NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
30 kg2 mg/kg/day4× per dayD = ? mg

A patient weighs 30 kg. The prescribed dose is 2 mg/kg per day, given in 4 equal doses. How many milligrams D are given per dose?

30 kg2 mg/kg/day4× per day
D = mg
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 4150 units of a drug that comes as 5000 units/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

4150 units5000 units/mL
V = mL
3.IV infusion ratesMedium
60 gtt/mL50 mL/h? gtt/min

An infusion is ordered at 50 mL/h, but no pump is available. It runs by gravity through a giving set of 60 gtt/mL. Find the drip rate R in drops per minute.

50 mL/h60 gtt/mL
R = gtt/min
4.IV infusion ratesHard
100 mg250 mL9 mL/h? mcg/min

An infusion of 100 mg in 250 mL runs at 9 mL/h. How many micrograms per minute D does the patient receive?

100 mg/250 mL9 mL/h
D = mcg/min
5.Pediatric & critical-care dosingMedium
100 units250 mLregular insulin? mL/h6 units/h

Practice exercise (made-up values, not clinical guidance). An infusion contains 100 units of regular insulin in 250 mL. The order is 6 units/h. Find the pump rate R in mL/h. Round to one decimal place.

100 units/250 mL6 units/h
R = mL/h
6.Pediatric & critical-care dosingHard
250 mg250 mLdobutamine7 mL/h55 kg? mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A dobutamine infusion of 250 mg in 250 mL runs at 7 mL/h. The patient weighs 55 kg. What dose D in mcg/kg/min is the patient receiving? Round to one decimal place.

250 mg/250 mL7 mL/h55 kg
D = mcg/kg/min
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftjelly120 mLtea240 mLIV infusion80 mL/h × 8 hIV antibiotic2 × 50 mLurine300 mLurine250 mLurine300 mLurine350 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL.

jelly: 120 mLtea: 240 mLIV infusion: 80 mL/h × 8 hIV antibiotic: 2 × 50 mL
I = mL
8.IV fluids & fluid balanceHard
500 mL→ 100 mL/hstart 19:30ttotal​ = ? h75 mL/h × 3 h

Practice exercise (made-up values, not clinical guidance). A 500 mL infusion starts at 19:30 at 75 mL/h. After 3 hours the rate is changed to 100 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

500 mL75 mL/h · 3 h100 mL/h
t = h
9.Nursing math & unit conversionsMedium
0.85757 mL? mLround to 0.01 mL

Practice exercise (made-up values, not clinical guidance). A dose calculation for a small injection gives 0.85757 mL. The rule in this exercise is that volumes below 1 mL are rounded to the nearest hundredth of a mL. What value x do you record?

0.85757 mL
x = mL
10.Nursing math & unit conversionsHard
2 tsp · 2/day · 5 d? mL1 tsp = 5 mL

Practice exercise (made-up values, not clinical guidance). A prescription reads 2 tsp of an oral suspension every 12 hours for 5 days. Using 1 tsp = 5 mL, how many mL V are needed for the whole course?

2 tspevery 12 hours5 days1 tsp = 5 mL
V = mL

3Solutions

1.Dosage calculations

Answer: D = 15 mg

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Total per day

2·30 = 60 mg

Per dose

D = 60/4 = 15 mg

Answer

D = 15 mg
2.Dosage calculations

Answer: V = 0.83 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Volume

V = 4150/5000 = 0.83 mL

On the syringe

On this 1 mL syringe every small line is 0.01 mL.

Answer

V = 0.83 mL
3.IV infusion rates

Answer: R = 50 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Millilitres per minute

50/60 = 0.8333 mL/min

Drip rate

R = 0.8333·60 = 50 gtt/min

Answer

R = 50 gtt/min

With a microdrip set (60 gtt/mL), gtt/min equals mL/h.

4.IV infusion rates

Answer: D = 60 mcg/min

Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).

Concentration

100000 mcg/250 mL = 400 mcg/mL

Dose per hour

9·400 = 3600 mcg/h

Dose per minute

D = 3600/60 = 60 mcg/min

Answer

D = 60 mcg/min
5.Pediatric & critical-care dosing

Answer: R = 15 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

100/250 = 0.4 units/mL

Pump rate

R = 6/0.4 = 15 mL/h

Answer

R = 15 mL/h
6.Pediatric & critical-care dosing

Answer: D = 2.1 mcg/kg/min

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

250 000/250 = 1000 mcg/mL

Micrograms per minute

7·1000 = 7000 mcg/h
7000/60 = 116.7 mcg/min

Per kilogram

D = 116.7/55 = 2.121 ≈ 2.1 mcg/kg/min

Answer

D = 2.1 mcg/kg/min
7.IV fluids & fluid balance

Answer: I = 1100 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 120 + 240 = 360 mL
IV infusion: 80·8 = 640 mL
IV antibiotic: 2·50 = 100 mL
I = 1100 mL

Answer

I = 1100 mL
8.IV fluids & fluid balance

Answer: t = 5.8 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

75·3 = 225 mL
500 − 225 = 275 mL left

Second part

275/100 = 2.75 h

Total time

t = 3 + 2.75 = 5.75 ≈ 5.8 h

Answer

t = 5.8 h

That is about 5 h 45 min, so the bag runs out at about 01:15.

9.Nursing math & unit conversions

Answer: x = 0.86 mL

Rounding: look at the digit just after the place you round to: 5 or more rounds up, 4 or less leaves the digit as it is. Round only the final answer, never the steps. Typical exam rules: volumes of 1 mL or more to the nearest tenth, volumes below 1 mL to the nearest hundredth, drip rates to whole drops and weights to one decimal place; always follow the rule the question states.

Digit in the hundredths place

0.85757 → 5

Only the next digit decides

0.85757 → 7
7 is 5 or more, so round 5 up.
The digits after it (57) are ignored: round once, never step by step.

Round

x = 0.86 mL

Answer

x = 0.86 mL
10.Nursing math & unit conversions

Answer: V = 100 mL

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Volume per dose

2 tsp = 2·5 = 10 mL

Whole course

V = 10 mL × 2/day × 5 = 100 mL

Answer

V = 100 mL

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