and bathing all at the same time