NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 6 kg is prescribed 15 mg/kg of a drug. The stock solution contains 50 mg/mL. Draw up the dose: what volume V do you give?

6 kg15 mg/kg50 mg/mL
V = mL
2.Dosage calculationsHard
250 mg/5 mLV = ? mL

A patient weighs 52.8 lb. The prescription is 5 mg/kg as a single dose, and the stock contains 250 mg in 5 mL. Using 1 kg = 2.2 lb, what volume V do you give?

52.8 lb5 mg/kg250 mg/5 mL1 kg = 2.2 lb
V = mL
3.IV infusion ratesMedium
1000 mL20 gtt/mL5 h? gtt/min

Infuse 1000 mL over 5 hours with a giving set of 20 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

1000 mL5 h20 gtt/mL
R = gtt/min
4.IV infusion ratesHard
450 mL20 gtt/mL28 gtt/mint = ? h

A drip runs at 28 gtt/min through a set of 20 gtt/mL. There are 450 mL left in the bag. How many hours t until it is empty? Round to one decimal place.

28 gtt/min20 gtt/mL450 mL
t = h
5.Pediatric & critical-care dosingMedium
heparin 1 000 units/mL60 units/kg · 100 kg → V = ? mL

Practice exercise (made-up values, not clinical guidance). A practice protocol calls for a heparin bolus of 60 units/kg for a patient who weighs 100 kg. The vial contains 1 000 units/mL. What volume V do you draw up? Round to one decimal place.

60 units/kg100 kg1 000 units/mL
V = mL
6.Pediatric & critical-care dosingHard
500 mg250 mLdobutamine? mL/h110 kg2.5 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dobutamine 500 mg in 250 mL. The order is 2.5 mcg/kg/min for a patient who weighs 110 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

500 mg/250 mL2.5 mcg/kg/min110 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shifttea240 mLwater300 mLmilk100 mLice chips200 mLIV infusion100 mL/h × 8 hIV antibiotic1 × 50 mLurine250 mLurine375 mLurine325 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL. Count ice chips as half their volume.

tea: 240 mLwater: 300 mLmilk: 100 mLice chips: 200 mLIV infusion: 100 mL/h × 8 hIV antibiotic: 1 × 50 mL
I = mL
8.IV fluids & fluid balanceHard
1000 mL650 mL infused60 mL/h19:30t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 60 mL/h. At 19:30, 650 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL650 mL infused60 mL/h
t = h
9.Nursing math & unit conversionsMedium
1234567891011125:30 AM?17:3006:3004:3005:30

Practice exercise (made-up values, not clinical guidance). A dose is charted at 5:30 AM. Which entry is the same time on the 24-hour clock? Click it.

5:30 AM
  1. 117:30
  2. 206:30
  3. 304:30
  4. 405:30
10.Nursing math & unit conversionsHard
3 tbsp? mL3 fl oz? mL1 cup? mL2½ tsp? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes 3 tbsp of liquid supplement, 3 fl oz of juice, 1 cup of tea, 2½ tsp of cough syrup. Using the equivalents given, find the total oral intake V in mL.

1 tbsp = 15 mL1 fl oz = 30 mL1 cup = 8 fl oz = 240 mL1 tsp = 5 mL
V = mL

3Solutions

1.Dosage calculations

Answer: V = 1.8 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 15·6 = 90 mg

Volume

V = 90/50 = 1.8 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 1.8 mL
2.Dosage calculations

Answer: V = 2.4 mL

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Weight in kg

52.8/2.2 = 24 kg

Dose

5·24 = 120 mg

Volume

V = (120/250)·5 = 2.4 mL

Answer

V = 2.4 mL
3.IV infusion rates

Answer: R = 67 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

5·60 = 300 min

Drip rate

R = 1000·20/300 = 66.67 ≈ 67 gtt/min

Answer

R = 67 gtt/min

At the bedside you round to the nearest whole drop: 67 gtt/min.

4.IV infusion rates

Answer: t = 5.4 h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

28·60/20 = 84 mL/h

Time left

t = 450/84 = 5.357 ≈ 5.4 h

Answer

t = 5.4 h
5.Pediatric & critical-care dosing

Answer: V = 6 mL

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units needed

60·100 = 6 000 units

Volume

V = 6000/1000 = 6 mL

Answer

V = 6 mL
6.Pediatric & critical-care dosing

Answer: R = 8.3 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

500 mg = 500 000 mcg
500 000/250 = 2000 mcg/mL

Dose per minute and per hour

2.5·110 = 275 mcg/min
275·60 = 16500 mcg/h

Pump rate

R = 16500/2000 = 8.25 ≈ 8.3 mL/h

Answer

R = 8.3 mL/h
7.IV fluids & fluid balance

Answer: I = 1590 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 240 + 300 + 100 = 640 mL
ice chips: 200/2 = 100 mL
IV infusion: 100·8 = 800 mL
IV antibiotic: 1·50 = 50 mL
I = 1590 mL

Answer

I = 1590 mL
8.IV fluids & fluid balance

Answer: t = 5.8 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 650 = 350 mL

Time

t = 350/60 = 5.833 ≈ 5.8 h

Answer

t = 5.8 h

That is about 5 h 50 min, so the bag runs out at about 01:20.

9.Nursing math & unit conversions

Answer: 05:30

24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.

Convert the hour

5 AM → 05

Answer

05:30

Answer

05:30
10.Nursing math & unit conversions

Answer: V = 387.5 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

3 tbsp = 3·15 = 45 mL
3 fl oz = 3·30 = 90 mL
1 cup = 1·240 = 240 mL
2½ tsp = 2.5·5 = 12.5 mL

Add

V = 45 + 90 + 240 + 12.5 = 387.5 mL

Answer

V = 387.5 mL

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