Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Which history is a contraindication to thrombolysis for a STEMI?
AA previous appendicectomy many years ago
BA previous haemorrhagic stroke
CMild asthma controlled with inhalers
DTreated high blood pressure
2.Med-surg: cardiovascular & respiratoryHard
Ten days after cardiac surgery, a patient has a fever, a red sternal wound with discharge and a clicking feeling in the chest when coughing. What should the nurse suspect?
ASternal wound infection with an unstable sternum
BCostochondritis caused by forceful coughing
CPericarditis from the operation
DNormal wound healing with some expected discharge
3.Med-surg: neuro, endocrine & renalMedium
A patient with primary adrenal insufficiency has a fever. What is the usual sick-day advice for steroid replacement?
AStop the steroid until the fever has settled
BHalve the dose to reduce the side effects
CIncrease the glucocorticoid dose, often doubling it
DKeep the usual dose and avoid drinking extra fluids for now
4.Med-surg: neuro, endocrine & renalHard
A patient on haemodialysis is on a medical ward. Which task can the registered nurse delegate to a healthcare assistant (nursing assistant)?
AAssessing the thrill and bruit of the fistula
BDeciding which morning medicines to hold
CTeaching the patient about fluid restriction
DWeighing the patient before they go to dialysis
5.Med-surg: GI, perioperative & oncologyMedium
Which approach to red cell transfusion in a stable patient with a GI bleed fits current evidence?
AA restrictive threshold, often around 70 g/L, in most stable patients
BTransfuse everyone to keep the haemoglobin above 150 g/L at all times
CNever transfuse, whatever the haemoglobin or the symptoms
DTransfuse two units routinely before every endoscopy
6.Med-surg: GI, perioperative & oncologyHard
A 60 kg adult with 25% TBSA burns arrives 2 hours after the injury, having had no IV fluids. Using the Parkland formula, what hourly rate is needed for the rest of the first 8 hours?
A375 mL/h
B1000 mL/h
C500 mL/h
D250 mL/h
7.Clinical nursingMedium
During an IV infusion, the area around the cannula becomes swollen, cool and pale, and the infusion slows. What is likely?
AAir embolism
BFluid overload of the circulation
CInfiltration of fluid into the surrounding tissue
DPhlebitis caused by bacterial infection of the vein wall
8.Clinical nursingHard
An older man has sudden severe abdominal and back pain, is hypotensive and has a pulsating mass in the abdomen. What should be suspected?
AAcute gastritis from anti-inflammatory drugs
BA ruptured abdominal aortic aneurysm
CRenal colic from a kidney stone
DMusculoskeletal back pain
9.Lab values & electrolytesMedium
A patient with a potassium of 2.8 mEq/L has potassium chloride prescribed IV. Which statement about giving it is correct?
AIt is given as an undiluted bolus into a large vein to avoid irritation
BIt is added to the IV bag without mixing, so it stays at the bottom
CIt is always diluted and given by infusion pump, never as an IV push
DIt may be given as a slow IV push over one minute if the level is very low
10.Lab values & electrolytesHard
A patient with a platelet count of 35 × 10³/µL is prescribed an intramuscular injection. What should the nurse do?
AGive the injection and apply a heat pack
BGive the injection with a longer needle
CAsk the prescriber whether another route can be used
DGive the injection as prescribed and massage the site firmly
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.15, PaCO₂ 21 mmHg (2.8 kPa) and HCO₃⁻ 7 mmol/L. The primary disorder is metabolic acidosis. How far is it compensated? Click your answer.
pH 7.15PaCO₂ 21 mmHg (2.8 kPa)HCO₃⁻ 7 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
At sea level, a practice gas taken on 35% oxygen shows PaO₂ 55 mmHg (7.3 kPa) and PaCO₂ 58 mmHg (7.7 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial fibrillation
2atrial flutter, 4:1 conduction
3sinus arrhythmia
4sinus rhythm with PVCs
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1asystole
2sinus bradycardia
3third-degree (complete) AV block
4ventricular fibrillation
15.Prioritization & delegationMedium
A patient taking lisinopril develops swelling of the lips and tongue. What should the nurse do first?
AApply a cold pack and recheck in an hour
BAssess the airway and call for urgent help
CTell the patient this is a common, harmless effect
DGive the next dose of lisinopril with water
16.Prioritization & delegationHard
A patient has full-thickness burns all the way around the chest and is finding it harder to breathe, although the airway is clear. What does this suggest?
AThe patient is anxious and only needs reassurance
BThe burns are healing and the skin is tightening normally
CThe patient has had too little IV fluid and needs a fast bolus to improve the breathing
DThe tight burned skin is restricting chest movement, so an escharotomy may be needed
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · A previous haemorrhagic stroke
Why this is the answer
Absolute contraindications include any previous intracranial haemorrhage, recent ischaemic stroke, active internal bleeding, suspected aortic dissection and recent major trauma or surgery. Thrombolysis is used when primary PCI cannot be delivered in time.
Answer
B · A previous haemorrhagic stroke
2.Med-surg: cardiovascular & respiratory
Answer: A · Sternal wound infection with an unstable sternum
Why this is the answer
Deep sternal wound infection and sternal dehiscence are serious complications, more common with diabetes, obesity and COPD. Signs include fever, wound discharge, redness and an unstable or clicking sternum. Urgent surgical review, wound swabs, blood cultures and antibiotics are needed.
Answer
A · Sternal wound infection with an unstable sternum
3.Med-surg: neuro, endocrine & renal
Answer: C · Increase the glucocorticoid dose, often doubling it
Why this is the answer
During illness, people on steroid replacement need more glucocorticoid. Sick-day rules usually advise doubling the dose during fever and using emergency injectable hydrocortisone or seeking urgent care if they vomit and cannot keep tablets down, to prevent adrenal crisis.
Answer
C · Increase the glucocorticoid dose, often doubling it
4.Med-surg: neuro, endocrine & renal
Answer: D · Weighing the patient before they go to dialysis
Why this is the answer
Weighing a patient is a routine task suitable for a trained assistant. Assessing the access, making medication decisions and teaching require the registered nurse's knowledge and judgement.
Answer
D · Weighing the patient before they go to dialysis
5.Med-surg: GI, perioperative & oncology
Answer: A · A restrictive threshold, often around 70 g/L, in most stable patients
Why this is the answer
Restrictive transfusion (often at a haemoglobin of about 70 g/L, with a target of 70–90 g/L, or a higher threshold in cardiovascular disease) is associated with better outcomes in many GI bleeding patients than liberal transfusion. Massive haemorrhage is managed by major haemorrhage protocols.
Answer
A · A restrictive threshold, often around 70 g/L, in most stable patients
6.Med-surg: GI, perioperative & oncology
Answer: C · 500 mL/h
Why this is the answer
Parkland gives 4 × 60 × 25 = 6000 mL in 24 hours, with 3000 mL due in the first 8 hours from the time of injury. With 6 hours left, 3000 ÷ 6 = 500 mL/h. Dividing by 8 (375 mL/h) ignores the delay. The rate is then adjusted to urine output.
Answer
C · 500 mL/h
7.Clinical nursing
Answer: C · Infiltration of fluid into the surrounding tissue
Why this is the answer
Infiltration causes cool, swollen, pale skin. Stop the infusion and remove the cannula. If the fluid is a vesicant, this is extravasation and needs specific management.
Answer
C · Infiltration of fluid into the surrounding tissue
8.Clinical nursing
Answer: B · A ruptured abdominal aortic aneurysm
Why this is the answer
A ruptured AAA classically presents with pain, shock and a pulsatile mass. It is a surgical emergency needing immediate senior help and transfer to theatre.
Answer
B · A ruptured abdominal aortic aneurysm
9.Lab values & electrolytes
Answer: C · It is always diluted and given by infusion pump, never as an IV push
Why this is the answer
Concentrated potassium chloride given as an IV push can cause fatal cardiac arrest, so it is never pushed. It is diluted, mixed well and given by infusion pump at a rate set by protocol, often with cardiac monitoring at higher rates.
Answer
C · It is always diluted and given by infusion pump, never as an IV push
10.Lab values & electrolytes
Answer: C · Ask the prescriber whether another route can be used
Why this is the answer
IM injections can cause bleeding into the muscle when platelets are low. The nurse asks for another route, such as oral or IV. If an injection is unavoidable, firm pressure without massage is applied afterwards.Checked against:Bleeding and Bruising (Thrombocytopenia) and Cancer Treatment · National Cancer Institute (NIH) (2022)
Answer
C · Ask the prescriber whether another route can be used
11.Arterial blood gas interpretation
Answer: partially compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.15: acidaemia (below 7.35)
PaCO₂ 21 mmHg: low (35–45)
HCO₃⁻ 7 mmol/L: low (22–26)
Compensation
Clinically, also check the expected compensation: Winter’s formula expects PaCO₂ 16.5–20.5 mmHg, so the measured 21 mmHg points to an additional respiratory acidosis (a mixed disorder). The answer above is the ROME exam classification.
partially compensated
Answer
partially compensated
12.Arterial blood gas interpretation
Answer: A–a gradient = 122 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: 8 QRS complexes in 6 s, × 10 = 80 per minute.
2. Rhythm: irregularly irregular, R–R from 0.58 to 0.96 s with no pattern.
3. P waves: none; the baseline shows small irregular fibrillatory waves.
4. PR interval: not measurable.
5. QRS: 0.10 s, narrow (below 0.12 s).
Interpretation
atrial fibrillation
Answer
atrial fibrillation
14.ECG rhythm strip interpretation
Answer: asystole
Ventricular rhythms: ventricular tachycardia is a run of three or more wide (0.12 s or more) complexes in a row at more than 100/min, usually 150–250/min, regular, without related P waves. Ventricular fibrillation is a chaotic, irregular waveform with no identifiable P waves, QRS complexes or T waves and no countable rate. Asystole is an almost flat line with no ventricular activity; a flat line is always confirmed by checking the patient, the leads and the gain and a second lead. In resuscitation guidelines VF and pulseless VT are the shockable rhythms and asystole is not.
Five steps
1. Rate: no countable ventricular rate.
2. Rhythm: none; an almost flat line.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: no QRS complexes.
Interpretation
asystole
Answer
asystole
A flat line is always checked: look at the patient, the leads and the gain, and view a second lead, because a loose electrode or fine VF can look like asystole.
15.Prioritization & delegation
Answer: B · Assess the airway and call for urgent help
Why this is the answer
Angioedema is a rare but dangerous effect of ACE inhibitors. The airway comes first: the nurse assesses breathing, calls for urgent help and holds the drug.
Answer
B · Assess the airway and call for urgent help
16.Prioritization & delegation
Answer: D · The tight burned skin is restricting chest movement, so an escharotomy may be needed
Why this is the answer
Circumferential full-thickness burns form stiff eschar that can stop the chest expanding. An escharotomy, cutting through the eschar, may be needed urgently to allow breathing.
Answer
D · The tight burned skin is restricting chest movement, so an escharotomy may be needed