NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 8 kg is prescribed 4 mg/kg of a drug. The stock solution contains 20 mg/mL. Draw up the dose: what volume V do you give?

8 kg4 mg/kg20 mg/mL
V = mL
2.Dosage calculationsHard
100 mg/1 mLV = ? mL

A patient weighs 74.8 lb. The prescription is 1 mg/kg as a single dose, and the stock contains 100 mg in 1 mL. Using 1 kg = 2.2 lb, what volume V do you give?

74.8 lb1 mg/kg100 mg/1 mL1 kg = 2.2 lb
V = mL
3.IV infusion ratesMedium
530 mLleft? mL/h3 h left

1000 mL was ordered over 6 hours. After 3 hours you find that 530 mL is still in the bag, and the order must still finish on time. To what rate R in mL/h must the pump be reset?

1000 mL / 6 hafter 3 h: 530 mL
R = mL/h
4.IV infusion ratesHard
900 mL15 gtt/mL28 gtt/mint = ? h

A drip runs at 28 gtt/min through a set of 15 gtt/mL. There are 900 mL left in the bag. How many hours t until it is empty? Round to one decimal place.

28 gtt/min15 gtt/mL900 mL
t = h
5.Pediatric & critical-care dosingMedium
heparin 1 000 units/mL60 units/kg · 62 kg → V = ? mL

Practice exercise (made-up values, not clinical guidance). A practice protocol calls for a heparin bolus of 60 units/kg for a patient who weighs 62 kg. The vial contains 1 000 units/mL. What volume V do you draw up? Round to one decimal place.

60 units/kg62 kg1 000 units/mL
V = mL
6.Pediatric & critical-care dosingHard
800 mg500 mLdopamine8 mL/h98 kg? mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A dopamine infusion of 800 mg in 500 mL runs at 8 mL/h. The patient weighs 98 kg. What dose D in mcg/kg/min is the patient receiving? Round to one decimal place.

800 mg/500 mL8 mL/h98 kg
D = mcg/kg/min
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftjuice120 mLtea150 mLmilk200 mLice chips120 mLIV infusion60 mL/h × 8 hIV antibiotic1 × 100 mLurine175 mLurine150 mLvomit200 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The patient weighs 48 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

48 kg8 hurine: 175 mLurine: 150 mLvomit: 200 mL
U = mL/kg/h
8.IV fluids & fluid balanceHard
1000 mL300 mL infused75 mL/h13:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 75 mL/h. At 13:00, 300 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL300 mL infused75 mL/h
t = h
9.Nursing math & unit conversionsMedium
12345678910111212:45?12:45 PM2:45 PM12:45 AM11:45 PM

Practice exercise (made-up values, not clinical guidance). A dose is charted at 12:45 (24-hour clock). Which entry is the same time on the 12-hour clock? Click it.

12:45
  1. 112:45 PM
  2. 22:45 PM
  3. 312:45 AM
  4. 411:45 PM
10.Nursing math & unit conversionsHard
15 mcg/min? mg/h1 h = 60 min1 mg = 1000 mcg

Practice exercise (made-up values, not clinical guidance). An infusion delivers 15 mcg/min. Express this dose rate D in mg/h.

15 mcg/min1 h = 60 min1 mg = 1000 mcg
D = mg/h

3Solutions

1.Dosage calculations

Answer: V = 1.6 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 4·8 = 32 mg

Volume

V = 32/20 = 1.6 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 1.6 mL
2.Dosage calculations

Answer: V = 0.34 mL

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Weight in kg

74.8/2.2 = 34 kg

Dose

1·34 = 34 mg

Volume

V = (34/100)·1 = 0.34 mL

Answer

V = 0.34 mL
3.IV infusion rates

Answer: R = 176.7 mL/h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Original rate

1000/6 = 166.7 mL/h

New rate

R = 530/3 = 176.7 mL/h

Answer

R = 176.7 mL/h

Many hospitals allow such an adjustment up to 25% without a new order; check local policy.

4.IV infusion rates

Answer: t = 8 h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

28·60/15 = 112 mL/h

Time left

t = 900/112 = 8.036 ≈ 8 h

Answer

t = 8 h
5.Pediatric & critical-care dosing

Answer: V = 3.7 mL

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units needed

60·62 = 3 720 units

Volume

V = 3720/1000 = 3.72 ≈ 3.7 mL

Answer

V = 3.7 mL
6.Pediatric & critical-care dosing

Answer: D = 2.2 mcg/kg/min

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

800 000/500 = 1600 mcg/mL

Micrograms per minute

8·1600 = 12800 mcg/h
12800/60 = 213.3 mcg/min

Per kilogram

D = 213.3/98 = 2.177 ≈ 2.2 mcg/kg/min

Answer

D = 2.2 mcg/kg/min
7.IV fluids & fluid balance

Answer: U = 0.85 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

175 + 150 = 325 mL

Per kilogram per hour

U = 325/(48·8) = 0.8464 ≈ 0.85 mL/kg/h

Answer

U = 0.85 mL/kg/h
8.IV fluids & fluid balance

Answer: t = 9.3 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 300 = 700 mL

Time

t = 700/75 = 9.333 ≈ 9.3 h

Answer

t = 9.3 h

That is about 9 h 20 min, so the bag runs out at about 22:20.

9.Nursing math & unit conversions

Answer: 12:45 PM

24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.

Convert the hour

12 → 12 PM

Answer

12:45 PM

Answer

12:45 PM
10.Nursing math & unit conversions

Answer: D = 0.9 mg/h

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Set up the chain

D = 15 mcg/min × (60 min/1 h) × (1 mg/1000 mcg)

Calculate

D = 15·60/1000 = 0.9 mg/h

Answer

D = 0.9 mg/h

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