NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 26 kg is prescribed 5 mg/kg of a drug. The stock solution contains 25 mg/mL. Draw up the dose: what volume V do you give?

26 kg5 mg/kg25 mg/mL
V = mL
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 1900 micrograms. The ampoule contains 2 mg/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

1900 mcg2 mg/mL
V = mL
3.IV infusion ratesMedium
V = ?15 gtt/mL50 gtt/min2 h

A drip runs at 50 gtt/min through a set of 15 gtt/mL. How many millilitres V does the patient receive in 2 hours?

50 gtt/min15 gtt/mL2 h
V = mL
4.IV infusion ratesHard
600 mL20 gtt/mL42 gtt/mint = ? h

A drip runs at 42 gtt/min through a set of 20 gtt/mL. There are 600 mL left in the bag. How many hours t until it is empty? Round to one decimal place.

42 gtt/min20 gtt/mL600 mL
t = h
5.Pediatric & critical-care dosingMedium
50 units50 mLregular insulin? mL/h99 kg0.1 units/kg/h

Practice exercise (made-up values, not clinical guidance). An infusion contains 50 units of regular insulin in 50 mL. The order is 0.1 units/kg/h for a patient who weighs 99 kg. Find the pump rate R in mL/h. Round to one decimal place.

50 units/50 mL0.1 units/kg/h99 kg
R = mL/h
6.Pediatric & critical-care dosingHard
500 mg250 mLdobutamine28 mL/h95 kg? mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A dobutamine infusion of 500 mg in 250 mL runs at 28 mL/h. The patient weighs 95 kg. What dose D in mcg/kg/min is the patient receiving? Round to one decimal place.

500 mg/250 mL28 mL/h95 kg
D = mcg/kg/min
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftjuice150 mLsoup150 mLIV infusion60 mL/h × 12 hIV antibiotic1 × 100 mLurine500 mLurine500 mLurine475 mLurine375 mLwound drain110 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL.

juice: 150 mLsoup: 150 mLIV infusion: 60 mL/h × 12 hIV antibiotic: 1 × 100 mL
I = mL
8.IV fluids & fluid balanceHard
1000 mL→ 125 mL/hstart 12:00ttotal​ = ? h120 mL/h × 3 h

Practice exercise (made-up values, not clinical guidance). A 1000 mL infusion starts at 12:00 at 120 mL/h. After 3 hours the rate is changed to 125 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

1000 mL120 mL/h · 3 h125 mL/h
t = h
9.Nursing math & unit conversionsMedium
94969810010210410635363738394041°F°C99.2 °F? °C

Practice exercise (made-up values, not clinical guidance). A patient’s temperature is 99.2 °F. Convert it to degrees Celsius T with °C = (°F − 32) × 5/9. Round to one decimal place.

99.2 °F
T = °C
10.Nursing math & unit conversionsHard
00:0020:5508:50t = ?

Practice exercise (made-up values, not clinical guidance). An infusion starts at 20:55 and finishes at 08:50 the next morning (24-hour clock). How many minutes t did it run?

20:5508:50
t = min

3Solutions

1.Dosage calculations

Answer: V = 5.2 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 5·26 = 130 mg

Volume

V = 130/25 = 5.2 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 5.2 mL
2.Dosage calculations

Answer: V = 0.95 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Same units

2 mg/mL = 2000 mcg/mL

Volume

V = 1900/2000 = 0.95 mL

Answer

V = 0.95 mL
3.IV infusion rates

Answer: V = 400 mL

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

50·60/15 = 200 mL/h

Volume

V = 200·2 = 400 mL

Answer

V = 400 mL
4.IV infusion rates

Answer: t = 4.8 h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

42·60/20 = 126 mL/h

Time left

t = 600/126 = 4.762 ≈ 4.8 h

Answer

t = 4.8 h
5.Pediatric & critical-care dosing

Answer: R = 9.9 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

0.1·99 = 9.9 units/h

Concentration

50/50 = 1 units/mL

Pump rate

R = 9.9/1 = 9.9 mL/h

Answer

R = 9.9 mL/h
6.Pediatric & critical-care dosing

Answer: D = 9.8 mcg/kg/min

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

500 000/250 = 2000 mcg/mL

Micrograms per minute

28·2000 = 56000 mcg/h
56000/60 = 933.3 mcg/min

Per kilogram

D = 933.3/95 = 9.825 ≈ 9.8 mcg/kg/min

Answer

D = 9.8 mcg/kg/min
7.IV fluids & fluid balance

Answer: I = 1120 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 150 + 150 = 300 mL
IV infusion: 60·12 = 720 mL
IV antibiotic: 1·100 = 100 mL
I = 1120 mL

Answer

I = 1120 mL
8.IV fluids & fluid balance

Answer: t = 8.1 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

120·3 = 360 mL
1000 − 360 = 640 mL left

Second part

640/125 = 5.12 h

Total time

t = 3 + 5.12 = 8.12 ≈ 8.1 h

Answer

t = 8.1 h

That is about 8 h 07 min, so the bag runs out at about 20:07.

9.Nursing math & unit conversions

Answer: T = 37.3 °C

Temperature: °C = (°F − 32) × 5/9 and °F = °C × 9/5 + 32. Subtract 32 before you multiply when going from °F, and add 32 after you multiply when going from °C. A quick check: 37 °C is 98.6 °F, and every 1 °C is 1.8 °F.

Subtract 32

99.2 − 32 = 67.2

Multiply by 5/9

T = 67.2·5/9 = 37.33 ≈ 37.3 °C

Answer

T = 37.3 °C
10.Nursing math & unit conversions

Answer: t = 715 min

24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.

Before midnight

20:55 → 24:00 = 185 min

After midnight

00:00 → 08:50 = 530 min

Total

t = 185 + 530 = 715 min

Answer

t = 715 min

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