Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Why are beta-blockers often started after a myocardial infarction?
AThey lower the heart's oxygen demand and reduce arrhythmias
BThey raise the heart rate to improve blood flow to the muscle
CThey reduce cholesterol in the blood
DThey dissolve the clot that is blocking the coronary artery
2.Med-surg: cardiovascular & respiratoryHard
A patient with pneumonia on high-flow nasal oxygen at 50 L/min with FiO₂ 0.6 has SpO₂ 90%, RR 34/min and is using accessory muscles. What is the most appropriate action?
AContinue the same support and recheck in four hours
BEscalate urgently to critical care for review of respiratory support
CLay the patient flat so they can rest the breathing muscles
DChange to a nasal cannula at 4 L/min to reduce nasal dryness
3.Med-surg: neuro, endocrine & renalMedium
A patient with diabetic neuropathy has an ulcer on the ball of the foot. Which measure is most important for healing?
ATaking pressure off the ulcer
BCovering it and checking it in a month
CSoaking the foot in hot water daily
DWalking more to improve blood flow
4.Med-surg: neuro, endocrine & renalHard
A nurse teaches a patient with Hashimoto's thyroiditis about levothyroxine. Which statement shows a need for further teaching?
A"I will report palpitations or chest pain."
B"I will have regular blood tests to check my dose."
C"I will take the tablets at the same time each day."
D"I can stop the tablets once I feel back to normal."
5.Med-surg: GI, perioperative & oncologyMedium
Why are antiemetics usually given before chemotherapy starts?
AAntiemetics make the chemotherapy work better
BPreventing nausea works better than treating it later
CThey cannot be given once nausea has started
DThey stop the chemotherapy from causing hair loss and mouth sores
6.Med-surg: GI, perioperative & oncologyHard
A patient's ileostomy output is 2.5 L a day. They feel tired and dizzy and are drinking large amounts of water. Which advice is usually appropriate?
AStop all drinking for 24 hours
BEat only fruit and fruit juice
CDrink even more plain water and tea to replace the losses
DLimit plain drinks and use an oral rehydration solution
7.Clinical nursingMedium
During an IV infusion, the area around the cannula becomes swollen, cool and pale, and the infusion slows. What is likely?
AFluid overload of the circulation
BPhlebitis caused by bacterial infection of the vein wall
CAir embolism
DInfiltration of fluid into the surrounding tissue
8.Clinical nursingHard
A nurse teaches a patient with reflux disease. Which statement shows a need for further teaching?
A"A big meal just before bed is fine if I take my tablet."
B"I will try to lose some weight over the next months."
C"I will cut down on alcohol."
D"I will raise the head of my bed with blocks."
9.Lab values & electrolytesMedium
A patient starts high-dose prednisone. Which laboratory change should the nurse expect?
AA rise in serum potassium
BA rise in blood glucose
CA fall in the white cell count
DA fall in serum sodium
10.Lab values & electrolytesHard
A patient's results: sodium 140 mEq/L, chloride 100 mEq/L, bicarbonate 12 mEq/L. What is the anion gap, and what does it suggest?
A12 mEq/L, a normal anion gap
B52 mEq/L, a very high anion gap
C28 mEq/L, a high anion gap
D40 mEq/L, a high anion gap
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.64, PaCO₂ 23 mmHg (3.1 kPa) and HCO₃⁻ 24 mmol/L. The primary disorder is respiratory alkalosis. How far is it compensated? Click your answer.
pH 7.64PaCO₂ 23 mmHg (3.1 kPa)HCO₃⁻ 24 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
Practice values: Na⁺ 141, Cl⁻ 110, HCO₃⁻ 15 mmol/L and albumin 30 g/L. Find the albumin-corrected anion gap AGc = AG + 0.25·(40 − albumin).
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Bazett’s formula QTc = QT/√RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1junctional rhythm
2sinus bradycardia
3third-degree (complete) AV block
4idioventricular rhythm
15.Prioritization & delegationMedium
A drowsy patient who has just returned from surgery starts to vomit. What should the nurse do first?
AGive an oral anti-sickness tablet
BRaise the legs above the heart
CGive a drink of water
DTurn the patient onto their side
16.Prioritization & delegationHard
A patient is admitted with suspected meningococcal meningitis. Which precautions are needed until treatment has been given for long enough?
AAirborne precautions
BContact precautions only
CStandard precautions only
DDroplet precautions
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · They lower the heart's oxygen demand and reduce arrhythmias
Why this is the answer
Beta-blockers slow the heart and reduce contractility, lowering myocardial oxygen demand, and protect against arrhythmias. They are particularly beneficial when the ejection fraction is reduced. They are used cautiously in heart block, severe bradycardia, acute heart failure and asthma.
Answer
A · They lower the heart's oxygen demand and reduce arrhythmias
2.Med-surg: cardiovascular & respiratory
Answer: B · Escalate urgently to critical care for review of respiratory support
Why this is the answer
High oxygen requirements with tachypnoea and increased work of breathing despite high-flow oxygen indicate worsening respiratory failure. Early critical care review is needed for escalation such as CPAP, NIV or intubation. Reducing support or waiting risks a respiratory arrest.
Answer
B · Escalate urgently to critical care for review of respiratory support
3.Med-surg: neuro, endocrine & renal
Answer: A · Taking pressure off the ulcer
Why this is the answer
Offloading (removing pressure) is essential for healing a neuropathic ulcer, along with infection control, good blood supply and specialist foot team care. Hot soaks risk burns because sensation is reduced.
Answer
A · Taking pressure off the ulcer
4.Med-surg: neuro, endocrine & renal
Answer: D · "I can stop the tablets once I feel back to normal."
Why this is the answer
In Hashimoto's thyroiditis the gland is permanently damaged, so levothyroxine is usually lifelong. Feeling well shows that the dose is right, not that the disease is cured. Stopping causes symptoms to return.
Answer
D · "I can stop the tablets once I feel back to normal."
5.Med-surg: GI, perioperative & oncology
Answer: B · Preventing nausea works better than treating it later
Why this is the answer
Chemotherapy-induced nausea and vomiting is better prevented than treated. Antiemetics are given before treatment and regularly afterwards, according to how emetogenic the regimen is.
Answer
B · Preventing nausea works better than treating it later
6.Med-surg: GI, perioperative & oncology
Answer: D · Limit plain drinks and use an oral rehydration solution
Why this is the answer
In high-output stomas, hypotonic drinks increase sodium loss through the stoma. Restricting them and using a glucose–salt oral rehydration solution, with antimotility drugs as prescribed and medical review, helps correct dehydration.
Answer
D · Limit plain drinks and use an oral rehydration solution
7.Clinical nursing
Answer: D · Infiltration of fluid into the surrounding tissue
Why this is the answer
Infiltration causes cool, swollen, pale skin. Stop the infusion and remove the cannula. If the fluid is a vesicant, this is extravasation and needs specific management.
Answer
D · Infiltration of fluid into the surrounding tissue
8.Clinical nursing
Answer: A · "A big meal just before bed is fine if I take my tablet."
Why this is the answer
Large late meals increase reflux even when a PPI is taken. Raising the head of the bed, losing weight and reducing alcohol are correct measures.
Answer
A · "A big meal just before bed is fine if I take my tablet."
9.Lab values & electrolytes
Answer: B · A rise in blood glucose
Why this is the answer
Glucocorticoids raise blood glucose by increasing glucose production and reducing insulin sensitivity. They also tend to lower potassium, retain sodium and raise the white cell count by releasing neutrophils into the blood.
Answer
B · A rise in blood glucose
10.Lab values & electrolytes
Answer: C · 28 mEq/L, a high anion gap
Why this is the answer
The anion gap is 140 − (100 + 12) = 28 mEq/L; a typical normal value is about 8–12 mEq/L when potassium is not included. A high anion gap metabolic acidosis suggests unmeasured acids, for example ketones in DKA or lactate in shock.
Answer
C · 28 mEq/L, a high anion gap
11.Arterial blood gas interpretation
Answer: uncompensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.64: alkalaemia (above 7.45)
PaCO₂ 23 mmHg: low (35–45)
HCO₃⁻ 24 mmol/L: normal (22–26)
Compensation
uncompensated
Answer
uncompensated
12.Arterial blood gas interpretation
Answer: AGc = 18.5 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 141 − (110 + 15) = 16
Correction for albumin
16 + 0.25·(40 − 30) = 18.5 mmol/L
Answer
AGc = 18.5 mmol/L
Above about 12 after correction: a high anion gap.
13.ECG rhythm strip interpretation
Answer: QTc = 0.491 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 9.5 × 0.04 = 0.38 s
RR = 15 × 0.04 = 0.60 s
Bazett’s formula
QTc = 0.38/√0.60 = 0.38/0.7746 = 0.491 s
Answer
QTc = 0.491 s
Above the usual limits for both men (about 0.45 s) and women (about 0.46 s): prolonged. (491 ms)
14.ECG rhythm strip interpretation
Answer: idioventricular rhythm
More ventricular rhythms: torsades de pointes is a polymorphic ventricular tachycardia, usually 150–250/min, in which the wide complexes change in height and twist around the baseline, pointing up for a few beats and then down. Textbooks link it to a prolonged QT interval, and magnesium sulfate is the drug resuscitation guidelines name for it. An idioventricular rhythm is a ventricular escape rhythm: regular, wide QRS (0.12 s or more), no P waves, at 20–40/min (an accelerated idioventricular rhythm runs at 40–100/min). Monomorphic VT has identical wide complexes at more than 100/min. VF is chaotic, without any repeating complex.
Five steps
1. Rate: R–R = 46 small boxes, 1500 ÷ 46 ≈ 33 per minute.
2. Rhythm: regular, every R–R is 1.84 s.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: 0.16 s, wide (0.12 s or more) and bizarre, with the T wave pointing the other way.
Interpretation
idioventricular rhythm
Answer
idioventricular rhythm
An idioventricular rhythm is an escape rhythm: the ventricles take over because the pacemakers above them have failed.
15.Prioritization & delegation
Answer: D · Turn the patient onto their side
Why this is the answer
A drowsy patient who vomits can aspirate. Turning them to the side lets vomit drain from the mouth; suction and a prescribed antiemetic follow.
Answer
D · Turn the patient onto their side
16.Prioritization & delegation
Answer: D · Droplet precautions
Why this is the answer
Neisseria meningitidis spreads by respiratory droplets, so a surgical mask is worn within close range. Droplet precautions continue until the patient has received effective antibiotics for about 24 hours.