Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A woman with hypertension who takes lisinopril says she is planning a pregnancy. What should the nurse advise?
ADouble the dose to protect the baby from high blood pressure
BDiscuss switching medicine with the prescriber before trying to conceive
CContinue lisinopril, as it is the safest blood pressure drug in pregnancy
DStop all blood pressure treatment straight away without telling anyone
2.Med-surg: cardiovascular & respiratoryHard
An 84-year-old with heart failure becomes breathless with new crackles and a rising blood pressure during a blood transfusion. What should the nurse suspect?
ATransfusion-associated circulatory overload
BNormal effects of the transfusion
CAn acute haemolytic reaction from wrong blood
DA mild febrile reaction
3.Med-surg: neuro, endocrine & renalMedium
A patient with diabetic neuropathy has an ulcer on the ball of the foot. Which measure is most important for healing?
AWalking more to improve blood flow
BTaking pressure off the ulcer
CSoaking the foot in hot water daily
DCovering it and checking it in a month
4.Med-surg: neuro, endocrine & renalHard
A patient's potassium is 7.1 mmol/L, and the ECG shows peaked T waves and broad QRS complexes. What is the first treatment?
AIV calcium gluconate
BOral potassium binder
CIV furosemide
DOral sodium bicarbonate
5.Med-surg: GI, perioperative & oncologyMedium
Which task for a stable patient with an established ileostomy can usually be delegated to a trained healthcare assistant (nursing assistant)?
ADeciding whether IV fluids are needed
BEmptying the pouch and measuring the output
CTeaching the patient about high-output risks
DAssessing the stoma for signs of necrosis
6.Med-surg: GI, perioperative & oncologyHard
Which new prescription for a patient with cirrhosis should the nurse question?
ALactulose to keep the bowels open
BThiamine supplements
CRegular ibuprofen for back pain
DSpironolactone for ascites
7.Clinical nursingMedium
A nurse gives a patient analgesia for post-operative pain. What should be done next?
AAssume the pain has gone if the patient is quiet and has their eyes closed
BGive a second analgesic straight away just in case
CWait until the next shift before asking the patient about the pain
DReassess the pain and any side effects once the drug has had time to work
8.Clinical nursingHard
A patient with type 1 diabetes is nil by mouth before surgery. Why must their insulin not simply be stopped?
AWithout any insulin they can develop diabetic ketoacidosis
BStopping insulin causes immediate hypoglycaemia during the operation
CInsulin prevents wound infection on its own
DInsulin is needed for the anaesthetic to work
9.Lab values & electrolytesMedium
A patient with chronic kidney disease receives an erythropoiesis-stimulating agent such as epoetin alfa. Which assessments are most important?
ALiver enzymes and bilirubin
BSerum glucose and ketones
CSerum amylase and lipase
DHemoglobin and blood pressure
10.Lab values & electrolytesHard
A patient with long-term heavy alcohol use is admitted with alcohol withdrawal. Which group of electrolyte problems is most common?
AHigh sodium, high calcium and high glucose
BHigh magnesium, high phosphate and high potassium
CLow magnesium, low phosphate and low potassium
DLow chloride, high bicarbonate and high calcium
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.51, PaCO₂ 31 mmHg (4.1 kPa) and HCO₃⁻ 24 mmol/L. The primary disorder is respiratory alkalosis. How far is it compensated? Click your answer.
pH 7.51PaCO₂ 31 mmHg (4.1 kPa)HCO₃⁻ 24 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
Practice values: Na⁺ 140, Cl⁻ 108, HCO₃⁻ 16 mmol/L and albumin 16 g/L. Find the albumin-corrected anion gap AGc = AG + 0.25·(40 − albumin).
This lead II strip shows atrial flutter with a fixed conduction ratio. Find the ventricular rate in beats per minute.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
ventricular rate = bpm
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial flutter, 4:1 conduction
2torsades de pointes
3ventricular fibrillation
4ventricular tachycardia
15.Prioritization & delegationMedium
A patient has a serum potassium of 2.9 mEq/L. Which finding should the nurse expect?
ATall, peaked T waves and muscle twitching
BMuscle weakness and U waves on the ECG
CA rise in urine output and thirst only
DFlushed, warm skin and a slow heart rate
16.Prioritization & delegationHard
A nursing assistant measured vital signs 15 minutes after a patient’s first dose of morphine. They report a respiratory rate of 10/min and say the patient is hard to wake. What should the nurse do?
AAsk the assistant to recheck the respiratory rate in 15 minutes and report back
BPhone the provider for orders before going to see the patient
CDocument the findings and tell the provider at the next scheduled round
DGo at once, rouse the patient, support breathing and prepare naloxone per order
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · Discuss switching medicine with the prescriber before trying to conceive
Why this is the answer
ACE inhibitors and ARBs are contraindicated in pregnancy because they can damage fetal kidneys and cause other harm. Women of childbearing age should be counselled and switched to a suitable alternative, such as labetalol or nifedipine, before conception or as soon as pregnancy is confirmed.
Answer
B · Discuss switching medicine with the prescriber before trying to conceive
2.Med-surg: cardiovascular & respiratory
Answer: A · Transfusion-associated circulatory overload
Why this is the answer
Transfusion-associated circulatory overload causes breathlessness, crackles, raised BP and JVP during or soon after transfusion, especially in older people and those with heart or kidney disease. The transfusion is stopped or slowed, the patient sat up and given oxygen, and diuretics may be prescribed. Slow rates and single units with reassessment reduce the risk.
Answer
A · Transfusion-associated circulatory overload
3.Med-surg: neuro, endocrine & renal
Answer: B · Taking pressure off the ulcer
Why this is the answer
Offloading (removing pressure) is essential for healing a neuropathic ulcer, along with infection control, good blood supply and specialist foot team care. Hot soaks risk burns because sensation is reduced.
Answer
B · Taking pressure off the ulcer
4.Med-surg: neuro, endocrine & renal
Answer: A · IV calcium gluconate
Why this is the answer
ECG changes mean the heart is at risk. IV calcium is given first to stabilise the myocardium, followed by insulin with glucose (and often nebulised salbutamol) to shift potassium into cells. Binders or dialysis then remove it.
Answer
A · IV calcium gluconate
5.Med-surg: GI, perioperative & oncology
Answer: B · Emptying the pouch and measuring the output
Why this is the answer
Emptying and measuring output is a routine task. Assessment of the stoma, teaching and decisions about treatment remain with the registered nurse, who reviews the recorded output.
Answer
B · Emptying the pouch and measuring the output
6.Med-surg: GI, perioperative & oncology
Answer: C · Regular ibuprofen for back pain
Why this is the answer
NSAIDs can cause kidney injury, fluid retention and GI bleeding in cirrhosis and should be avoided. Paracetamol at a reduced, carefully reviewed dose is usually preferred for pain.
Answer
C · Regular ibuprofen for back pain
7.Clinical nursing
Answer: D · Reassess the pain and any side effects once the drug has had time to work
Why this is the answer
The effect of analgesia should be reassessed when it is expected to work, with side effects such as sedation and breathing checked. The result is documented and the plan adjusted.
Answer
D · Reassess the pain and any side effects once the drug has had time to work
8.Clinical nursing
Answer: A · Without any insulin they can develop diabetic ketoacidosis
Why this is the answer
People with type 1 diabetes make no insulin, so stopping it causes ketosis and DKA. Basal insulin is usually continued, often with a variable-rate insulin infusion and glucose monitoring.
Answer
A · Without any insulin they can develop diabetic ketoacidosis
9.Lab values & electrolytes
Answer: D · Hemoglobin and blood pressure
Why this is the answer
Epoetin stimulates red cell production. Hemoglobin is monitored, because raising it too high increases the risk of hypertension, stroke and thrombosis. Blood pressure is monitored, and iron stores are checked, since iron is needed for a good response.Checked against:Erythropoietin Stimulating Agents · StatPearls (NCBI Bookshelf) (2024)
Answer
D · Hemoglobin and blood pressure
10.Lab values & electrolytes
Answer: C · Low magnesium, low phosphate and low potassium
Why this is the answer
Poor diet, vomiting, diarrhea and alcohol's effect on the kidneys commonly cause low magnesium, phosphate and potassium. These worsen arrhythmia and seizure risk, so they are checked and replaced, together with thiamine.
Answer
C · Low magnesium, low phosphate and low potassium
11.Arterial blood gas interpretation
Answer: uncompensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.51: alkalaemia (above 7.45)
PaCO₂ 31 mmHg: low (35–45)
HCO₃⁻ 24 mmol/L: normal (22–26)
Compensation
uncompensated
Answer
uncompensated
12.Arterial blood gas interpretation
Answer: AGc = 22 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 140 − (108 + 16) = 16
Correction for albumin
16 + 0.25·(40 − 16) = 22 mmol/L
Answer
AGc = 22 mmol/L
Above about 12 after correction: a high anion gap.
13.ECG rhythm strip interpretation
Answer: ventricular rate = 63 bpm
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Flutter waves
F–F = 6 small boxes = 0.24 s → 1500 ÷ 6 = 250 per minute
QRS complexes
R–R = 24 small boxes = 0.96 s → 1500 ÷ 24 = 63 per minute
conduction ratio = 250 ÷ 63 = 4:1
Answer
ventricular rate = 63 bpm
14.ECG rhythm strip interpretation
Answer: ventricular fibrillation
Ventricular rhythms: ventricular tachycardia is a run of three or more wide (0.12 s or more) complexes in a row at more than 100/min, usually 150–250/min, regular, without related P waves. Ventricular fibrillation is a chaotic, irregular waveform with no identifiable P waves, QRS complexes or T waves and no countable rate. Asystole is an almost flat line with no ventricular activity; a flat line is always confirmed by checking the patient, the leads and the gain and a second lead. In resuscitation guidelines VF and pulseless VT are the shockable rhythms and asystole is not.
Five steps
1. Rate: no countable ventricular rate.
2. Rhythm: chaotic, no repeating pattern.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: no QRS complexes.
Interpretation
ventricular fibrillation
Answer
ventricular fibrillation
In resuscitation guidelines VF and pulseless VT are the shockable rhythms. This is identification practice only.
15.Prioritization & delegation
Answer: B · Muscle weakness and U waves on the ECG
Why this is the answer
Hypokalemia causes muscle weakness, cramps and arrhythmias, with flattened T waves and U waves on the ECG. Peaked T waves are a sign of hyperkalemia.
Answer
B · Muscle weakness and U waves on the ECG
16.Prioritization & delegation
Answer: D · Go at once, rouse the patient, support breathing and prepare naloxone per order
Why this is the answer
Slow breathing and difficulty rousing suggest opioid-induced respiratory depression. The nurse assesses the patient straight away, stimulates them, supports breathing, gives naloxone per order and escalates. Waiting or calling without seeing the patient wastes critical minutes.
Answer
D · Go at once, rouse the patient, support breathing and prepare naloxone per order