Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A peripheral cannula site is red, warm, tender and swollen along the vein. What should the nurse do?
ARemove the cannula, document and monitor the site
BFlush the cannula hard to clear it
CLeave it in place, as this is normal after 24 hours
DCover the site and keep using it until it blocks
2.Med-surg: cardiovascular & respiratoryHard
A nurse has four cardiac patients. Which one should be seen first?
AA patient with heart failure whose weight is 0.3 kg up on yesterday's morning weight
BA patient with angina whose chest pain has not eased with rest and who is sweating
CA patient after a radial angiogram asking when they can eat
DA patient with AF and a heart rate of 86/min who is due an apixaban dose this morning
3.Med-surg: neuro, endocrine & renalMedium
Which statement about the PSA blood test is correct?
AIt can be raised by benign problems as well as by cancer
BA raised result always means prostate cancer
CIt is only raised in women with bladder cancer
DA normal result always rules out any prostate cancer
4.Med-surg: neuro, endocrine & renalHard
A woman with epilepsy who takes valproate says she is planning a pregnancy. Which response is most appropriate?
ASuggest doubling the dose to protect the baby from seizures
BTell her to stop taking the valproate completely from today
CAdvise not stopping it suddenly and urgent specialist review
DReassure her that valproate is safe throughout pregnancy
5.Med-surg: GI, perioperative & oncologyMedium
A nasogastric feeding tube appears blocked. What is usually the first step?
AFlush gently with warm water in a 50 mL enteral syringe
BUse a small 5 mL syringe with firm pressure
CCut the end of the tube to release the blockage inside it
DPush the guidewire back in to clear it
6.Med-surg: GI, perioperative & oncologyHard
While a central line is disconnected, a patient suddenly becomes breathless with chest pain and hypotension. Air embolism is suspected. What should the nurse do first?
AGive the patient a drink and observe for an hour
BSit the patient fully upright and flush the line
CRemove the central line straight away and leave the site open to the air
DClamp the line, lie the patient left side down, head low; give oxygen
7.Clinical nursingMedium
Why are people with diabetes advised to have regular eye screening?
ATo check whether they need reading glasses for close work
BTo detect diabetic retinopathy early, before sight is lost
CTo prevent conjunctivitis
DTo measure their blood glucose through the eye
8.Clinical nursingHard
Which action is most important in protecting a patient with severe neutropenia from infection?
ATaking rectal temperatures regularly
BStrict hand hygiene by everyone who has contact with the patient
CKeeping fresh flowers and plants in the room to help the patient's mood
DGiving routine intramuscular injections
9.Lab values & electrolytesMedium
A patient had a right mastectomy with removal of axillary lymph nodes. Where is the best place to draw blood?
AThe right hand
BEither arm equally
CThe right arm
DThe left arm
10.Lab values & electrolytesHard
A patient with cirrhosis and ascites has fever and abdominal tenderness. The ascitic fluid neutrophil count is 400 cells/mm³. What does this indicate?
AMalignant ascites from cancer
BBleeding into the abdominal cavity
CNormal ascitic fluid in cirrhosis
DSpontaneous bacterial peritonitis
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 20 mmHg (2.7 kPa). Use the rule that in acute respiratory alkalosis HCO₃⁻ falls by 2 mmol/L for every 10 mmHg that PaCO₂ is below 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
At sea level, a practice gas taken on 21% oxygen shows PaO₂ 87 mmHg (11.6 kPa) and PaCO₂ 38 mmHg (5.1 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
This lead II strip shows atrial flutter. How many flutter waves per QRS complex are there (the n of n:1 conduction)?
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
flutter waves per QRS =
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1third-degree (complete) AV block
2second-degree AV block type II
3sinus bradycardia
4second-degree AV block type I (Wenckebach)
15.Prioritization & delegationMedium
Which SBAR recommendation is the clearest?
A“I will keep watching him and call again tomorrow.”
B“I just wanted to let you know about him.”
C“I would like you to see him within 15 minutes and consider a fluid bolus.”
D“He seems a bit off tonight, so maybe you could come up and do something about it.”
16.Prioritization & delegationHard
After cardiac surgery, a patient becomes hypotensive with distended neck veins and muffled heart sounds, and chest drain output has suddenly stopped. What should the nurse suspect?
ALeft-sided heart failure
BCardiac tamponade
CA blocked urinary catheter
DHypovolemic shock from dehydration
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · Remove the cannula, document and monitor the site
Why this is the answer
Redness, pain, warmth and swelling along the vein indicate phlebitis. The cannula is removed, the site is observed for infection and the event is documented. Regular visual phlebitis scoring and removing cannulas that are no longer needed reduce the risk.
Answer
A · Remove the cannula, document and monitor the site
2.Med-surg: cardiovascular & respiratory
Answer: B · A patient with angina whose chest pain has not eased with rest and who is sweating
Why this is the answer
Chest pain that does not settle with rest, especially with sweating, suggests an acute coronary syndrome and needs immediate assessment and a 12-lead ECG. A controlled heart rate in AF, a very small weight change and a question about eating are not urgent.
Answer
B · A patient with angina whose chest pain has not eased with rest and who is sweating
3.Med-surg: neuro, endocrine & renal
Answer: A · It can be raised by benign problems as well as by cancer
Why this is the answer
PSA can rise with BPH, prostatitis, UTI, recent ejaculation or instrumentation, as well as cancer. A normal level does not exclude cancer. Results are interpreted with symptoms, examination and other tests.
Answer
A · It can be raised by benign problems as well as by cancer
4.Med-surg: neuro, endocrine & renal
Answer: C · Advise not stopping it suddenly and urgent specialist review
Why this is the answer
Valproate is highly teratogenic (neural tube defects and neurodevelopmental problems), and its use in people who could become pregnant is tightly restricted. However, stopping antiseizure medication suddenly risks status epilepticus. Urgent specialist review to plan a safer alternative, plus folic acid supplementation, is needed.
Answer
C · Advise not stopping it suddenly and urgent specialist review
5.Med-surg: GI, perioperative & oncology
Answer: A · Flush gently with warm water in a 50 mL enteral syringe
Why this is the answer
Gentle flushing with warm water using a 50 mL enteral syringe may clear a blockage. Small syringes and force can rupture the tube, and reinserting a guidewire can perforate the oesophagus.
Answer
A · Flush gently with warm water in a 50 mL enteral syringe
6.Med-surg: GI, perioperative & oncology
Answer: D · Clamp the line, lie the patient left side down, head low; give oxygen
Why this is the answer
Air can enter an open central line. Clamping stops more air entering; the left lateral, head-down position may keep air in the right heart away from the pulmonary outflow. High-flow oxygen and emergency help are given.
Answer
D · Clamp the line, lie the patient left side down, head low; give oxygen
7.Clinical nursing
Answer: B · To detect diabetic retinopathy early, before sight is lost
Why this is the answer
Diabetic retinopathy often has no symptoms until it is advanced. Screening allows early treatment that can prevent blindness.
Answer
B · To detect diabetic retinopathy early, before sight is lost
8.Clinical nursing
Answer: B · Strict hand hygiene by everyone who has contact with the patient
Why this is the answer
Hand hygiene is the single most effective measure to protect neutropenic patients. Rectal procedures and IM injections are avoided because they can cause mucosal or tissue injury and bleeding.
Answer
B · Strict hand hygiene by everyone who has contact with the patient
9.Lab values & electrolytes
Answer: D · The left arm
Why this is the answer
After axillary node removal, venipuncture and blood pressure readings are usually avoided on that side to reduce the risk of lymphedema and infection. The opposite arm is used whenever possible, according to policy.
Answer
D · The left arm
10.Lab values & electrolytes
Answer: D · Spontaneous bacterial peritonitis
Why this is the answer
An ascitic neutrophil count of 250 cells/mm³ or more indicates spontaneous bacterial peritonitis, which is treated with antibiotics. It can occur without classic signs, so new confusion or worsening kidney function in cirrhosis should also prompt a diagnostic paracentesis.Checked against:Ascites · MedlinePlus (NIH) (2024); Peritonitis · MedlinePlus (NIH) (2026)
Answer
D · Spontaneous bacterial peritonitis
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 20 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|20 − 40| = 20 mmHg → 2 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 − 2·2 = 20 mmol/L
Answer
HCO₃⁻ = 20 mmol/L
12.Arterial blood gas interpretation
Answer: A–a gradient = 15.23 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Flutter waves
F–F = 5 small boxes = 0.20 s → 1500 ÷ 5 = 300 per minute
QRS complexes
R–R = 20 small boxes = 0.80 s → 1500 ÷ 20 = 75 per minute
conduction ratio = 300 ÷ 75 = 4:1
Answer
flutter waves per QRS = 4
14.ECG rhythm strip interpretation
Answer: second-degree AV block type II
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: 5 QRS complexes in 6 s, × 10 = 50 per minute.
2. Rhythm: the P waves are regular; R–R is regular except for a long pause where a QRS is missing.
3. P waves: upright and regular (P–P 0.96 s, 63 per minute); one P in every 4 is not followed by a QRS.
4. PR interval: constant at 0.20 s in the conducted beats.
5. QRS: 0.12 s, wide (0.12 s or more).
Interpretation
second-degree AV block type II
Answer
second-degree AV block type II
Type II and third-degree blocks are the ones that can suddenly progress, so textbooks rank them as more serious than type I.
15.Prioritization & delegation
Answer: C · “I would like you to see him within 15 minutes and consider a fluid bolus.”
Why this is the answer
A good recommendation is specific about the request and the time frame. Vague statements leave the provider unsure how urgent the problem is.
Answer
C · “I would like you to see him within 15 minutes and consider a fluid bolus.”
16.Prioritization & delegation
Answer: B · Cardiac tamponade
Why this is the answer
Hypotension, distended neck veins and muffled heart sounds suggest fluid compressing the heart. A sudden stop in chest drain output can mean clots are trapping blood around the heart; this is an emergency.