Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient with an implantable cardioverter-defibrillator asks what to do if it fires. Which teaching is correct?
ARemove the device battery at home if it fires more than once
BDrive straight to hospital alone after any shock so the device can be checked by the team
CIgnore any shock at all, because the device is designed to fire every day and needs no follow-up
DOne shock and well: contact the device clinic; repeated shocks or unwell: call emergency services
2.Med-surg: cardiovascular & respiratoryHard
A patient with lung cancer develops swelling of the face and arms, distended neck and chest veins and breathlessness that is worse when bending forward. What is the most likely cause?
ARight-sided heart failure
BSuperior vena cava obstruction
CAn allergic reaction to chemotherapy
DA deep vein thrombosis in the leg
3.Med-surg: neuro, endocrine & renalMedium
A patient taking warfarin is diagnosed with an intracerebral haemorrhage. What is the priority treatment?
ADoubling the warfarin dose to stabilise the INR
BStarting aspirin to prevent further clots
CIV thrombolysis within 4.5 hours
DUrgent reversal of the anticoagulant effect
4.Med-surg: neuro, endocrine & renalHard
A patient with CKD has a potassium of 6.5 mmol/L. Which medicine combination is the most likely contributor?
AParacetamol (acetaminophen), omeprazole and senna
BAmlodipine, simvastatin and aspirin
CRamipril, spironolactone and trimethoprim
DFurosemide, salbutamol and insulin
5.Med-surg: GI, perioperative & oncologyMedium
Which nursing intervention best reduces preoperative anxiety?
ATelling the patient that there is nothing to worry about
BExplaining what will happen and answering questions
CKeeping family members away until after surgery
DAvoiding talking about the operation at all
6.Med-surg: GI, perioperative & oncologyHard
A patient with gastric outlet obstruction has vomited repeatedly for several days. Which blood picture is most likely?
AHigh chloride, high potassium and metabolic acidosis
BLow chloride, low potassium and metabolic alkalosis
CNormal electrolytes with respiratory alkalosis
DHigh calcium, high sodium and respiratory acidosis
7.Clinical nursingMedium
A nurse suspects that an older patient is being financially abused by a relative. What should the nurse do?
AWait until the patient has been discharged
BConfront the relative directly at the bedside about it
CKeep it secret because it is a family matter
DRaise the concern through the local safeguarding (adult protection) procedure
8.Clinical nursingHard
A patient on metformin with reduced kidney function is due a CT scan with IV contrast. Why might metformin be withheld?
AMetformin causes severe bleeding during scans
BMetformin makes the images blurry
CMetformin reacts with the contrast to cause severe hyperglycaemia
DThere is a risk of lactic acidosis if kidney function worsens
9.Lab values & electrolytesMedium
How does IV calcium gluconate help a patient with severe hyperkalemia?
AIt increases potassium excretion by the kidneys
BIt stabilizes heart cell membranes without lowering potassium
CIt binds potassium in the gut so that it is passed in the stool
DIt moves potassium from the blood into the cells
10.Lab values & electrolytesHard
A patient on lithium has had vomiting and diarrhea for 3 days and has been taking ibuprofen. They now have a coarse tremor and confusion. The lithium level is 2.2 mEq/L. What is the best interpretation and action?
AIbuprofen side effects only; give it with food
BA low level; ask for the lithium dose to be raised
CA normal level; continue lithium as prescribed
DLithium toxicity; hold lithium and report urgently
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 10 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 10 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
Practice values: Na⁺ 136, Cl⁻ 104, HCO₃⁻ 14 mmol/L and albumin 27 g/L. Find the albumin-corrected anion gap AGc = AG + 0.25·(40 − albumin).
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial fibrillation
2atrial flutter, 2:1 conduction
3atrial flutter, 4:1 conduction
4sinus arrhythmia
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial flutter, 2:1 conduction
2atrial fibrillation
3ventricular tachycardia
4supraventricular tachycardia (SVT)
15.Prioritization & delegationMedium
On a mixed medical unit, which patient should the nurse see first?
AA patient with a mild tension headache who is asking for acetaminophen
BA patient with depression who has given away his belongings and has a suicide plan
CA patient with hypertension whose blood pressure is 136/84 mmHg
DA patient asking for written information about tomorrow’s discharge
16.Prioritization & delegationHard
Two call lights go on at the same time. One patient has pain of 7/10 after surgery. The other is a confused patient at high risk of falls who is climbing out of bed alone. Who does the nurse go to first?
AWhichever patient’s room is closer to the station
BThe patient in pain after surgery
CThe patient whose call light went on first
DThe confused patient climbing out of bed
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · One shock and well: contact the device clinic; repeated shocks or unwell: call emergency services
Why this is the answer
A single shock with full recovery usually needs a call to the device team. Several shocks in a short time, or a shock with chest pain, breathlessness or collapse, needs emergency help. Patients should not drive themselves after a shock.
Answer
D · One shock and well: contact the device clinic; repeated shocks or unwell: call emergency services
2.Med-surg: cardiovascular & respiratory
Answer: B · Superior vena cava obstruction
Why this is the answer
A tumour in the mediastinum can compress the superior vena cava, causing swelling of the face, neck and arms, dilated veins on the chest and breathlessness. It is an oncological emergency. The patient is sat upright and given oxygen if hypoxic, and treatment may include a stent, steroids or radiotherapy.
Answer
B · Superior vena cava obstruction
3.Med-surg: neuro, endocrine & renal
Answer: D · Urgent reversal of the anticoagulant effect
Why this is the answer
Anticoagulants make the haematoma expand. Warfarin is reversed urgently, typically with prothrombin complex concentrate and IV vitamin K. Thrombolysis and antiplatelets are contraindicated in a bleed.
Answer
D · Urgent reversal of the anticoagulant effect
4.Med-surg: neuro, endocrine & renal
Answer: C · Ramipril, spironolactone and trimethoprim
Why this is the answer
ACE inhibitors and spironolactone reduce aldosterone effect, and trimethoprim blocks potassium secretion in the distal tubule. Together, in CKD, they can cause dangerous hyperkalaemia. Loop diuretics, salbutamol and insulin lower potassium.
Answer
C · Ramipril, spironolactone and trimethoprim
5.Med-surg: GI, perioperative & oncology
Answer: B · Explaining what will happen and answering questions
Why this is the answer
Clear information about what to expect, including pain control and recovery, reduces anxiety and can improve recovery. False reassurance does not address the patient's concerns.
Answer
B · Explaining what will happen and answering questions
6.Med-surg: GI, perioperative & oncology
Answer: B · Low chloride, low potassium and metabolic alkalosis
Why this is the answer
Loss of gastric acid causes a hypochloraemic metabolic alkalosis. Hypokalaemia follows from vomiting and kidney potassium loss as the body tries to save volume. Treatment includes IV saline with potassium.
Answer
B · Low chloride, low potassium and metabolic alkalosis
7.Clinical nursing
Answer: D · Raise the concern through the local safeguarding (adult protection) procedure
Why this is the answer
Financial abuse is a form of adult abuse. Nurses report concerns through safeguarding procedures, document facts accurately and involve the patient as appropriate.
Answer
D · Raise the concern through the local safeguarding (adult protection) procedure
8.Clinical nursing
Answer: D · There is a risk of lactic acidosis if kidney function worsens
Why this is the answer
Iodinated contrast can worsen kidney function, and metformin can then accumulate and cause lactic acidosis. Local policy guides when to stop and restart it.
Answer
D · There is a risk of lactic acidosis if kidney function worsens
9.Lab values & electrolytes
Answer: B · It stabilizes heart cell membranes without lowering potassium
Why this is the answer
Calcium counteracts the effect of high potassium on the heart’s electrical activity within minutes. The potassium must still be lowered by shifting it into cells (insulin with glucose) and removing it (binders, diuretics or dialysis).Checked against:High potassium level · MedlinePlus (NIH) (2025)
Answer
B · It stabilizes heart cell membranes without lowering potassium
10.Lab values & electrolytes
Answer: D · Lithium toxicity; hold lithium and report urgently
Why this is the answer
A level of 2.2 mEq/L with coarse tremor and confusion is lithium toxicity. Fluid loss and NSAIDs both reduce lithium excretion by the kidneys. The dose is held, the provider is informed at once, and fluids and close monitoring are expected; severe cases may need dialysis.
Answer
D · Lithium toxicity; hold lithium and report urgently
11.Arterial blood gas interpretation
Answer: PaCO₂ = 23 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·10 + 8 = 23 mmHg
range: 21–25 mmHg
Answer
PaCO₂ = 23 mmHg
12.Arterial blood gas interpretation
Answer: AGc = 21.25 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 136 − (104 + 14) = 18
Correction for albumin
18 + 0.25·(40 − 27) = 21.25 mmol/L
Answer
AGc = 21.25 mmol/L
Above about 12 after correction: a high anion gap.
13.ECG rhythm strip interpretation
Answer: atrial fibrillation
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: 8 QRS complexes in 6 s, × 10 = 80 per minute.
2. Rhythm: irregularly irregular, R–R from 0.54 to 1.04 s with no pattern.
3. P waves: none; the baseline shows small irregular fibrillatory waves.
4. PR interval: not measurable.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
atrial fibrillation
Answer
atrial fibrillation
14.ECG rhythm strip interpretation
Answer: ventricular tachycardia
Ventricular rhythms: ventricular tachycardia is a run of three or more wide (0.12 s or more) complexes in a row at more than 100/min, usually 150–250/min, regular, without related P waves. Ventricular fibrillation is a chaotic, irregular waveform with no identifiable P waves, QRS complexes or T waves and no countable rate. Asystole is an almost flat line with no ventricular activity; a flat line is always confirmed by checking the patient, the leads and the gain and a second lead. In resuscitation guidelines VF and pulseless VT are the shockable rhythms and asystole is not.
Five steps
1. Rate: R–R = 10 small boxes, 1500 ÷ 10 ≈ 150 per minute.
2. Rhythm: regular, every R–R is 0.40 s.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: 0.14 s, wide (0.12 s or more).
Interpretation
ventricular tachycardia
Answer
ventricular tachycardia
In resuscitation guidelines VF and pulseless VT are the shockable rhythms. This is identification practice only.
15.Prioritization & delegation
Answer: B · A patient with depression who has given away his belongings and has a suicide plan
Why this is the answer
Giving away belongings and having a plan are warning signs of suicide, an immediate safety threat. The other patients are stable and their needs can wait.
Answer
B · A patient with depression who has given away his belongings and has a suicide plan
16.Prioritization & delegation
Answer: D · The confused patient climbing out of bed
Why this is the answer
A confused patient climbing out of bed could fall and be badly injured within moments. Pain needs prompt treatment, but the immediate safety risk comes first.