Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient with a long QT interval develops a polymorphic ventricular tachycardia that twists around the baseline but still has a pulse. Which drug is used first?
AOral digoxin
BIntravenous adenosine
CIntravenous magnesium sulfate
DIntravenous potassium chloride as a bolus
2.Med-surg: cardiovascular & respiratoryHard
During a thrombolytic infusion for an MI, the patient develops a sudden severe headache, vomiting and new confusion. What should the nurse do first?
AContinue the infusion, as headache is a common side effect
BStop the infusion and call for urgent medical help
CSlow the infusion and give an antiemetic
DGive a second dose to finish the treatment
3.Med-surg: neuro, endocrine & renalMedium
A man starts tamsulosin for BPH. Which teaching point is most important?
AExpect the drug to shrink the prostate within a day
BTake it with grapefruit juice to make it work better
CStop it if the urine stream improves
DStand up slowly, because it can make you dizzy
4.Med-surg: neuro, endocrine & renalHard
A prescription reads "Insulin 10U". Why is this a safety problem?
AThere is no problem as long as the nurse can read it
B"U" means the insulin must be given intravenously
CInsulin doses must always be written in millilitres
D"U" can be misread as a zero, giving a tenfold dose
5.Med-surg: GI, perioperative & oncologyMedium
Why is regular (scheduled) analgesia often preferred to "as required" doses in the first days after major surgery?
AIt allows doses higher than the maximum daily limit to be given
BIt completely prevents all opioid side effects
CIt removes the need to assess the patient's pain during the day
DIt keeps drug levels steady and prevents severe peaks of pain
6.Med-surg: GI, perioperative & oncologyHard
A patient with advanced cancer who has capacity decides to stop chemotherapy. The family insists that treatment must continue. What should the nurse do?
AAsk the family to sign a new consent form
BTell the patient that stopping is not allowed
CSupport the patient's decision and help the team talk with the family
DContinue treatment because the family has asked for it
7.Clinical nursingMedium
Why are patients advised to rinse their mouth after using an inhaled corticosteroid?
ATo make the drug work faster
BTo stop the drug from being absorbed in the lungs
CTo prevent tooth decay from the sugar in it
DTo reduce the risk of oral thrush
8.Clinical nursingHard
A nurse is unsure whether a prescribed dose of a high-risk drug is correct. What is the safest action?
AAsk the patient whether the dose looks the same as usual and give it
BGive half the dose as a compromise until the doctor is available
CWithhold it and check with the prescriber or pharmacist first
DGive the dose because the doctor has signed the prescription
9.Lab values & electrolytesMedium
On the first day after major surgery, a patient's white cell count is 12.5 × 10³/µL, with no fever or wound signs. What is the best interpretation?
ADefinite wound infection that needs antibiotics now
BA laboratory error, since surgery lowers white cells
CA common stress response to surgery that is monitored
DA sign of leukemia that needs bone marrow testing
10.Lab values & electrolytesHard
A patient with a large, fast-growing lymphoma will start chemotherapy tomorrow. Which plan best prevents tumor lysis syndrome?
ANo special measures, because the risk starts only after a week
BCalcium supplements and a high-phosphate diet during treatment
CIV hydration, a uric acid-lowering drug and frequent electrolytes
DFluid restriction and a high-potassium diet before the treatment
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 10 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 10 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.17, PaCO₂ 43 mmHg (5.7 kPa), HCO₃⁻ 15 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.17PaCO₂ 43 mmHg (5.7 kPa)HCO₃⁻ 15 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial flutter, 2:1 conduction
2accelerated junctional rhythm
3sinus tachycardia
4supraventricular tachycardia (SVT)
14.ECG rhythm strip interpretationHard
Interpret this lead II strip. Which interpretation can you defend from this single strip? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
12:1 AV block (type undetermined)
2second-degree AV block type II
3first-degree AV block
4third-degree (complete) AV block
15.Prioritization & delegationMedium
A nurse teaches a patient about storing insulin at home. Which statement shows a need for further teaching?
A“I will keep my spare insulin in the freezer so it lasts longer.”
B“I will check the expiry date on the label before I use the vial.”
C“I will keep unopened insulin in the fridge.”
D“I will not leave my insulin in a hot car.”
16.Prioritization & delegationHard
A chemical cleaning fluid splashes into a patient’s eye. What should the nurse do first?
AGive antibiotic eye drops first
BFlush the eye with plenty of water or saline straight away
CCover the eye with a dry patch and wait for the provider
DRub the eye gently with a clean tissue to remove the chemical
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · Intravenous magnesium sulfate
Why this is the answer
Torsades de pointes is treated with IV magnesium, plus correction of low potassium and stopping drugs that prolong the QT interval. If the patient loses their pulse, defibrillation is needed. Potassium must never be given as an IV bolus.
Answer
C · Intravenous magnesium sulfate
2.Med-surg: cardiovascular & respiratory
Answer: B · Stop the infusion and call for urgent medical help
Why this is the answer
Sudden neurological change during or after thrombolysis suggests intracranial haemorrhage. The infusion is stopped immediately, help is called, and urgent CT and reversal are considered. Neurological observations continue.
Answer
B · Stop the infusion and call for urgent medical help
3.Med-surg: neuro, endocrine & renal
Answer: D · Stand up slowly, because it can make you dizzy
Why this is the answer
Tamsulosin relaxes smooth muscle in the prostate and bladder neck, improving urine flow within days. It can cause postural hypotension and dizziness, especially after the first dose, so patients rise slowly.
Answer
D · Stand up slowly, because it can make you dizzy
4.Med-surg: neuro, endocrine & renal
Answer: D · "U" can be misread as a zero, giving a tenfold dose
Why this is the answer
A handwritten "U" can look like a 0, turning 10 units into 100. The word "units" must be written in full. Insulin errors are a well-known cause of serious harm.
Answer
D · "U" can be misread as a zero, giving a tenfold dose
5.Med-surg: GI, perioperative & oncology
Answer: D · It keeps drug levels steady and prevents severe peaks of pain
Why this is the answer
Predictable, continuous postoperative pain is best managed with regular multimodal analgesia (for example paracetamol and, where safe, an NSAID), with as-needed doses for breakthrough pain. Pain and side effects are still assessed regularly.
Answer
D · It keeps drug levels steady and prevents severe peaks of pain
6.Med-surg: GI, perioperative & oncology
Answer: C · Support the patient's decision and help the team talk with the family
Why this is the answer
A competent adult can refuse treatment. The nurse advocates for the patient, supports communication with the family and team, and helps plan symptom control and palliative care.
Answer
C · Support the patient's decision and help the team talk with the family
7.Clinical nursing
Answer: D · To reduce the risk of oral thrush
Why this is the answer
Inhaled steroid deposited in the mouth and throat can cause oral candidiasis and a hoarse voice. Rinsing and using a spacer reduce this.
Answer
D · To reduce the risk of oral thrush
8.Clinical nursing
Answer: C · Withhold it and check with the prescriber or pharmacist first
Why this is the answer
Nurses must understand any drug they administer. If a dose seems wrong, they should check with the prescriber or pharmacist and document the action.
Answer
C · Withhold it and check with the prescriber or pharmacist first
9.Lab values & electrolytes
Answer: C · A common stress response to surgery that is monitored
Why this is the answer
A mild leukocytosis is common after surgery because of tissue injury and the stress response. It is monitored along with temperature and wound assessment. A rising count after several days, or fever, suggests infection.
Answer
C · A common stress response to surgery that is monitored
10.Lab values & electrolytes
Answer: C · IV hydration, a uric acid-lowering drug and frequent electrolytes
Why this is the answer
Prevention includes aggressive IV hydration, drugs such as allopurinol or rasburicase to lower uric acid, and frequent monitoring of potassium, phosphate, calcium, uric acid and creatinine. Tumor lysis usually begins within 1–3 days of starting treatment.
Answer
C · IV hydration, a uric acid-lowering drug and frequent electrolytes
11.Arterial blood gas interpretation
Answer: PaCO₂ = 23 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·10 + 8 = 23 mmHg
range: 21–25 mmHg
Answer
PaCO₂ = 23 mmHg
12.Arterial blood gas interpretation
Answer: added respiratory acidosis
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·15 + 8 = 30.5 → 28.5–32.5 mmHg
Compare
measured: 43 mmHg → added respiratory acidosis
Answer
added respiratory acidosis
13.ECG rhythm strip interpretation
Answer: supraventricular tachycardia (SVT)
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC. Narrow-complex tachycardia and pauses: supraventricular tachycardia (SVT) is a regular tachycardia at about 150–250/min with narrow QRS complexes; the P waves are usually not visible because they are hidden in the QRS complex or the T wave. Sinus tachycardia in an adult at rest is usually below about 150/min and has a visible P wave before every QRS; atrial flutter with 2:1 conduction often runs at about 150/min and shows sawtooth waves. In sinus arrest the sinus node stops firing for a moment: a pause with no P wave and no QRS whose length is not a whole number of P–P cycles (a pause of exactly two or three cycles points to sinus exit block instead).
Five steps
1. Rate: R–R = 10 small boxes, 1500 ÷ 10 ≈ 150 per minute.
2. Rhythm: regular, every R–R is 0.40 s.
3. P waves: none visible; at this rate they are hidden in the QRS complexes or the T waves.
4. PR interval: not measurable.
5. QRS: 0.06 s, narrow (below 0.12 s), so the rhythm starts above the ventricles.
Interpretation
supraventricular tachycardia (SVT)
Answer
supraventricular tachycardia (SVT)
14.ECG rhythm strip interpretation
Answer: 2:1 AV block (type undetermined)
2:1 AV block: with two P waves for every QRS, no two conducted P waves follow each other, so you cannot see whether the PR would lengthen (type I) or stay constant (type II) before a non-conducted P wave. From one strip it is called a 2:1 AV block; a longer strip or a change in the conduction ratio decides the type. A narrow QRS makes type I more likely and a wide QRS type II, but neither proves it.
Five steps
1. Rate: R–R = 38 small boxes, 1500 ÷ 38 ≈ 39 per minute.
2. Rhythm: regular, every R–R is 1.52 s.
3. P waves: upright and regular (P–P 0.76 s, 79 per minute), two for every QRS.
4. PR interval: constant at 0.18 s in the conducted beats.
5. QRS: 0.12 s, wide (0.12 s or more).
Why the type stays open
Every second P wave is not conducted, so no two conducted beats follow each other and a lengthening PR could never show.
2:1 AV block (type undetermined)
Answer
2:1 AV block (type undetermined)
A narrow QRS makes type I more likely and a wide QRS type II, but only a longer strip or a change in the conduction ratio decides.
15.Prioritization & delegation
Answer: A · “I will keep my spare insulin in the freezer so it lasts longer.”
Why this is the answer
Freezing damages insulin, and frozen insulin should not be used. Unopened insulin is kept in the fridge, and heat and expired products are avoided.
Answer
A · “I will keep my spare insulin in the freezer so it lasts longer.”
16.Prioritization & delegation
Answer: B · Flush the eye with plenty of water or saline straight away
Why this is the answer
Chemical eye injuries are treated by immediate, continuous irrigation with large amounts of water or saline. Delay, rubbing or a patch allows more damage.
Answer
B · Flush the eye with plenty of water or saline straight away