Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Which pneumonia severity score uses confusion, urea, respiratory rate, blood pressure and age?
ANEWS2
BCHA₂DS₂-VASc
CWells score
DCURB-65
2.Med-surg: cardiovascular & respiratoryHard
A nurse reviews inhaler use with a patient who has asthma and uses a separate steroid preventer inhaler and a salbutamol reliever. Which statement shows a need for further teaching?
A"I use my steroid inhaler when I start to wheeze."
B"I carry my blue reliever inhaler with me."
C"I rinse my mouth after the steroid inhaler."
D"I use my steroid inhaler every day, even when I feel well."
3.Med-surg: neuro, endocrine & renalMedium
Before checking a capillary glucose, why should the patient wash their hands with soap and water?
AWashing lowers the glucose in the blood
BSugar on the skin can give a falsely high reading
CSoap makes the blood flow faster from the finger
DWashing prevents all infection from the lancet
4.Med-surg: neuro, endocrine & renalHard
A patient with CKD has a high phosphate, a low calcium and a high PTH. What does this show?
ASecondary hyperparathyroidism from CKD
BHypoparathyroidism after neck surgery
CPrimary hyperparathyroidism from a tumour
DToo much vitamin D from supplements
5.Med-surg: GI, perioperative & oncologyMedium
Which advice has good evidence for reducing cancer-related fatigue?
ARegular light to moderate activity, such as walking
BAvoiding all daily activities
CDrinking several strong coffees every evening
DComplete bed rest for the whole course of treatment
6.Med-surg: GI, perioperative & oncologyHard
A patient has negative pressure wound therapy. The pump alarms and the dressing has lost its seal. What is the most appropriate action?
APack the wound with dry gauze over the foam and tape it tightly
BTurn the suction up to its maximum setting to pull the seal back
CLeave the foam in the wound without suction for several days until review
DRestore the seal; if that fails in time, change to a moist dressing
7.Clinical nursingMedium
Which is a first-line nursing measure to help prevent constipation in hospital?
ARestricting fluids to reduce urine output
BEncouraging fluids, fibre and mobility
CGiving an enema to every patient on admission
DKeeping the patient in bed
8.Clinical nursingHard
A nurse teaches a patient with hypertension about their medicines. Which statement shows a need for further teaching?
A"I'll get up slowly from sitting."
B"I'll stop my tablets once my readings are normal."
C"I'll have my blood pressure checked regularly."
D"I'll keep taking my tablets even if I feel well."
9.Lab values & electrolytesMedium
The heparin infusion rate was changed according to protocol. When is the aPTT usually rechecked?
AAbout 3 days after the change
BOnly after the infusion is stopped
CAbout 6 hours after the change
DAbout 30 minutes after the change
10.Lab values & electrolytesHard
A patient with schizophrenia drinks very large amounts of water each day. Sodium is 121 mEq/L, and the urine is very dilute (urine osmolality 70 mOsm/kg). Which explanation fits best?
AHyperosmolar hyperglycemic state
BCentral diabetes insipidus
CPrimary (psychogenic) polydipsia
DSyndrome of inappropriate ADH
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 80 mmHg (10.7 kPa). Use the rule that in chronic respiratory acidosis HCO₃⁻ rises by 3.5 mmol/L for every 10 mmHg that PaCO₂ is above 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1first-degree AV block
2sinus tachycardia
3junctional rhythm
4sinus bradycardia
14.ECG rhythm strip interpretationHard
This patient has a pacemaker. Interpret the lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1paced rhythm, failure to capture
2ventricular paced rhythm
3sinus rhythm with wide QRS
4idioventricular rhythm
15.Prioritization & delegationMedium
When making patient assignments, what should the charge nurse consider first?
AMatching each patient’s needs to staff competence
BGiving the newest staff the most complex patients
CGiving each nurse patients in rooms next to each other
DLetting staff choose the patients they prefer
16.Prioritization & delegationHard
A patient is admitted with suspected meningococcal meningitis. Which precautions are needed until treatment has been given for long enough?
AStandard precautions only
BContact precautions only
CAirborne precautions
DDroplet precautions
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · CURB-65
Why this is the answer
CURB-65 gives one point each for Confusion, Urea >7 mmol/L, Respiratory rate ≥30/min, low Blood pressure (systolic <90 or diastolic ≤60 mmHg) and age ≥65. Higher scores mean higher mortality and the need for hospital or critical care.
Answer
D · CURB-65
2.Med-surg: cardiovascular & respiratory
Answer: A · "I use my steroid inhaler when I start to wheeze."
Why this is the answer
Inhaled corticosteroids are preventers that reduce airway inflammation over days to weeks and must be taken regularly. They do not relieve an acute wheeze. Unless the patient has a combined reliever and maintenance regimen, a short-acting bronchodilator is used for symptoms.
Answer
A · "I use my steroid inhaler when I start to wheeze."
3.Med-surg: neuro, endocrine & renal
Answer: B · Sugar on the skin can give a falsely high reading
Why this is the answer
Traces of sugar on the fingers can falsely raise the reading. Hands are washed and dried before testing. The side of the fingertip is used, and lancets are single use.
Answer
B · Sugar on the skin can give a falsely high reading
4.Med-surg: neuro, endocrine & renal
Answer: A · Secondary hyperparathyroidism from CKD
Why this is the answer
In CKD, phosphate retention and low active vitamin D lower calcium, so the parathyroid glands release more PTH. This secondary hyperparathyroidism weakens bone. Treatment includes phosphate control, vitamin D and sometimes calcimimetics.
Answer
A · Secondary hyperparathyroidism from CKD
5.Med-surg: GI, perioperative & oncology
Answer: A · Regular light to moderate activity, such as walking
Why this is the answer
Exercise, matched to ability, reduces cancer-related fatigue. Pacing, prioritising activities, sleep routines and treating causes such as anaemia or depression also help.
Answer
A · Regular light to moderate activity, such as walking
6.Med-surg: GI, perioperative & oncology
Answer: D · Restore the seal; if that fails in time, change to a moist dressing
Why this is the answer
NPWT needs an airtight seal. If the seal or suction is lost and cannot be restored promptly (many guidelines say within about 2 hours), the foam is removed and replaced with a standard dressing to reduce infection risk. Manufacturer and local guidance define the safe interval.
Answer
D · Restore the seal; if that fails in time, change to a moist dressing
7.Clinical nursing
Answer: B · Encouraging fluids, fibre and mobility
Why this is the answer
Adequate fluids, a fibre-rich diet, mobility and privacy for toileting help prevent constipation. Laxatives are added if needed, especially with opioids.
Answer
B · Encouraging fluids, fibre and mobility
8.Clinical nursing
Answer: B · "I'll stop my tablets once my readings are normal."
Why this is the answer
Hypertension usually needs long-term treatment; stopping because readings are normal often makes blood pressure rise again. Patients should discuss any changes with their prescriber.
Answer
B · "I'll stop my tablets once my readings are normal."
9.Lab values & electrolytes
Answer: C · About 6 hours after the change
Why this is the answer
Most weight-based heparin protocols check the aPTT (or anti-Xa level) about 6 hours after starting or changing the rate, because it takes this long to reach a new steady state. Checking too early can lead to wrong adjustments.
Answer
C · About 6 hours after the change
10.Lab values & electrolytes
Answer: C · Primary (psychogenic) polydipsia
Why this is the answer
In primary polydipsia, ADH is appropriately suppressed, so the kidneys make very dilute urine, but the intake exceeds what they can excrete. In SIADH the urine is inappropriately concentrated. Fluid restriction and close sodium monitoring are needed.Checked against:Osmolality urine test · MedlinePlus (NIH) (2025); Syndrome of inappropriate antidiuretic hormone secretion · MedlinePlus (NIH) (2025)
Answer
C · Primary (psychogenic) polydipsia
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 38 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|80 − 40| = 40 mmHg → 4 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 + 3.5·4 = 38 mmol/L
Answer
HCO₃⁻ = 38 mmol/L
12.Arterial blood gas interpretation
Answer: AGc = 22.5 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 139 − (105 + 16) = 18
Correction for albumin
18 + 0.25·(40 − 22) = 22.5 mmol/L
Answer
AGc = 22.5 mmol/L
Above about 12 after correction: a high anion gap.
13.ECG rhythm strip interpretation
Answer: first-degree AV block
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 23 small boxes, 1500 ÷ 23 ≈ 65 per minute.
2. Rhythm: regular, every R–R is 0.92 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.30 s, constant, longer than 0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
first-degree AV block
Answer
first-degree AV block
14.ECG rhythm strip interpretation
Answer: ventricular paced rhythm
Paced rhythms: a pacemaker impulse shows as a narrow vertical pacing spike. After a ventricular spike the QRS is wide (0.12 s or more), because the impulse spreads from the lead through the muscle instead of the conduction system; with right-ventricular pacing it is often mostly negative in lead II. A spike before each P wave means atrial pacing, and a dual-chamber (AV) pacemaker shows an atrial spike and a P wave, then, after the programmed AV delay, a ventricular spike and a wide QRS. Capture means every spike is followed by a depolarisation. Failure to capture is a spike without a P wave or QRS after it; failure to sense (spikes that ignore the patient’s own beats) and failure to pace (no spike when one is due) are the other classic malfunctions.
Five steps
1. Rate: R–R = 20 small boxes, 1500 ÷ 20 ≈ 75 per minute.
2. Rhythm: regular, every R–R is 0.80 s.
3. P waves: none visible; a sharp pacing spike comes just before every QRS.
4. PR interval: not measurable.
5. QRS: 0.14 s, wide, and every spike is followed by a QRS (capture).
Interpretation
ventricular paced rhythm
Answer
ventricular paced rhythm
The paced QRS is wide by nature; do not call it a bundle branch block or a ventricular rhythm.
15.Prioritization & delegation
Answer: A · Matching each patient’s needs to staff competence
Why this is the answer
Assignments are based mainly on patient acuity and needs and on each staff member’s skills and scope. Geography and continuity of care help, but they come after safety.
Answer
A · Matching each patient’s needs to staff competence
16.Prioritization & delegation
Answer: D · Droplet precautions
Why this is the answer
Neisseria meningitidis spreads by respiratory droplets, so a surgical mask is worn within close range. Droplet precautions continue until the patient has received effective antibiotics for about 24 hours.