NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 12 kg is prescribed 5 mg/kg of a drug. The stock solution contains 50 mg/mL. Draw up the dose: what volume V do you give?

12 kg5 mg/kg50 mg/mL
V = mL
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 6500 units of a drug that comes as 10000 units/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

6500 units10000 units/mL
V = mL
3.IV infusion ratesMedium
V = ?15 gtt/mL30 gtt/min2 h

A drip runs at 30 gtt/min through a set of 15 gtt/mL. How many millilitres V does the patient receive in 2 hours?

30 gtt/min15 gtt/mL2 h
V = mL
4.IV infusion ratesHard
400 mg100 mL30 mL/h? mg/h

A bag contains 400 mg of a drug in 100 mL and runs at 30 mL/h. How many milligrams per hour D does the patient receive?

400 mg/100 mL30 mL/h
D = mg/h
5.Pediatric & critical-care dosingMedium
12 500 units250 mLheparin? mL/h66 kg15 units/kg/h

Practice exercise (made-up values, not clinical guidance). A bag contains 12 500 units of heparin in 250 mL. The order is 15 units/kg/h for a patient who weighs 66 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

12 500 units/250 mL15 units/kg/h66 kg
R = mL/h
6.Pediatric & critical-care dosingHard
250 mg250 mLdobutamine? mL/h65 kg2.5 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dobutamine 250 mg in 250 mL. The order is 2.5 mcg/kg/min for a patient who weighs 65 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

250 mg/250 mL2.5 mcg/kg/min65 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftsoup180 mLjuice200 mLmilk240 mLIV infusion60 mL/h × 12 hIV antibiotic1 × 50 mLurine475 mLurine475 mLvomit100 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The patient weighs 69 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

69 kg12 hurine: 475 mLurine: 475 mLvomit: 100 mL
U = mL/kg/h
8.IV fluids & fluid balanceHard
1000 mL50 mL/hstart 11:3015:00: ? mL

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag was started at 11:30 and runs by pump at 50 mL/h. How many mL V are left in the bag at 15:00?

1000 mL50 mL/h11:30 → 15:00
V = mL
9.Nursing math & unit conversionsMedium
94969810010210410635363738394041°F°C? °F39.5 °C

Practice exercise (made-up values, not clinical guidance). A patient’s temperature is 39.5 °C. Convert it to degrees Fahrenheit T with °F = °C × 9/5 + 32. Round to one decimal place.

39.5 °C
T = °F
10.Nursing math & unit conversionsHard
00:0017:0001:10t = ?

Practice exercise (made-up values, not clinical guidance). An infusion starts at 17:00 and finishes at 01:10 the next morning (24-hour clock). How many minutes t did it run?

17:0001:10
t = min

3Solutions

1.Dosage calculations

Answer: V = 1.2 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 5·12 = 60 mg

Volume

V = 60/50 = 1.2 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 1.2 mL
2.Dosage calculations

Answer: V = 0.65 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Volume

V = 6500/10000 = 0.65 mL

On the syringe

On this 1 mL syringe every small line is 0.01 mL.

Answer

V = 0.65 mL
3.IV infusion rates

Answer: V = 240 mL

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

30·60/15 = 120 mL/h

Volume

V = 120·2 = 240 mL

Answer

V = 240 mL
4.IV infusion rates

Answer: D = 120 mg/h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Concentration

400/100 = 4 mg/mL

Dose rate

D = 4·30 = 120 mg/h

Answer

D = 120 mg/h
5.Pediatric & critical-care dosing

Answer: R = 19.8 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

15·66 = 990 units/h

Concentration

12 500/250 = 50 units/mL

Pump rate

R = 990/50 = 19.8 mL/h

Answer

R = 19.8 mL/h
6.Pediatric & critical-care dosing

Answer: R = 9.8 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

250 mg = 250 000 mcg
250 000/250 = 1000 mcg/mL

Dose per minute and per hour

2.5·65 = 162.5 mcg/min
162.5·60 = 9750 mcg/h

Pump rate

R = 9750/1000 = 9.75 ≈ 9.8 mL/h

Answer

R = 9.8 mL/h
7.IV fluids & fluid balance

Answer: U = 1.15 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

475 + 475 = 950 mL

Per kilogram per hour

U = 950/(69·12) = 1.147 ≈ 1.15 mL/kg/h

Answer

U = 1.15 mL/kg/h
8.IV fluids & fluid balance

Answer: V = 825 mL

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Elapsed time

11:30 → 15:00 = 3.5 h

Volume infused

50·3.5 = 175 mL

Volume left

V = 1000 − 175 = 825 mL

Answer

V = 825 mL
9.Nursing math & unit conversions

Answer: T = 103.1 °F

Temperature: °C = (°F − 32) × 5/9 and °F = °C × 9/5 + 32. Subtract 32 before you multiply when going from °F, and add 32 after you multiply when going from °C. A quick check: 37 °C is 98.6 °F, and every 1 °C is 1.8 °F.

Multiply by 9/5

39.5·9/5 = 71.1

Add 32

T = 71.1 + 32 = 103.1 °F

Answer

T = 103.1 °F
10.Nursing math & unit conversions

Answer: t = 490 min

24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.

Before midnight

17:00 → 24:00 = 420 min

After midnight

00:00 → 01:10 = 70 min

Total

t = 420 + 70 = 490 min

Answer

t = 490 min

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