NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 22 kg is prescribed 20 mg/kg of a drug. The stock solution contains 50 mg/mL. Draw up the dose: what volume V do you give?

22 kg20 mg/kg50 mg/mL
V = mL
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 135 micrograms. The ampoule contains 0.5 mg/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

135 mcg0.5 mg/mL
V = mL
3.IV infusion ratesMedium
1000 mL20 gtt/mL8 h? gtt/min

Infuse 1000 mL over 8 hours with a giving set of 20 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

1000 mL8 h20 gtt/mL
R = gtt/min
4.IV infusion ratesHard
400 mL15 gtt/mL32 gtt/mint = ? h

A drip runs at 32 gtt/min through a set of 15 gtt/mL. There are 400 mL left in the bag. How many hours t until it is empty? Round to one decimal place.

32 gtt/min15 gtt/mL400 mL
t = h
5.Pediatric & critical-care dosingMedium
heparin 1 000 units/mL60 units/kg · 79 kg → V = ? mL

Practice exercise (made-up values, not clinical guidance). A practice protocol calls for a heparin bolus of 60 units/kg for a patient who weighs 79 kg. The vial contains 1 000 units/mL. What volume V do you draw up? Round to one decimal place.

60 units/kg79 kg1 000 units/mL
V = mL
6.Pediatric & critical-care dosingHard
50 mg250 mLnitroglycerin? mL/h64 kg20 mcg/min

Practice exercise (made-up values, not clinical guidance). A patient who weighs 64 kg has an order for nitroglycerin at 20 mcg/min. The bag contains 50 mg in 250 mL. Find the pump rate R in mL/h. Round to one decimal place.

50 mg/250 mL20 mcg/min64 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftwater120 mLjuice100 mLtea240 mLIV infusion80 mL/h × 8 hIV antibiotic2 × 50 mLurine225 mLurine200 mLurine475 mLurine450 mLvomit100 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL.

water: 120 mLjuice: 100 mLtea: 240 mLIV infusion: 80 mL/h × 8 hIV antibiotic: 2 × 50 mL
I = mL
8.IV fluids & fluid balanceHard
1000 mL450 mL infused75 mL/h15:30t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 75 mL/h. At 15:30, 450 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL450 mL infused75 mL/h
t = h
9.Nursing math & unit conversionsMedium
122.1425 kg? kground to 0.1 kg

Practice exercise (made-up values, not clinical guidance). A weight conversion gives 122.1425 kg. The rule in this exercise is that weights are rounded to the nearest tenth of a kilogram. What value x do you record?

122.1425 kg
x = kg
10.Nursing math & unit conversionsHard
00:0022:0507:55t = ?

Practice exercise (made-up values, not clinical guidance). An infusion starts at 22:05 and finishes at 07:55 the next morning (24-hour clock). How many minutes t did it run?

22:0507:55
t = min

3Solutions

1.Dosage calculations

Answer: V = 8.8 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 20·22 = 440 mg

Volume

V = 440/50 = 8.8 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 8.8 mL
2.Dosage calculations

Answer: V = 0.27 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Same units

0.5 mg/mL = 500 mcg/mL

Volume

V = 135/500 = 0.27 mL

Answer

V = 0.27 mL
3.IV infusion rates

Answer: R = 42 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

8·60 = 480 min

Drip rate

R = 1000·20/480 = 41.67 ≈ 42 gtt/min

Answer

R = 42 gtt/min

At the bedside you round to the nearest whole drop: 42 gtt/min.

4.IV infusion rates

Answer: t = 3.1 h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

32·60/15 = 128 mL/h

Time left

t = 400/128 = 3.125 ≈ 3.1 h

Answer

t = 3.1 h
5.Pediatric & critical-care dosing

Answer: V = 4.7 mL

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units needed

60·79 = 4 740 units

Volume

V = 4740/1000 = 4.74 ≈ 4.7 mL

Answer

V = 4.7 mL
6.Pediatric & critical-care dosing

Answer: R = 6 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

50 000/250 = 200 mcg/mL

Dose per hour

The order is per minute for the whole patient, so the weight is not needed.

20·60 = 1200 mcg/h

Pump rate

R = 1200/200 = 6 mL/h

Answer

R = 6 mL/h
7.IV fluids & fluid balance

Answer: I = 1200 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 120 + 100 + 240 = 460 mL
IV infusion: 80·8 = 640 mL
IV antibiotic: 2·50 = 100 mL
I = 1200 mL

Answer

I = 1200 mL
8.IV fluids & fluid balance

Answer: t = 7.3 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 450 = 550 mL

Time

t = 550/75 = 7.333 ≈ 7.3 h

Answer

t = 7.3 h

That is about 7 h 20 min, so the bag runs out at about 22:50.

9.Nursing math & unit conversions

Answer: x = 122.1 kg

Rounding: look at the digit just after the place you round to: 5 or more rounds up, 4 or less leaves the digit as it is. Round only the final answer, never the steps. Typical exam rules: volumes of 1 mL or more to the nearest tenth, volumes below 1 mL to the nearest hundredth, drip rates to whole drops and weights to one decimal place; always follow the rule the question states.

Digit in the tenths place

122.1425 → 1

Only the next digit decides

122.1425 → 4
4 is 4 or less, so 1 stays.
The digits after it (25) are ignored: round once, never step by step.

Round

x = 122.1 kg

Answer

x = 122.1 kg
10.Nursing math & unit conversions

Answer: t = 590 min

24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.

Before midnight

22:05 → 24:00 = 115 min

After midnight

00:00 → 07:55 = 475 min

Total

t = 115 + 475 = 590 min

Answer

t = 590 min

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