Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Why should a beta-blocker not be stopped suddenly in a patient with ischaemic heart disease?
AThe drug stays stored in the tissues for several months afterwards
CSudden stopping causes severe and prolonged hypoglycaemia
DRebound tachycardia and hypertension can trigger angina or MI
2.Med-surg: cardiovascular & respiratoryHard
A patient taking apixaban for atrial fibrillation is booked for elective surgery. Which statement reflects correct practice?
AStop it two weeks before surgery and replace it with warfarin
BIt is always continued up to the morning of the operation
CIt is stopped and then reversed with oral vitamin K
DPause it for a set time, based on bleeding risk and kidney function
3.Med-surg: neuro, endocrine & renalMedium
How does the nurse test the facial nerve (VII)?
AShine a light in each eye and check the pupil response
BTouch the forehead, cheek and chin with cotton wool
CAsk them to raise the eyebrows, shut the eyes tightly and smile
DAsk the patient to stick out the tongue and move it from side to side
4.Med-surg: neuro, endocrine & renalHard
A patient is being assessed for brain death (brainstem death). Which condition must be excluded before testing?
AEffects of sedative drugs or severe hypothermia
BA haemoglobin of 110 g/L (11 g/dL)
CA previous episode of migraine
DA history of high blood pressure
5.Med-surg: GI, perioperative & oncologyMedium
Why are antibody levels checked after a healthcare worker receives the hepatitis B vaccine?
ATo decide whether they need a liver biopsy
BTo measure liver damage caused by the vaccine
CTo confirm that the vaccine produced immunity
DTo check whether they caught hepatitis B from the vaccine
6.Med-surg: GI, perioperative & oncologyHard
A patient's long-standing groin hernia has become tender, red and irreducible, and they are vomiting. What should the nurse do?
AAdvise the patient to wear a tight truss and rest
BApply a hot water bottle and give a laxative
CPush the hernia firmly back in, then discharge home
DKeep them nil by mouth and arrange urgent surgical review
7.Clinical nursingMedium
In suspected sepsis, what should ideally be collected before the first dose of antibiotics, as long as it does not delay treatment?
AA fasting cholesterol level
BA 24-hour urine collection
CA stool sample for occult blood
DBlood cultures
8.Clinical nursingHard
An adult with capacity refuses a blood transfusion for religious reasons, even though it may save their life. What should the nurse do?
AGive the transfusion while the patient is asleep, as it is in their best interests
BRespect the refusal, check it is informed and document it, and inform the team
CSedate the patient so the transfusion can be given
DAsk a family member to consent instead
9.Lab values & electrolytesMedium
A patient has a sodium of 124 mEq/L, a headache and new confusion. Which nursing measure is most appropriate?
AKeep the patient flat and limit neurological checks to once a shift
BPut seizure precautions in place and monitor neurological status
CGive the next dose of the prescribed thiazide diuretic early
DEncourage the patient to drink plenty of plain water
10.Lab values & electrolytesHard
A patient with severe hypertriglyceridemia has a measured sodium of 128 mEq/L, but a measured serum osmolality is normal, and the patient has no symptoms. What is the most likely explanation?
APseudohyponatremia, an artifact caused by very high lipids
BHyponatremia caused by severe hyperglycemia in diabetes
CTrue hyponatremia from SIADH that needs fluid restriction
DHyponatremia caused by drinking far too much water
11.Arterial blood gas interpretationMedium
Practice values: Na⁺ 142 mmol/L, glucose 25.5 mmol/L and urea 20.1 mmol/L. Calculate the serum osmolality Osm = 2·Na⁺ + glucose + urea to the nearest whole number.
Na⁺ 142 mmol/Lglucose 25.5 mmol/Lurea 20.1 mmol/L
Osm = mOsm/kg
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.17, PaCO₂ 31 mmHg (4.1 kPa), HCO₃⁻ 11 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.17PaCO₂ 31 mmHg (4.1 kPa)HCO₃⁻ 11 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
This lead II strip shows sinus rhythm with one pause. Measure the pause, the R–R interval across it, in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
pause = s
14.ECG rhythm strip interpretationHard
Interpret this lead II strip with the five steps in order: rate, rhythm, P waves, PR interval, QRS duration. At which step do you find the first abnormal finding? Click it.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1rate
2rhythm
3P waves
4PR interval
5QRS duration
15.Prioritization & delegationMedium
Which task should the nurse delegate to a nursing assistant for a patient on fall precautions?
ADeciding whether the bed alarm is still needed
BAssessing and recording the patient’s fall risk score each morning
CHelping the patient to the toilet every 2 hours as planned
DTeaching the family how to prevent falls at home
16.Prioritization & delegationHard
A patient opens their eyes only to pain, uses inappropriate words and withdraws from pain. What is the Glasgow Coma Scale score?
A13
B7
C11
D9
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · Rebound tachycardia and hypertension can trigger angina or MI
Why this is the answer
Long-term beta-blockade increases the number and sensitivity of beta receptors. Abrupt withdrawal exposes them to normal adrenaline levels, which can cause rebound tachycardia, hypertension and myocardial ischaemia. Doses are tapered.
Answer
D · Rebound tachycardia and hypertension can trigger angina or MI
2.Med-surg: cardiovascular & respiratory
Answer: D · Pause it for a set time, based on bleeding risk and kidney function
Why this is the answer
Because DOACs wear off within days, they are usually paused for a defined period before surgery (often 1–3 days) depending on the procedure's bleeding risk and renal function; bridging with heparin is generally not needed. Vitamin K does not reverse DOACs.
Answer
D · Pause it for a set time, based on bleeding risk and kidney function
3.Med-surg: neuro, endocrine & renal
Answer: C · Ask them to raise the eyebrows, shut the eyes tightly and smile
Why this is the answer
The facial nerve moves the muscles of the face. Asking the patient to raise the eyebrows, close the eyes, puff the cheeks and smile shows any weakness. Facial sensation is carried by the trigeminal nerve.
Answer
C · Ask them to raise the eyebrows, shut the eyes tightly and smile
4.Med-surg: neuro, endocrine & renal
Answer: A · Effects of sedative drugs or severe hypothermia
Why this is the answer
Before brain death (brainstem) testing, reversible causes of coma must be excluded, including sedatives and neuromuscular blockers, hypothermia, and severe metabolic or endocrine disturbance. Only then can absent reflexes be interpreted reliably.
Answer
A · Effects of sedative drugs or severe hypothermia
5.Med-surg: GI, perioperative & oncology
Answer: C · To confirm that the vaccine produced immunity
Why this is the answer
Some people do not develop protective anti-HBs antibodies after vaccination. Testing identifies non-responders, who may need further doses and advice after exposures.
Answer
C · To confirm that the vaccine produced immunity
6.Med-surg: GI, perioperative & oncology
Answer: D · Keep them nil by mouth and arrange urgent surgical review
Why this is the answer
A tender, red, irreducible hernia with vomiting suggests strangulation and bowel obstruction. It needs emergency surgery; the nurse keeps the patient nil by mouth, gives analgesia, and starts IV access and fluids as prescribed.
Answer
D · Keep them nil by mouth and arrange urgent surgical review
7.Clinical nursing
Answer: D · Blood cultures
Why this is the answer
Blood cultures taken before antibiotics are more likely to grow the organism, which allows targeted treatment later. Antibiotics should still be given promptly and must not be delayed.
Answer
D · Blood cultures
8.Clinical nursing
Answer: B · Respect the refusal, check it is informed and document it, and inform the team
Why this is the answer
An adult with capacity has the right to refuse treatment, even life-saving treatment. The team should make sure the patient understands the consequences, discuss alternatives such as cell salvage and record the decision.
Answer
B · Respect the refusal, check it is informed and document it, and inform the team
9.Lab values & electrolytes
Answer: B · Put seizure precautions in place and monitor neurological status
Why this is the answer
Hyponatremia can cause cerebral edema and seizures. The nurse monitors neurological status, takes seizure precautions and reports the result. Extra water and thiazides can lower the sodium further.Checked against:Low blood sodium · MedlinePlus (NIH) (2025)
Answer
B · Put seizure precautions in place and monitor neurological status
10.Lab values & electrolytes
Answer: A · Pseudohyponatremia, an artifact caused by very high lipids
Why this is the answer
Very high lipids or proteins take up part of the plasma volume, so some laboratory methods report a falsely low sodium. The osmolality and the sodium measured by direct methods are normal. Treating this "hyponatremia" would be harmful.
Answer
A · Pseudohyponatremia, an artifact caused by very high lipids
11.Arterial blood gas interpretation
Answer: Osm = 330 mOsm/kg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Calculated osmolality
Osm = 2·142 + 25.5 + 20.1 = 329.6 ≈ 330 mOsm/kg
Answer
Osm = 330 mOsm/kg
12.Arterial blood gas interpretation
Answer: added respiratory acidosis
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·11 + 8 = 24.5 → 22.5–26.5 mmHg
Compare
measured: 31 mmHg → added respiratory acidosis
Answer
added respiratory acidosis
13.ECG rhythm strip interpretation
Answer: pause = 1.84 s
Narrow-complex tachycardia and pauses: supraventricular tachycardia (SVT) is a regular tachycardia at about 150–250/min with narrow QRS complexes; the P waves are usually not visible because they are hidden in the QRS complex or the T wave. Sinus tachycardia in an adult at rest is usually below about 150/min and has a visible P wave before every QRS; atrial flutter with 2:1 conduction often runs at about 150/min and shows sawtooth waves. In sinus arrest the sinus node stops firing for a moment: a pause with no P wave and no QRS whose length is not a whole number of P–P cycles (a pause of exactly two or three cycles points to sinus exit block instead).
Measure
46 small boxes from R to R across the pause
Convert
pause = 46 × 0.04 s = 1.84 s
Compare with P–P
1.84 ÷ 0.76 ≈ 2.4 P–P cycles, not a whole number
Answer
pause = 1.84 s
No P wave appears in the pause, and the pause is not a whole number of P–P cycles: sinus arrest. A pause of exactly two or three cycles would point to sinus exit block.
14.ECG rhythm strip interpretation
Answer: QRS duration
Five steps for every strip: 1. rate (300 or 1500 method, or the 6-second method if irregular); 2. rhythm: are the R–R intervals equal; 3. P waves: present, upright in lead II, one before every QRS and all alike; 4. PR interval: 0.12–0.20 s and constant; 5. QRS duration: below 0.12 s. Only after the five steps name the rhythm. Normal sinus rhythm passes all five: 60–100/min, regular, upright P before every QRS, PR 0.12–0.20 s, QRS below 0.12 s.
Five steps
1. Rate: R–R = 23 small boxes, 1500 ÷ 23 ≈ 65 per minute.
2. Rhythm: regular, every R–R is 0.92 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.14 s, constant, within 0.12–0.20 s.
5. QRS: 0.14 s, wide (0.12 s or more).
First abnormal step
QRS duration → sinus rhythm with wide QRS
Answer
QRS duration
15.Prioritization & delegation
Answer: C · Helping the patient to the toilet every 2 hours as planned
Why this is the answer
A scheduled toileting round is a routine task that follows the care plan. Scoring fall risk, deciding on interventions and teaching need nursing judgement.
Answer
C · Helping the patient to the toilet every 2 hours as planned
16.Prioritization & delegation
Answer: D · 9
Why this is the answer
Eyes open to pain scores 2, inappropriate words score 3 and withdrawal from pain scores 4, giving 9. A score of 8 or less often means the patient cannot protect their airway.