NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 24 kg is prescribed 4 mg/kg of a drug. The stock solution contains 10 mg/mL. Draw up the dose: what volume V do you give?

24 kg4 mg/kg10 mg/mL
V = mL
2.Dosage calculationsHard
100 mg/5 mLV = ? mL

A child weighing 10 kg is prescribed 15 mg/kg per dose of an oral suspension that contains 100 mg in 5 mL. What volume V do you give?

10 kg15 mg/kg100 mg/5 mL
V = mL
3.IV infusion ratesMedium
V = ?15 gtt/mL40 gtt/min6 h

A drip runs at 40 gtt/min through a set of 15 gtt/mL. How many millilitres V does the patient receive in 6 hours?

40 gtt/min15 gtt/mL6 h
V = mL
4.IV infusion ratesHard
400 mL20 gtt/mL40 gtt/mint = ? h

A drip runs at 40 gtt/min through a set of 20 gtt/mL. There are 400 mL left in the bag. How many hours t until it is empty? Round to one decimal place.

40 gtt/min20 gtt/mL400 mL
t = h
5.Pediatric & critical-care dosingMedium
12 500 units250 mLheparin? mL/h87 kg14 units/kg/h

Practice exercise (made-up values, not clinical guidance). A bag contains 12 500 units of heparin in 250 mL. The order is 14 units/kg/h for a patient who weighs 87 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

12 500 units/250 mL14 units/kg/h87 kg
R = mL/h
6.Pediatric & critical-care dosingHard
250 mg250 mLdobutamine? mL/h67 kg10 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dobutamine 250 mg in 250 mL. The order is 10 mcg/kg/min for a patient who weighs 67 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

250 mg/250 mL10 mcg/kg/min67 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftjuice120 mLtea200 mLice chips100 mLIV infusion50 mL/h × 8 hIV antibiotic2 × 50 mLurine475 mLurine150 mLurine425 mLurine425 mLwound drain50 mLvomit100 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss). Count ice chips as half their volume.

juice: 120 mLtea: 200 mLice chips: 100 mLIV infusion: 50 mL/h × 8 hIV antibiotic: 2 × 50 mLurine: 475 mLurine: 150 mLurine: 425 mLurine: 425 mLwound drain: 50 mLvomit: 100 mL
B = mL
8.IV fluids & fluid balanceHard
1000 mL250 mL infused75 mL/h11:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 75 mL/h. At 11:00, 250 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL250 mL infused75 mL/h
t = h
9.Nursing math & unit conversionsMedium
14.2399 mL? mLround to 0.1 mL

Practice exercise (made-up values, not clinical guidance). A dose calculation for an injection gives 14.2399 mL. The rule in this exercise is that volumes of 1 mL or more are rounded to the nearest tenth of a mL. What value x do you record?

14.2399 mL
x = mL
10.Nursing math & unit conversionsHard
2 tsp · 3/day · 7 d? × 100 mL1 tsp = 5 mL

Practice exercise (made-up values, not clinical guidance). A prescription reads 2 tsp of an oral suspension three times a day for 7 days. The suspension comes in 100 mL bottles. Using 1 tsp = 5 mL, how many whole bottles N must be supplied so the course is complete?

2 tspthree times a day7 days100 mL1 tsp = 5 mL
N =

3Solutions

1.Dosage calculations

Answer: V = 9.6 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 4·24 = 96 mg

Volume

V = 96/10 = 9.6 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 9.6 mL
2.Dosage calculations

Answer: V = 7.5 mL

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Dose from weight

15·10 = 150 mg

Volume

V = (150/100)·5 = 7.5 mL

Answer

V = 7.5 mL
3.IV infusion rates

Answer: V = 960 mL

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

40·60/15 = 160 mL/h

Volume

V = 160·6 = 960 mL

Answer

V = 960 mL
4.IV infusion rates

Answer: t = 3.3 h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

40·60/20 = 120 mL/h

Time left

t = 400/120 = 3.333 ≈ 3.3 h

Answer

t = 3.3 h
5.Pediatric & critical-care dosing

Answer: R = 24.4 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

14·87 = 1 218 units/h

Concentration

12 500/250 = 50 units/mL

Pump rate

R = 1218/50 = 24.36 ≈ 24.4 mL/h

Answer

R = 24.4 mL/h
6.Pediatric & critical-care dosing

Answer: R = 40.2 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

250 mg = 250 000 mcg
250 000/250 = 1000 mcg/mL

Dose per minute and per hour

10·67 = 670 mcg/min
670·60 = 40200 mcg/h

Pump rate

R = 40200/1000 = 40.2 mL/h

Answer

R = 40.2 mL/h
7.IV fluids & fluid balance

Answer: B = −755 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 120 + 200 = 320 mL
ice chips: 100/2 = 50 mL
IV infusion: 50·8 = 400 mL
IV antibiotic: 2·50 = 100 mL
total intake = 870 mL

Total output

475 + 150 + 425 + 425 + 50 + 100 = 1625 mL

Balance

B = 870 − 1625 = −755 mL

Answer

B = −755 mL

Negative: the patient lost more fluid than went in.

8.IV fluids & fluid balance

Answer: t = 10 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 250 = 750 mL

Time

t = 750/75 = 10 h

Answer

t = 10 h

That is about 10 h 00 min, so the bag runs out at about 21:00.

9.Nursing math & unit conversions

Answer: x = 14.2 mL

Rounding: look at the digit just after the place you round to: 5 or more rounds up, 4 or less leaves the digit as it is. Round only the final answer, never the steps. Typical exam rules: volumes of 1 mL or more to the nearest tenth, volumes below 1 mL to the nearest hundredth, drip rates to whole drops and weights to one decimal place; always follow the rule the question states.

Digit in the tenths place

14.2399 → 2

Only the next digit decides

14.2399 → 3
3 is 4 or less, so 2 stays.
The digits after it (99) are ignored: round once, never step by step.

Round

x = 14.2 mL

Answer

x = 14.2 mL
10.Nursing math & unit conversions

Answer: N = 3

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Total volume

10 mL × 3 × 7 = 210 mL

Bottles

210/100 = 2.1 → N = 3

Answer

N = 3

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