NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
25 kg15 mg/kg/day3× per dayD = ? mg

A patient weighs 25 kg. The prescribed dose is 15 mg/kg per day, given in 3 equal doses. How many milligrams D are given per dose?

25 kg15 mg/kg/day3× per day
D = mg
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 100 micrograms. The ampoule contains 0.5 mg/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

100 mcg0.5 mg/mL
V = mL
3.IV infusion ratesMedium
V = ?20 gtt/mL25 gtt/min12 h

A drip runs at 25 gtt/min through a set of 20 gtt/mL. How many millilitres V does the patient receive in 12 hours?

25 gtt/min20 gtt/mL12 h
V = mL
4.IV infusion ratesHard
420 mLleft? mL/h4 h left

1000 mL was ordered over 12 hours. After 8 hours you find that 420 mL is still in the bag, and the order must still finish on time. By what percentage Δ must the original pump rate be increased?

1000 mL / 12 hafter 8 h: 420 mL
Δ = %
5.Pediatric & critical-care dosingMedium
100 units100 mLregular insulin7.5 mL/h? units/h

Practice exercise (made-up values, not clinical guidance). An infusion of 100 units of regular insulin in 100 mL runs at 7.5 mL/h. How many units per hour D does the patient receive?

100 units/100 mL7.5 mL/h
D = units/h
6.Pediatric & critical-care dosingHard
250 mg250 mLdobutamine? mL/h81 kg10 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dobutamine 250 mg in 250 mL. The order is 10 mcg/kg/min for a patient who weighs 81 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

250 mg/250 mL10 mcg/kg/min81 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftwater150 mLjelly120 mLjuice200 mLice chips120 mLIV infusion60 mL/h × 8 hIV antibiotic2 × 100 mLurine150 mLurine175 mLurine225 mLvomit100 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The patient weighs 106 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

106 kg8 hurine: 150 mLurine: 175 mLurine: 225 mLvomit: 100 mL
U = mL/kg/h
8.IV fluids & fluid balanceHard
1000 mL350 mL infused120 mL/h06:30t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 120 mL/h. At 06:30, 350 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL350 mL infused120 mL/h
t = h
9.Nursing math & unit conversionsMedium
15.3749 kg? kground to 0.1 kg

Practice exercise (made-up values, not clinical guidance). A weight conversion gives 15.3749 kg. The rule in this exercise is that weights are rounded to the nearest tenth of a kilogram. What value x do you record?

15.3749 kg
x = kg
10.Nursing math & unit conversionsHard
1 tsp · 3/day · 7 d? mL1 tsp = 5 mL

Practice exercise (made-up values, not clinical guidance). A prescription reads 1 tsp of an oral suspension three times a day for 7 days. Using 1 tsp = 5 mL, how many mL V are needed for the whole course?

1 tspthree times a day7 days1 tsp = 5 mL
V = mL

3Solutions

1.Dosage calculations

Answer: D = 125 mg

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Total per day

15·25 = 375 mg

Per dose

D = 375/3 = 125 mg

Answer

D = 125 mg
2.Dosage calculations

Answer: V = 0.2 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Same units

0.5 mg/mL = 500 mcg/mL

Volume

V = 100/500 = 0.2 mL

Answer

V = 0.2 mL
3.IV infusion rates

Answer: V = 900 mL

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

25·60/20 = 75 mL/h

Volume

V = 75·12 = 900 mL

Answer

V = 900 mL
4.IV infusion rates

Answer: Δ = 26 %

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Original rate

1000/12 = 83.33 mL/h

New rate

R = 420/4 = 105 mL/h

Percentage change

Δ = (105 − 83.33)/83.33·100% = 26%

Answer

Δ = 26%

This is more than a 25% increase: most hospitals require you to contact the prescriber instead of catching up, and to assess the patient for fluid overload.

5.Pediatric & critical-care dosing

Answer: D = 7.5 units/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

100/100 = 1 units/mL

Units per hour

D = 7.5·1 = 7.5 units/h

Answer

D = 7.5 units/h
6.Pediatric & critical-care dosing

Answer: R = 48.6 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

250 mg = 250 000 mcg
250 000/250 = 1000 mcg/mL

Dose per minute and per hour

10·81 = 810 mcg/min
810·60 = 48600 mcg/h

Pump rate

R = 48600/1000 = 48.6 mL/h

Answer

R = 48.6 mL/h
7.IV fluids & fluid balance

Answer: U = 0.65 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

150 + 175 + 225 = 550 mL

Per kilogram per hour

U = 550/(106·8) = 0.6486 ≈ 0.65 mL/kg/h

Answer

U = 0.65 mL/kg/h
8.IV fluids & fluid balance

Answer: t = 5.4 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 350 = 650 mL

Time

t = 650/120 = 5.417 ≈ 5.4 h

Answer

t = 5.4 h

That is about 5 h 25 min, so the bag runs out at about 11:55.

9.Nursing math & unit conversions

Answer: x = 15.4 kg

Rounding: look at the digit just after the place you round to: 5 or more rounds up, 4 or less leaves the digit as it is. Round only the final answer, never the steps. Typical exam rules: volumes of 1 mL or more to the nearest tenth, volumes below 1 mL to the nearest hundredth, drip rates to whole drops and weights to one decimal place; always follow the rule the question states.

Digit in the tenths place

15.3749 → 3

Only the next digit decides

15.3749 → 7
7 is 5 or more, so round 3 up.
The digits after it (49) are ignored: round once, never step by step.

Round

x = 15.4 kg

Answer

x = 15.4 kg
10.Nursing math & unit conversions

Answer: V = 105 mL

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Volume per dose

1 tsp = 1·5 = 5 mL

Whole course

V = 5 mL × 3/day × 7 = 105 mL

Answer

V = 105 mL

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