Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Two days after a myocardial infarction, a patient develops sudden breathlessness, crackles and a new loud systolic murmur. Which complication should be suspected?
APost-infarction pericarditis causing a pericardial friction rub
BPapillary muscle rupture with acute mitral regurgitation
CA pulmonary embolism caused by prolonged bed rest
DA new episode of stable angina brought on by stress
2.Med-surg: cardiovascular & respiratoryHard
A patient recovering from an MI is anxious about returning to normal life. Which intervention best supports recovery?
AReferral to cardiac rehabilitation
BAdvice to avoid all exercise permanently
CAdvice to rest in bed for three months
DAdvice to stop tablets once they feel well
3.Med-surg: neuro, endocrine & renalMedium
A conscious patient with a glucose of 3.1 mmol/L (56 mg/dL) can swallow safely. Which is the best first treatment?
AA chocolate bar and a cup of tea with milk
BA glass of milk and two plain biscuits
CA dose of rapid-acting insulin with a sandwich
DGlucose tablets or a small glass of fruit juice
4.Med-surg: neuro, endocrine & renalHard
A patient received IV insulin and glucose for hyperkalaemia an hour ago. What must the nurse monitor over the next few hours?
ACapillary glucose, for hypoglycaemia
BPupils, for raised intracranial pressure
CSkin, for a drug rash
DUrine colour, for blood in the urine
5.Med-surg: GI, perioperative & oncologyMedium
Which advice helps prevent dumping syndrome after gastrectomy?
ASmall, frequent meals low in simple sugars, with fluids between meals
BSit upright and walk briskly straight after every meal
CA high-sugar diet with fruit juice to keep energy levels up
DThree large meals a day with plenty of sweet drinks with each meal
6.Med-surg: GI, perioperative & oncologyHard
A patient with known oesophageal varices is vomiting large amounts of fresh blood. Which treatments should the nurse anticipate before endoscopy?
AOctreotide or terlipressin, plus IV antibiotics, during resuscitation
BAn urgent barium swallow before any drug treatment
COral NSAID for pain and a high-protein meal
DRapid saline infusion to a high blood pressure
7.Clinical nursingMedium
Compared with a colostomy, a patient with an ileostomy is at greater risk of:
ADehydration and electrolyte loss from liquid output
BUrinary retention
CLow blood glucose after meals
DHard stools, straining and constipation from slow transit
8.Clinical nursingHard
A patient has new facial weakness. Which feature suggests a stroke rather than Bell's palsy?
AThe patient has had a recent cold
BThe patient has pain behind the ear
CThe whole of one side of the face, including the forehead, is weak
DThe forehead can still be wrinkled on the affected side
9.Lab values & electrolytesMedium
A patient taking phenazopyridine for bladder pain has bright orange urine. What should the nurse know about urine tests?
AThe color shows severe liver failure is present
BThe dye can interfere with dipstick color readings
CThe color proves blood is present in the urine
DThe drug improves the accuracy of all dipsticks
10.Lab values & electrolytesHard
A patient with diabetes and chronic kidney disease had a CT scan with IV contrast. Two days later, the creatinine has risen from 1.4 to 2.0 mg/dL (124 to 177 µmol/L). Which action is most appropriate?
AReport it, monitor urine output and hold metformin until reviewed
BGive extra metformin, because the glucose rises after contrast
CIgnore it, because contrast never affects kidney function
DRestrict all fluids to protect the kidneys from more contrast
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 14 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 14 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
A practice gas shows a respiratory acidosis: pH 7.25, PaCO₂ 62 mmHg (8.3 kPa), HCO₃⁻ 26 mmol/L. Use the rules ‘HCO₃⁻ rises 1 mmol/L per 10 mmHg (acute) or 3.5 mmol/L per 10 mmHg (chronic)’ to classify it. Click your answer.
pH 7.25PaCO₂ 62 mmHg (8.3 kPa)HCO₃⁻ 26 mmol/L
1acute
2chronic
3acute on chronic
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1junctional rhythm
2sinus bradycardia
3sinus tachycardia
4first-degree AV block
14.ECG rhythm strip interpretationHard
Interpret this lead II strip. Which interpretation can you defend from this single strip? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1second-degree AV block type I (Wenckebach)
2sinus bradycardia
32:1 AV block (type undetermined)
4third-degree (complete) AV block
15.Prioritization & delegationMedium
A patient has a sudden nosebleed, is alert and is breathing normally. What does the nurse do first?
ASit the patient up, lean them forward and pinch the soft part of the nose
BAsk the patient to blow the nose hard to clear the clots
CLie the patient flat on their back with a pillow under the knees
DTilt the head back and apply ice to the back of the neck
16.Prioritization & delegationHard
Which patient’s finding is the most urgent?
AA patient whose platelet count result is pending
BA patient on warfarin with an INR of 2.5 who is due for the usual evening dose
CA patient on a heparin infusion who has new confusion and a severe headache
DA patient after knee surgery with a small bruise at an injection site
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · Papillary muscle rupture with acute mitral regurgitation
Why this is the answer
Rupture of a papillary muscle (or of the ventricular septum) after MI produces a new murmur and sudden heart failure or shock. This is a surgical emergency. Pericarditis causes pleuritic chest pain and a friction rub rather than acute pulmonary oedema with a new murmur.
Answer
B · Papillary muscle rupture with acute mitral regurgitation
2.Med-surg: cardiovascular & respiratory
Answer: A · Referral to cardiac rehabilitation
Why this is the answer
Cardiac rehabilitation combines supervised exercise, risk factor education, medication advice and psychological support. It improves quality of life and reduces cardiovascular mortality and readmissions. Patients are encouraged to return gradually to activity, including work, driving and sex, according to advice.
Answer
A · Referral to cardiac rehabilitation
3.Med-surg: neuro, endocrine & renal
Answer: D · Glucose tablets or a small glass of fruit juice
Why this is the answer
About 15–20 g of fast-acting carbohydrate, such as glucose tablets or juice, raises glucose quickly. Chocolate and milk contain fat, which slows absorption. Glucose is rechecked after about 15 minutes.
Answer
D · Glucose tablets or a small glass of fruit juice
4.Med-surg: neuro, endocrine & renal
Answer: A · Capillary glucose, for hypoglycaemia
Why this is the answer
Hypoglycaemia is a common complication of insulin–glucose treatment and can occur several hours later, especially in kidney failure. Glucose is checked regularly according to protocol, and potassium is rechecked.
Answer
A · Capillary glucose, for hypoglycaemia
5.Med-surg: GI, perioperative & oncology
Answer: A · Small, frequent meals low in simple sugars, with fluids between meals
Why this is the answer
Small meals, fewer simple sugars, more protein and fibre, and taking fluids between rather than with meals slow emptying and reduce fluid shifts. Lying down briefly after meals can also help.
Answer
A · Small, frequent meals low in simple sugars, with fluids between meals
6.Med-surg: GI, perioperative & oncology
Answer: A · Octreotide or terlipressin, plus IV antibiotics, during resuscitation
Why this is the answer
In suspected variceal bleeding, a vasoactive drug (octreotide in the US, or terlipressin where it is licensed) reduces portal pressure, and prophylactic antibiotics such as ceftriaxone reduce infection and mortality in cirrhosis. Resuscitation is cautious to avoid raising portal pressure. Endoscopic band ligation is the definitive treatment.
Answer
A · Octreotide or terlipressin, plus IV antibiotics, during resuscitation
7.Clinical nursing
Answer: A · Dehydration and electrolyte loss from liquid output
Why this is the answer
Ileostomy output is liquid because it bypasses the colon, which normally absorbs water and salts. Patients must drink enough and watch for signs of dehydration, especially in hot weather or illness.
Answer
A · Dehydration and electrolyte loss from liquid output
8.Clinical nursing
Answer: D · The forehead can still be wrinkled on the affected side
Why this is the answer
In a stroke (upper motor neurone lesion), the forehead is usually spared because it has bilateral cortical supply. Bell's palsy (lower motor neurone) weakens the whole side, including the forehead.
Answer
D · The forehead can still be wrinkled on the affected side
9.Lab values & electrolytes
Answer: B · The dye can interfere with dipstick color readings
Why this is the answer
Phenazopyridine is a urinary analgesic dye that turns urine orange-red. It can interfere with color-based dipstick tests, so the laboratory should be told. The color is harmless, but it can stain contact lenses and clothing.Checked against:Urine - abnormal color · MedlinePlus (NIH) (2025)
Answer
B · The dye can interfere with dipstick color readings
10.Lab values & electrolytes
Answer: A · Report it, monitor urine output and hold metformin until reviewed
Why this is the answer
A creatinine rise of 0.3 mg/dL or more within 48 hours meets the criteria for AKI, and contrast is a recognized risk factor, especially in CKD and diabetes. The nurse reports it, monitors fluid balance and holds metformin until kidney function is reviewed, as metformin can accumulate.Checked against:Acute Kidney Injury · StatPearls (NCBI Bookshelf) (2026); Abdominal CT scan · MedlinePlus (NIH) (2024); Acute kidney failure · MedlinePlus (NIH) (2026)
Answer
A · Report it, monitor urine output and hold metformin until reviewed
11.Arterial blood gas interpretation
Answer: PaCO₂ = 29 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·14 + 8 = 29 mmHg
range: 27–31 mmHg
Answer
PaCO₂ = 29 mmHg
12.Arterial blood gas interpretation
Answer: acute
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected HCO₃⁻
acute: 24 + 1·2.2 = 26.2 mmol/L
chronic: 24 + 3.5·2.2 = 31.7 mmol/L
Compare
measured: 26 mmol/L → acute
Answer
acute
13.ECG rhythm strip interpretation
Answer: first-degree AV block
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 25 small boxes, 1500 ÷ 25 ≈ 60 per minute.
2. Rhythm: regular, every R–R is 1.00 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.30 s, constant, longer than 0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
first-degree AV block
Answer
first-degree AV block
14.ECG rhythm strip interpretation
Answer: 2:1 AV block (type undetermined)
2:1 AV block: with two P waves for every QRS, no two conducted P waves follow each other, so you cannot see whether the PR would lengthen (type I) or stay constant (type II) before a non-conducted P wave. From one strip it is called a 2:1 AV block; a longer strip or a change in the conduction ratio decides the type. A narrow QRS makes type I more likely and a wide QRS type II, but neither proves it.
Five steps
1. Rate: R–R = 40 small boxes, 1500 ÷ 40 ≈ 38 per minute.
2. Rhythm: regular, every R–R is 1.60 s.
3. P waves: upright and regular (P–P 0.80 s, 75 per minute), two for every QRS.
4. PR interval: constant at 0.18 s in the conducted beats.
5. QRS: 0.12 s, wide (0.12 s or more).
Why the type stays open
Every second P wave is not conducted, so no two conducted beats follow each other and a lengthening PR could never show.
2:1 AV block (type undetermined)
Answer
2:1 AV block (type undetermined)
A narrow QRS makes type I more likely and a wide QRS type II, but only a longer strip or a change in the conduction ratio decides.
15.Prioritization & delegation
Answer: A · Sit the patient up, lean them forward and pinch the soft part of the nose
Why this is the answer
Leaning forward keeps blood out of the airway and stomach, and firm pressure on the soft part of the nose usually stops the bleeding. Tilting the head back or lying flat lets blood run into the throat.
Answer
A · Sit the patient up, lean them forward and pinch the soft part of the nose
16.Prioritization & delegation
Answer: C · A patient on a heparin infusion who has new confusion and a severe headache
Why this is the answer
New confusion and a severe headache in an anticoagulated patient may mean an intracranial bleed. An INR of 2.5 is within the common therapeutic range of 2 to 3, and a small injection-site bruise is common.
Answer
C · A patient on a heparin infusion who has new confusion and a severe headache