NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
15 kg2 mg/kg/day2× per dayD = ? mg

A patient weighs 15 kg. The prescribed dose is 2 mg/kg per day, given in 2 equal doses. How many milligrams D are given per dose?

15 kg2 mg/kg/day2× per day
D = mg
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 360 micrograms. The ampoule contains 1 mg/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

360 mcg1 mg/mL
V = mL
3.IV infusion ratesMedium
500 mL60 gtt/mL8 h? gtt/min

Infuse 500 mL over 8 hours with a giving set of 60 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

500 mL8 h60 gtt/mL
R = gtt/min
4.IV infusion ratesHard
1000 mg500 mL60 gtt/mL40 mg/h? gtt/min

1000 mg of a drug is diluted in 500 mL and given by gravity through a set of 60 gtt/mL. The order is 40 mg per hour. Find the drip rate R in drops per minute.

1000 mg/500 mL40 mg/h60 gtt/mL
R = gtt/min
5.Pediatric & critical-care dosingMedium
250 units250 mLregular insulin15 mL/h? units/h

Practice exercise (made-up values, not clinical guidance). An infusion of 250 units of regular insulin in 250 mL runs at 15 mL/h. How many units per hour D does the patient receive?

250 units/250 mL15 mL/h
D = units/h
6.Pediatric & critical-care dosingHard
4 mg250 mLnorepinephrine? mL/h98 kg10 mcg/min

Practice exercise (made-up values, not clinical guidance). A patient who weighs 98 kg has an order for norepinephrine at 10 mcg/min. The bag contains 4 mg in 250 mL. Find the pump rate R in mL/h. Round to one decimal place.

4 mg/250 mL10 mcg/min98 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftjelly100 mLwater250 mLIV infusion60 mL/h × 8 hIV antibiotic2 × 50 mLurine400 mLurine450 mLurine200 mLwound drain130 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL.

jelly: 100 mLwater: 250 mLIV infusion: 60 mL/h × 8 hIV antibiotic: 2 × 50 mL
I = mL
8.IV fluids & fluid balanceHard
1000 mL→ 60 mL/hstart 17:30ttotal​ = ? h150 mL/h × 4 h

Practice exercise (made-up values, not clinical guidance). A 1000 mL infusion starts at 17:30 at 150 mL/h. After 4 hours the rate is changed to 60 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

1000 mL150 mL/h · 4 h60 mL/h
t = h
9.Nursing math & unit conversionsMedium
94969810010210410635363738394041°F°C100.5 °F? °C

Practice exercise (made-up values, not clinical guidance). A patient’s temperature is 100.5 °F. Convert it to degrees Celsius T with °C = (°F − 32) × 5/9. Round to one decimal place.

100.5 °F
T = °C
10.Nursing math & unit conversionsHard
2 tsp? mL4 tbsp? mL1 cup? mL6 fl oz? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes 2 tsp of cough syrup, 4 tbsp of liquid supplement, 1 cup of tea, 6 fl oz of juice. Using the equivalents given, find the total oral intake V in mL.

1 tsp = 5 mL1 tbsp = 15 mL1 cup = 8 fl oz = 240 mL1 fl oz = 30 mL
V = mL

3Solutions

1.Dosage calculations

Answer: D = 15 mg

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Total per day

2·15 = 30 mg

Per dose

D = 30/2 = 15 mg

Answer

D = 15 mg
2.Dosage calculations

Answer: V = 0.36 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Same units

1 mg/mL = 1000 mcg/mL

Volume

V = 360/1000 = 0.36 mL

Answer

V = 0.36 mL
3.IV infusion rates

Answer: R = 63 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

8·60 = 480 min

Drip rate

R = 500·60/480 = 62.5 ≈ 63 gtt/min

Answer

R = 63 gtt/min

At the bedside you round to the nearest whole drop: 63 gtt/min.

4.IV infusion rates

Answer: R = 20 gtt/min

Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).

Concentration

1000/500 = 2 mg/mL

Volume per hour

40/2 = 20 mL/h

Drip rate

R = 20·60/60 = 20 gtt/min

Answer

R = 20 gtt/min
5.Pediatric & critical-care dosing

Answer: D = 15 units/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

250/250 = 1 units/mL

Units per hour

D = 15·1 = 15 units/h

Answer

D = 15 units/h
6.Pediatric & critical-care dosing

Answer: R = 37.5 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

4 000/250 = 16 mcg/mL

Dose per hour

The order is per minute for the whole patient, so the weight is not needed.

10·60 = 600 mcg/h

Pump rate

R = 600/16 = 37.5 mL/h

Answer

R = 37.5 mL/h
7.IV fluids & fluid balance

Answer: I = 930 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 100 + 250 = 350 mL
IV infusion: 60·8 = 480 mL
IV antibiotic: 2·50 = 100 mL
I = 930 mL

Answer

I = 930 mL
8.IV fluids & fluid balance

Answer: t = 10.7 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

150·4 = 600 mL
1000 − 600 = 400 mL left

Second part

400/60 = 6.667 h

Total time

t = 4 + 6.667 = 10.67 ≈ 10.7 h

Answer

t = 10.7 h

That is about 10 h 40 min, so the bag runs out at about 04:10.

9.Nursing math & unit conversions

Answer: T = 38.1 °C

Temperature: °C = (°F − 32) × 5/9 and °F = °C × 9/5 + 32. Subtract 32 before you multiply when going from °F, and add 32 after you multiply when going from °C. A quick check: 37 °C is 98.6 °F, and every 1 °C is 1.8 °F.

Subtract 32

100.5 − 32 = 68.5

Multiply by 5/9

T = 68.5·5/9 = 38.06 ≈ 38.1 °C

Answer

T = 38.1 °C
10.Nursing math & unit conversions

Answer: V = 490 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

2 tsp = 2·5 = 10 mL
4 tbsp = 4·15 = 60 mL
1 cup = 1·240 = 240 mL
6 fl oz = 6·30 = 180 mL

Add

V = 10 + 60 + 240 + 180 = 490 mL

Answer

V = 490 mL

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