NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 10 kg is prescribed 2.5 mg/kg of a drug. The stock solution contains 25 mg/mL. Draw up the dose: what volume V do you give?

10 kg2.5 mg/kg25 mg/mL
V = mL
2.Dosage calculationsHard
19 kg101 cmBSA = √(h·w/3600)175 mg/m²D = ? mg

A patient is 101 cm tall and weighs 19 kg. The prescription is 175 mg/m². Using the Mosteller formula BSA = √(height (cm) × weight (kg)/3600), find the dose D in mg.

101 cm19 kg175 mg/m²
D = mg
3.IV infusion ratesMedium
500 mL10 gtt/mL5 h? gtt/min

Infuse 500 mL over 5 hours with a giving set of 10 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

500 mL5 h10 gtt/mL
R = gtt/min
4.IV infusion ratesHard
490 mLleft? mL/h4 h left

1000 mL was ordered over 10 hours. After 6 hours you find that 490 mL is still in the bag, and the order must still finish on time. By what percentage Δ must the original pump rate be increased?

1000 mL / 10 hafter 6 h: 490 mL
Δ = %
5.Pediatric & critical-care dosingMedium
heparin 5 000 units/mL60 units/kg · 99 kg → V = ? mL

Practice exercise (made-up values, not clinical guidance). A practice protocol calls for a heparin bolus of 60 units/kg for a patient who weighs 99 kg. The vial contains 5 000 units/mL. What volume V do you draw up? Round to one decimal place.

60 units/kg99 kg5 000 units/mL
V = mL
6.Pediatric & critical-care dosingHard
800 mg500 mLdopamine? mL/h86 kg6 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dopamine 800 mg in 500 mL. The order is 6 mcg/kg/min for a patient who weighs 86 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

800 mg/500 mL6 mcg/kg/min86 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftsoup180 mLjuice120 mLIV infusion125 mL/h × 8 hIV antibiotic2 × 100 mLurine375 mLurine175 mLurine425 mLurine425 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss).

soup: 180 mLjuice: 120 mLIV infusion: 125 mL/h × 8 hIV antibiotic: 2 × 100 mLurine: 375 mLurine: 175 mLurine: 425 mLurine: 425 mL
B = mL
8.IV fluids & fluid balanceHard
500 mL→ 80 mL/hstart 07:00ttotal​ = ? h100 mL/h × 2 h

Practice exercise (made-up values, not clinical guidance). A 500 mL infusion starts at 07:00 at 100 mL/h. After 2 hours the rate is changed to 80 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

500 mL100 mL/h · 2 h80 mL/h
t = h
9.Nursing math & unit conversionsMedium
0.65314 mL? mLround to 0.01 mL

Practice exercise (made-up values, not clinical guidance). A dose calculation for a small injection gives 0.65314 mL. The rule in this exercise is that volumes below 1 mL are rounded to the nearest hundredth of a mL. What value x do you record?

0.65314 mL
x = mL
10.Nursing math & unit conversionsHard
1½ cups? mL1½ fl oz? mL1 tbsp? mL1 tsp? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes 1½ cups of tea, 1½ fl oz of juice, 1 tbsp of liquid supplement, 1 tsp of cough syrup. Using the equivalents given, find the total oral intake V in mL.

1 cup = 8 fl oz = 240 mL1 fl oz = 30 mL1 tbsp = 15 mL1 tsp = 5 mL
V = mL

3Solutions

1.Dosage calculations

Answer: V = 1 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 2.5·10 = 25 mg

Volume

V = 25/25 = 1 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 1 mL
2.Dosage calculations

Answer: D = 127.8 mg

Body-surface-area dosing: many cytotoxic and some paediatric doses are prescribed per square metre of body surface area: dose (mg) = dose per m² × BSA (m²). The Mosteller formula estimates BSA = √(height (cm) × weight (kg)/3600).

Body surface area

BSA = √(101·19/3600) = √0.5331 = 0.7301 m²

Dose

D = 175·0.7301 = 127.8 mg

Answer

D = 127.8 mg
3.IV infusion rates

Answer: R = 17 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

5·60 = 300 min

Drip rate

R = 500·10/300 = 16.67 ≈ 17 gtt/min

Answer

R = 17 gtt/min

At the bedside you round to the nearest whole drop: 17 gtt/min.

4.IV infusion rates

Answer: Δ = 22.5 %

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Original rate

1000/10 = 100 mL/h

New rate

R = 490/4 = 122.5 mL/h

Percentage change

Δ = (122.5 − 100)/100·100% = 22.5%

Answer

Δ = 22.5%

Many hospitals allow such an adjustment up to 25% without a new order; check local policy.

5.Pediatric & critical-care dosing

Answer: V = 1.2 mL

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units needed

60·99 = 5 940 units

Volume

V = 5940/5000 = 1.188 ≈ 1.2 mL

Answer

V = 1.2 mL
6.Pediatric & critical-care dosing

Answer: R = 19.4 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

800 mg = 800 000 mcg
800 000/500 = 1600 mcg/mL

Dose per minute and per hour

6·86 = 516 mcg/min
516·60 = 30960 mcg/h

Pump rate

R = 30960/1600 = 19.35 ≈ 19.4 mL/h

Answer

R = 19.4 mL/h
7.IV fluids & fluid balance

Answer: B = 100 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 180 + 120 = 300 mL
IV infusion: 125·8 = 1000 mL
IV antibiotic: 2·100 = 200 mL
total intake = 1500 mL

Total output

375 + 175 + 425 + 425 = 1400 mL

Balance

B = 1500 − 1400 = 100 mL

Answer

B = 100 mL

Positive: more fluid went in than came out.

8.IV fluids & fluid balance

Answer: t = 5.8 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

100·2 = 200 mL
500 − 200 = 300 mL left

Second part

300/80 = 3.75 h

Total time

t = 2 + 3.75 = 5.75 ≈ 5.8 h

Answer

t = 5.8 h

That is about 5 h 45 min, so the bag runs out at about 12:45.

9.Nursing math & unit conversions

Answer: x = 0.65 mL

Rounding: look at the digit just after the place you round to: 5 or more rounds up, 4 or less leaves the digit as it is. Round only the final answer, never the steps. Typical exam rules: volumes of 1 mL or more to the nearest tenth, volumes below 1 mL to the nearest hundredth, drip rates to whole drops and weights to one decimal place; always follow the rule the question states.

Digit in the hundredths place

0.65314 → 5

Only the next digit decides

0.65314 → 3
3 is 4 or less, so 5 stays.
The digits after it (14) are ignored: round once, never step by step.

Round

x = 0.65 mL

Answer

x = 0.65 mL
10.Nursing math & unit conversions

Answer: V = 425 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

1½ cups = 1.5·240 = 360 mL
1½ fl oz = 1.5·30 = 45 mL
1 tbsp = 1·15 = 15 mL
1 tsp = 1·5 = 5 mL

Add

V = 360 + 45 + 15 + 5 = 425 mL

Answer

V = 425 mL

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