NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
90 kg2 mg/kgD = ? mg

A patient weighs 90 kg and is prescribed 2 mg/kg as a single dose. Find the dose D in mg.

90 kg2 mg/kg
D = mg
2.Dosage calculationsHard
120 mg/5 mLV = ? mL

A child weighing 16 kg is prescribed 20 mg/kg per dose of an oral suspension that contains 120 mg in 5 mL. What volume V do you give? Round to one decimal place.

16 kg20 mg/kg120 mg/5 mL
V = mL
3.IV infusion ratesMedium
500 mL10 gtt/mL2 h? gtt/min

Infuse 500 mL over 2 hours with a giving set of 10 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

500 mL2 h10 gtt/mL
R = gtt/min
4.IV infusion ratesHard
240 mLleft? mL/h4 h left

500 mL was ordered over 10 hours. After 6 hours you find that 240 mL is still in the bag, and the order must still finish on time. By what percentage Δ must the original pump rate be increased?

500 mL / 10 hafter 6 h: 240 mL
Δ = %
5.Pediatric & critical-care dosingMedium
heparin 5 000 units/mL60 units/kg · 58 kg → V = ? mL

Practice exercise (made-up values, not clinical guidance). A practice protocol calls for a heparin bolus of 60 units/kg for a patient who weighs 58 kg. The vial contains 5 000 units/mL. What volume V do you draw up? Round to two decimal places.

60 units/kg58 kg5 000 units/mL
V = mL
6.Pediatric & critical-care dosingHard
25 mg250 mLnitroglycerin? mL/h79 kg10 mcg/min

Practice exercise (made-up values, not clinical guidance). A patient who weighs 79 kg has an order for nitroglycerin at 10 mcg/min. The bag contains 25 mg in 250 mL. Find the pump rate R in mL/h. Round to one decimal place.

25 mg/250 mL10 mcg/min79 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftjuice120 mLwater200 mLIV infusion75 mL/h × 12 hIV antibiotic1 × 50 mLurine375 mLurine300 mLurine175 mLurine325 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss).

juice: 120 mLwater: 200 mLIV infusion: 75 mL/h × 12 hIV antibiotic: 1 × 50 mLurine: 375 mLurine: 300 mLurine: 175 mLurine: 325 mL
B = mL
8.IV fluids & fluid balanceHard
1000 mL→ 80 mL/hstart 11:30ttotal​ = ? h150 mL/h × 3 h

Practice exercise (made-up values, not clinical guidance). A 1000 mL infusion starts at 11:30 at 150 mL/h. After 3 hours the rate is changed to 80 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

1000 mL150 mL/h · 3 h80 mL/h
t = h
9.Nursing math & unit conversionsMedium
94969810010210410635363738394041°F°C? °F37.3 °C

Practice exercise (made-up values, not clinical guidance). A patient’s temperature is 37.3 °C. Convert it to degrees Fahrenheit T with °F = °C × 9/5 + 32. Round to one decimal place.

37.3 °C
T = °F
10.Nursing math & unit conversionsHard
1 tbsp · 4/day · 5 d? mL1 tbsp = 15 mL

Practice exercise (made-up values, not clinical guidance). A prescription reads 1 tbsp of an oral suspension every 6 hours for 5 days. Using 1 tbsp = 15 mL, how many mL V are needed for the whole course?

1 tbspevery 6 hours5 days1 tbsp = 15 mL
V = mL

3Solutions

1.Dosage calculations

Answer: D = 180 mg

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Dose

2·90 = 180 mg

Answer

D = 180 mg
2.Dosage calculations

Answer: V = 13.3 mL

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Dose from weight

20·16 = 320 mg

Volume

V = (320/120)·5 = 13.33 ≈ 13.3 mL

Answer

V = 13.3 mL
3.IV infusion rates

Answer: R = 42 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

2·60 = 120 min

Drip rate

R = 500·10/120 = 41.67 ≈ 42 gtt/min

Answer

R = 42 gtt/min

At the bedside you round to the nearest whole drop: 42 gtt/min.

4.IV infusion rates

Answer: Δ = 20 %

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Original rate

500/10 = 50 mL/h

New rate

R = 240/4 = 60 mL/h

Percentage change

Δ = (60 − 50)/50·100% = 20%

Answer

Δ = 20%

Many hospitals allow such an adjustment up to 25% without a new order; check local policy.

5.Pediatric & critical-care dosing

Answer: V = 0.7 mL

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units needed

60·58 = 3 480 units

Volume

V = 3480/5000 = 0.696 ≈ 0.7 mL

Answer

V = 0.7 mL
6.Pediatric & critical-care dosing

Answer: R = 6 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

25 000/250 = 100 mcg/mL

Dose per hour

The order is per minute for the whole patient, so the weight is not needed.

10·60 = 600 mcg/h

Pump rate

R = 600/100 = 6 mL/h

Answer

R = 6 mL/h
7.IV fluids & fluid balance

Answer: B = 95 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 120 + 200 = 320 mL
IV infusion: 75·12 = 900 mL
IV antibiotic: 1·50 = 50 mL
total intake = 1270 mL

Total output

375 + 300 + 175 + 325 = 1175 mL

Balance

B = 1270 − 1175 = 95 mL

Answer

B = 95 mL

Positive: more fluid went in than came out.

8.IV fluids & fluid balance

Answer: t = 9.9 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

150·3 = 450 mL
1000 − 450 = 550 mL left

Second part

550/80 = 6.875 h

Total time

t = 3 + 6.875 = 9.875 ≈ 9.9 h

Answer

t = 9.9 h

That is about 9 h 53 min, so the bag runs out at about 21:23.

9.Nursing math & unit conversions

Answer: T = 99.1 °F

Temperature: °C = (°F − 32) × 5/9 and °F = °C × 9/5 + 32. Subtract 32 before you multiply when going from °F, and add 32 after you multiply when going from °C. A quick check: 37 °C is 98.6 °F, and every 1 °C is 1.8 °F.

Multiply by 9/5

37.3·9/5 = 67.14

Add 32

T = 67.14 + 32 = 99.14 ≈ 99.1 °F

Answer

T = 99.1 °F
10.Nursing math & unit conversions

Answer: V = 300 mL

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Volume per dose

1 tbsp = 1·15 = 15 mL

Whole course

V = 15 mL × 4/day × 5 = 300 mL

Answer

V = 300 mL

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