Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Why should chest drain tubing generally not be clamped?
AClamping makes the fluid drain out of the chest much too quickly
BClamping permanently weakens and cracks the tubing
CClamping causes the water in the seal to evaporate
DTrapped air can build up and cause a tension pneumothorax
2.Med-surg: cardiovascular & respiratoryHard
A nurse teaches a patient with heart failure who takes ramipril and spironolactone. Which statement shows a need for further teaching?
A"I will avoid ibuprofen for my joint pain."
B"I will weigh myself every morning after I go to the toilet."
C"I will use a salt substitute instead of ordinary salt."
D"I will call if I gain weight quickly or get more breathless."
3.Med-surg: neuro, endocrine & renalMedium
Which picture fits anterior cord syndrome?
AWeakness on one side and loss of pain sensation on the other side
BNormal movement but complete loss of position sense
CArms much weaker than legs after a neck injury
DLoss of movement and pain sense, with position sense kept
4.Med-surg: neuro, endocrine & renalHard
An adult stares blankly for about a minute, smacks their lips and fumbles with their clothes. Afterwards they are confused for ten minutes and remember nothing. Which seizure type fits best?
AAtonic (drop) seizure with a fall
BAbsence seizure
CMyoclonic seizure
DFocal impaired awareness seizure
5.Med-surg: GI, perioperative & oncologyMedium
What is anticipatory nausea in chemotherapy?
ANausea that starts about a week after each cycle and lasts for days
BNausea triggered by reminders of treatment before it is given
CNausea caused by low blood glucose
DNausea caused only by the smell of food
6.Med-surg: GI, perioperative & oncologyHard
A patient on an opioid PCA receives oxygen by mask. SpO₂ is 97% and the respiratory rate 11/min, but they are now hard to rouse. What should the nurse conclude?
AThe patient is simply sleeping well, as the pain is controlled
BOpioid toxicity is likely; the oxygen may be masking hypoventilation
CThe PCA dose should be increased to keep the patient comfortable
DThe patient is safe, because the oxygen saturation is normal
7.Clinical nursingMedium
A patient's fluid balance chart shows intake of 1,200 mL and output of 2,300 mL over 24 hours. What does this indicate?
AA positive fluid balance of 1,100 mL
BA negative fluid balance of 1,100 mL
CA balanced fluid status
DA positive fluid balance of 3,500 mL
8.Clinical nursingHard
A patient with severe sepsis starts bleeding from cannula sites and the gums, with a low platelet count and prolonged clotting times. What is most likely?
AHaemophilia A
BAn allergic reaction to the cannula
CVitamin C deficiency
DDisseminated intravascular coagulation
9.Lab values & electrolytesMedium
A patient is scheduled for a liver biopsy. Which laboratory results should the nurse check before the procedure?
APlatelet count and PT/INR
BSerum sodium and chloride
CTSH and free T4
DHbA1c and lipid panel
10.Lab values & electrolytesHard
An aPTT result is extremely high, but the nurse learns that the sample was taken from the arm where the heparin infusion runs. What is the best action?
AGive protamine at once to reverse the heparin
BAccept the result and halve the infusion rate
CRequest a new sample from the opposite arm before the dose is adjusted
DStop the heparin infusion permanently and inform the provider
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 12 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 12 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
A practice gas shows pH 7.33, PaCO₂ 35 mmHg (4.7 kPa) and HCO₃⁻ 18 mmol/L, with Na⁺ 136 and Cl⁻ 88 mmol/L. Use the anion gap and the delta ratio to click the best interpretation.
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1sinus bradycardia
2atrial fibrillation
3sinus rhythm with PVCs
4sinus arrhythmia
14.ECG rhythm strip interpretationHard
This patient has a pacemaker. Interpret the lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1dual-chamber (AV) paced rhythm
2idioventricular rhythm
3paced rhythm, failure to capture
4second-degree AV block type II
15.Prioritization & delegationMedium
A nursing assistant tells the RN that a patient’s IV pump is alarming. What is the best response?
A“Silence the alarm and I will check it at the end of the shift.”
B“I will come and check the pump and the IV site now.”
C“Turn the pump off and on again until it stops.”
D“Increase the rate a little so the alarm clears.”
16.Prioritization & delegationHard
A patient takes lithium. Which statement shows a need for further teaching?
A“I will take ibuprofen every day for my headaches.”
B“I will go for my blood tests as planned.”
C“I will drink enough fluid every day.”
D“I will keep my daily salt intake about the same as usual.”
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · Trapped air can build up and cause a tension pneumothorax
Why this is the answer
Clamping a drain while air is still leaking from the lung allows pressure to build in the pleural space, which can cause a tension pneumothorax. Clamping is only done briefly for specific reasons, such as changing the unit, and only as directed.
Answer
D · Trapped air can build up and cause a tension pneumothorax
2.Med-surg: cardiovascular & respiratory
Answer: C · "I will use a salt substitute instead of ordinary salt."
Why this is the answer
Many salt substitutes contain potassium chloride. With an ACE inhibitor and spironolactone, both of which raise potassium, they can cause dangerous hyperkalaemia. Daily weights, reporting rapid weight gain and avoiding NSAIDs (which cause fluid retention) are correct.
Answer
C · "I will use a salt substitute instead of ordinary salt."
3.Med-surg: neuro, endocrine & renal
Answer: D · Loss of movement and pain sense, with position sense kept
Why this is the answer
Anterior cord syndrome usually follows damage to the anterior spinal artery. Motor, pain and temperature pathways are lost below the injury, but the dorsal columns (fine touch, vibration and proprioception) at the back are spared.
Answer
D · Loss of movement and pain sense, with position sense kept
4.Med-surg: neuro, endocrine & renal
Answer: D · Focal impaired awareness seizure
Why this is the answer
Focal impaired awareness seizures often come from the temporal lobe. They last about a minute or two, with automatisms such as lip smacking and fumbling, and are followed by confusion. Absence seizures are shorter and have no postictal phase.
Answer
D · Focal impaired awareness seizure
5.Med-surg: GI, perioperative & oncology
Answer: B · Nausea triggered by reminders of treatment before it is given
Why this is the answer
Anticipatory nausea is a conditioned response after previous poorly controlled nausea, triggered by sights or smells linked to treatment. Good antiemetic control from the first cycle helps prevent it; relaxation techniques and anxiolytics may help.
Answer
B · Nausea triggered by reminders of treatment before it is given
6.Med-surg: GI, perioperative & oncology
Answer: B · Opioid toxicity is likely; the oxygen may be masking hypoventilation
Why this is the answer
Supplemental oxygen can keep SpO₂ normal while CO₂ rises from hypoventilation. Increasing sedation is an early sign of opioid toxicity. The nurse stops the PCA, stimulates the patient, calls for help and follows the naloxone protocol, monitoring respiratory rate, depth and sedation closely.
Answer
B · Opioid toxicity is likely; the oxygen may be masking hypoventilation
7.Clinical nursing
Answer: B · A negative fluid balance of 1,100 mL
Why this is the answer
1,200 − 2,300 = −1,100 mL. A negative balance means more fluid is lost than gained, which may cause dehydration.
Answer
B · A negative fluid balance of 1,100 mL
8.Clinical nursing
Answer: D · Disseminated intravascular coagulation
Why this is the answer
In DIC, widespread activation of clotting consumes platelets and clotting factors, causing both small clots and bleeding. Treating the underlying cause and replacing blood products as needed are key.
Answer
D · Disseminated intravascular coagulation
9.Lab values & electrolytes
Answer: A · Platelet count and PT/INR
Why this is the answer
Liver biopsy carries a risk of bleeding, and liver disease often lowers platelets and clotting factors. Platelets and PT/INR are checked beforehand, and abnormal results are reported so they can be corrected or the procedure postponed.Checked against:Liver biopsy · MedlinePlus (NIH) (2025)
Answer
A · Platelet count and PT/INR
10.Lab values & electrolytes
Answer: C · Request a new sample from the opposite arm before the dose is adjusted
Why this is the answer
Blood drawn from the infusion arm contains heparin from the drip, so the aPTT is falsely high. A sample from the other arm gives a true result. Changing the dose on a false result could cause clotting.Checked against:Partial Thromboplastin Time (PTT) Test · MedlinePlus (NIH) (2026)
Answer
C · Request a new sample from the opposite arm before the dose is adjusted
11.Arterial blood gas interpretation
Answer: PaCO₂ = 26 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·12 + 8 = 26 mmHg
range: 24–28 mmHg
Answer
PaCO₂ = 26 mmHg
12.Arterial blood gas interpretation
Answer: added metabolic alkalosis
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 136 − (88 + 18) = 30
Delta ratio
(30 − 12)/(24 − 18) = 3
added metabolic alkalosis
Answer
added metabolic alkalosis
13.ECG rhythm strip interpretation
Answer: sinus arrhythmia
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: 7 QRS complexes in 6 s, × 10 = 70 per minute.
2. Rhythm: irregular, R–R from 0.78 to 1.10 s, lengthening and shortening gradually.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.14 s, constant, within 0.12–0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
sinus arrhythmia
Answer
sinus arrhythmia
14.ECG rhythm strip interpretation
Answer: paced rhythm, failure to capture
Paced rhythms: a pacemaker impulse shows as a narrow vertical pacing spike. After a ventricular spike the QRS is wide (0.12 s or more), because the impulse spreads from the lead through the muscle instead of the conduction system; with right-ventricular pacing it is often mostly negative in lead II. A spike before each P wave means atrial pacing, and a dual-chamber (AV) pacemaker shows an atrial spike and a P wave, then, after the programmed AV delay, a ventricular spike and a wide QRS. Capture means every spike is followed by a depolarisation. Failure to capture is a spike without a P wave or QRS after it; failure to sense (spikes that ignore the patient’s own beats) and failure to pace (no spike when one is due) are the other classic malfunctions.
Five steps
1. Rate: 5 QRS complexes in 6 s, × 10 = 50 per minute.
2. Rhythm: the pacing spikes are regular (every 0.80 s), but the R–R is not, because a QRS is missing after some spikes.
3. P waves: none visible.
4. PR interval: not measurable.
5. QRS: 0.14 s and wide after the captured spikes; 2 spikes are not followed by a QRS (no capture).
Interpretation
paced rhythm, failure to capture
Answer
paced rhythm, failure to capture
Failure to capture: the pacemaker fires but the heart does not respond. Textbooks treat it as urgent to report, because the patient may depend on the pacemaker.
15.Prioritization & delegation
Answer: B · “I will come and check the pump and the IV site now.”
Why this is the answer
An alarm may mean an occlusion, air in the line or infiltration. The nurse checks the pump and site; the assistant should not adjust the pump or silence alarms.
Answer
B · “I will come and check the pump and the IV site now.”
16.Prioritization & delegation
Answer: A · “I will take ibuprofen every day for my headaches.”
Why this is the answer
NSAIDs such as ibuprofen can raise lithium levels and cause toxicity. Steady fluid and salt intake and regular blood tests help keep levels safe.
Answer
A · “I will take ibuprofen every day for my headaches.”