Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
What is pulmonary rehabilitation in COPD?
AA lung function test repeated every six months
BSupervised exercise and education that ease breathlessness
CSurgery to remove the most damaged areas of lung
DA course of oral steroids and antibiotics given at home each winter
2.Med-surg: cardiovascular & respiratoryHard
During a cardiac arrest, the monitor shows an organised rhythm, but there is no pulse. What should the team do?
AContinue CPR and give adrenaline (epinephrine), as the rhythm is non-shockable
BStop CPR, because an organised rhythm on the monitor means recovery
CGive adenosine to slow the rhythm down
DDeliver an unsynchronised shock at once and then check the pulse
3.Med-surg: neuro, endocrine & renalMedium
A patient with untreated hyperthyroidism is losing weight. Which diet is most appropriate until the condition is controlled?
AA low-calorie diet to protect the heart
BA diet very high in caffeine for energy
CA high-calorie diet with enough protein
DA strict low-protein diet
4.Med-surg: neuro, endocrine & renalHard
A patient with a subarachnoid haemorrhage develops a low sodium. Why is fluid restriction usually avoided in this patient?
ALow blood volume can worsen vasospasm and brain ischaemia
BLow sodium in this condition always corrects itself
CFluid restriction raises the risk of seizures
DFluid restriction would cause the aneurysm to re-bleed
5.Med-surg: GI, perioperative & oncologyMedium
Which advice helps a person with diabetes prevent foot ulcers?
ASoak the feet in very hot water every evening
BCut corns off at home with a sharp blade
CWear tight shoes to support the ankles
DCheck the feet every day and never walk barefoot
6.Med-surg: GI, perioperative & oncologyHard
A patient with recurrent diverticulitis reports passing air and faecal matter in the urine. What is the most likely cause?
AA kidney stone blocking the ureter
BBowel preparation that was taken too quickly
CA fistula between the colon and the bladder
DA simple lower urinary tract infection
7.Clinical nursingMedium
Which blood results are typical of Addison's disease (primary adrenal insufficiency)?
ALow sodium and high potassium
BHigh glucose and high calcium
CHigh sodium and low potassium
DLow haemoglobin and high platelets
8.Clinical nursingHard
A patient with a central venous catheter needs the line removed. Which position reduces the risk of air embolism during removal of a neck or chest line?
ALying on the right side with the legs raised
BStanding up and walking
CLying flat or slightly head-down, holding the breath or breathing out
DSitting fully upright and taking a deep breath in as the line comes out
9.Lab values & electrolytesMedium
After pituitary surgery, a patient passes about 400 mL of pale urine per hour with a specific gravity of 1.002, and the sodium has risen to 149 mEq/L. Which condition is most likely?
ADiabetes insipidus
BAcute kidney injury with oliguria
CSIADH
DHyperglycemia with ketoacidosis
10.Lab values & electrolytesHard
A patient on long-term amiodarone has fatigue and weight gain. TSH is 11 mIU/L and the free T4 is low. What is the most likely explanation?
AAmiodarone-induced hypothyroidism
BSecondary hypothyroidism from pituitary failure
CAmiodarone-induced hyperthyroidism
DA normal response to amiodarone needing no action
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 23 mmHg (3.1 kPa). Use the rule that in chronic respiratory alkalosis HCO₃⁻ falls by 5 mmol/L for every 10 mmHg that PaCO₂ is below 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
A practice gas shows a metabolic alkalosis with HCO₃⁻ 39 mmol/L. Use expected PaCO₂ = 0.7·HCO₃⁻ + 21 to find the expected PaCO₂.
HCO₃⁻ 39 mmol/L
PaCO₂ = mmHg
13.ECG rhythm strip interpretationMedium
This lead II strip shows sinus rhythm with one pause. Measure the pause, the R–R interval across it, in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
pause = s
14.ECG rhythm strip interpretationHard
This patient has a pacemaker. Interpret the lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1dual-chamber (AV) paced rhythm
2paced rhythm, failure to capture
3ventricular paced rhythm
4sinus rhythm with wide QRS
15.Prioritization & delegationMedium
A patient is receiving a blood transfusion. Which task can the nurse delegate to a nursing assistant?
ADeciding whether to stop the transfusion if the patient has chills
BAssessing the patient for signs of a transfusion reaction
CMeasuring and reporting vital signs at the times set by the nurse
DStarting the transfusion once the blood arrives
16.Prioritization & delegationHard
Which patient finding after a total knee replacement needs the nurse’s action first?
AA small amount of dried blood on the dressing
BPain of 4/10 when the physiotherapist bends the knee during the morning session
CSudden calf pain and swelling in the operated leg, with new breathlessness
DAsks for an ice pack to help with swelling around the knee
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · Supervised exercise and education that ease breathlessness
Why this is the answer
Pulmonary rehabilitation combines individually tailored exercise training, education and breathing techniques. It improves exercise capacity, breathlessness and quality of life and reduces hospital admissions. It is recommended for people with COPD who are limited by breathlessness and after an exacerbation.
Answer
B · Supervised exercise and education that ease breathlessness
2.Med-surg: cardiovascular & respiratory
Answer: A · Continue CPR and give adrenaline (epinephrine), as the rhythm is non-shockable
Why this is the answer
Pulseless electrical activity is a non-shockable rhythm. Treatment is high-quality CPR, adrenaline as soon as possible and repeated, and a search for reversible causes (the 4 Hs and 4 Ts, such as hypoxia, hypovolaemia, tension pneumothorax and tamponade). Shocks are only for VF and pulseless VT.
Answer
A · Continue CPR and give adrenaline (epinephrine), as the rhythm is non-shockable
3.Med-surg: neuro, endocrine & renal
Answer: C · A high-calorie diet with enough protein
Why this is the answer
Excess thyroid hormone raises metabolism, so patients need more calories and protein to prevent weight loss. Caffeine is limited because it worsens palpitations, tremor and anxiety.
Answer
C · A high-calorie diet with enough protein
4.Med-surg: neuro, endocrine & renal
Answer: A · Low blood volume can worsen vasospasm and brain ischaemia
Why this is the answer
Hyponatraemia after subarachnoid haemorrhage may come from SIADH or cerebral salt wasting. Restricting fluid can cause hypovolaemia, which makes delayed cerebral ischaemia more likely. Sodium is usually corrected with fluids or salt under specialist advice.
Answer
A · Low blood volume can worsen vasospasm and brain ischaemia
5.Med-surg: GI, perioperative & oncology
Answer: D · Check the feet every day and never walk barefoot
Why this is the answer
Peripheral neuropathy and poor circulation mean injuries can go unnoticed. Daily inspection, well-fitting footwear, checking water temperature and regular podiatry help prevent ulcers.
Answer
D · Check the feet every day and never walk barefoot
6.Med-surg: GI, perioperative & oncology
Answer: C · A fistula between the colon and the bladder
Why this is the answer
Pneumaturia and faecaluria suggest a colovesical fistula, a recognised complication of diverticulitis (and Crohn's disease or cancer). Recurrent urinary infections are common, and surgery is usually needed.
Answer
C · A fistula between the colon and the bladder
7.Clinical nursing
Answer: A · Low sodium and high potassium
Why this is the answer
Without aldosterone, the kidneys lose sodium and retain potassium. Patients may also have low blood pressure, low glucose and increased skin pigmentation.
Answer
A · Low sodium and high potassium
8.Clinical nursing
Answer: C · Lying flat or slightly head-down, holding the breath or breathing out
Why this is the answer
A flat or head-down position and a Valsalva manoeuvre or breath-hold raise central venous pressure, reducing the risk of air being drawn in. An occlusive dressing is then applied.
Answer
C · Lying flat or slightly head-down, holding the breath or breathing out
9.Lab values & electrolytes
Answer: A · Diabetes insipidus
Why this is the answer
Surgery near the pituitary can stop the release of antidiuretic hormone. Without it, the kidneys pass large volumes of dilute urine with a low specific gravity, and the sodium rises. SIADH is the opposite: concentrated urine and a low sodium. The nurse measures intake and output closely and reports early.Checked against:Diabetes insipidus · MedlinePlus (NIH) (2025); Urine specific gravity test · MedlinePlus (NIH) (2025); Sodium blood test · MedlinePlus (NIH) (2025)
Answer
A · Diabetes insipidus
10.Lab values & electrolytes
Answer: A · Amiodarone-induced hypothyroidism
Why this is the answer
Amiodarone is rich in iodine and can cause either hypothyroidism or hyperthyroidism. A high TSH with a low free T4 shows primary hypothyroidism, so thyroid function is monitored before and during therapy; liver tests are monitored too.Checked against:Hypothyroidism · MedlinePlus (NIH) (2024)
Answer
A · Amiodarone-induced hypothyroidism
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 15.5 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|23 − 40| = 17 mmHg → 1.7 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 − 5·1.7 = 15.5 mmol/L
Answer
HCO₃⁻ = 15.5 mmol/L
12.Arterial blood gas interpretation
Answer: PaCO₂ = 48.3 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
0.7·39 + 21 = 48.3 mmHg
Answer
PaCO₂ = 48.3 mmHg
The rise has a limit: PaCO₂ rarely goes above about 55 mmHg from compensation alone.
13.ECG rhythm strip interpretation
Answer: pause = 2.04 s
Narrow-complex tachycardia and pauses: supraventricular tachycardia (SVT) is a regular tachycardia at about 150–250/min with narrow QRS complexes; the P waves are usually not visible because they are hidden in the QRS complex or the T wave. Sinus tachycardia in an adult at rest is usually below about 150/min and has a visible P wave before every QRS; atrial flutter with 2:1 conduction often runs at about 150/min and shows sawtooth waves. In sinus arrest the sinus node stops firing for a moment: a pause with no P wave and no QRS whose length is not a whole number of P–P cycles (a pause of exactly two or three cycles points to sinus exit block instead).
Measure
51 small boxes from R to R across the pause
Convert
pause = 51 × 0.04 s = 2.04 s
Compare with P–P
2.04 ÷ 0.88 ≈ 2.3 P–P cycles, not a whole number
Answer
pause = 2.04 s
No P wave appears in the pause, and the pause is not a whole number of P–P cycles: sinus arrest. A pause of exactly two or three cycles would point to sinus exit block.
14.ECG rhythm strip interpretation
Answer: ventricular paced rhythm
Paced rhythms: a pacemaker impulse shows as a narrow vertical pacing spike. After a ventricular spike the QRS is wide (0.12 s or more), because the impulse spreads from the lead through the muscle instead of the conduction system; with right-ventricular pacing it is often mostly negative in lead II. A spike before each P wave means atrial pacing, and a dual-chamber (AV) pacemaker shows an atrial spike and a P wave, then, after the programmed AV delay, a ventricular spike and a wide QRS. Capture means every spike is followed by a depolarisation. Failure to capture is a spike without a P wave or QRS after it; failure to sense (spikes that ignore the patient’s own beats) and failure to pace (no spike when one is due) are the other classic malfunctions.
Five steps
1. Rate: R–R = 24 small boxes, 1500 ÷ 24 ≈ 63 per minute.
2. Rhythm: regular, every R–R is 0.96 s.
3. P waves: none visible; a sharp pacing spike comes just before every QRS.
4. PR interval: not measurable.
5. QRS: 0.14 s, wide, and every spike is followed by a QRS (capture).
Interpretation
ventricular paced rhythm
Answer
ventricular paced rhythm
The paced QRS is wide by nature; do not call it a bundle branch block or a ventricular rhythm.
15.Prioritization & delegation
Answer: C · Measuring and reporting vital signs at the times set by the nurse
Why this is the answer
An assistant can measure vital signs and report them. Assessing for a reaction, starting the transfusion and deciding to stop it need the nurse’s judgement.
Answer
C · Measuring and reporting vital signs at the times set by the nurse
16.Prioritization & delegation
Answer: C · Sudden calf pain and swelling in the operated leg, with new breathlessness
Why this is the answer
Calf pain and swelling suggest deep vein thrombosis, and new breathlessness raises concern for a pulmonary embolism. This needs immediate assessment and escalation; the other findings are expected.
Answer
C · Sudden calf pain and swelling in the operated leg, with new breathlessness