NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
27 kgBSA = 0.91 m²175 mg/m²D = ? mg

A patient weighing 27 kg has a body surface area of 0.91 m². The prescription is 175 mg/m². Find the dose D in mg.

27 kgBSA = 0.91 m²175 mg/m²
D = mg
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 3100 units of a drug that comes as 5000 units/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

3100 units5000 units/mL
V = mL
3.IV infusion ratesMedium
500 mL60 gtt/mL12 h? gtt/min

Infuse 500 mL over 12 hours with a giving set of 60 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

500 mL12 h60 gtt/mL
R = gtt/min
4.IV infusion ratesHard
1000 mg250 mL15 gtt/mL80 mg/h? gtt/min

1000 mg of a drug is diluted in 250 mL and given by gravity through a set of 15 gtt/mL. The order is 80 mg per hour. Find the drip rate R in drops per minute.

1000 mg/250 mL80 mg/h15 gtt/mL
R = gtt/min
5.Pediatric & critical-care dosingMedium
50 units50 mLregular insulin? mL/h92 kg0.05 units/kg/h

Practice exercise (made-up values, not clinical guidance). An infusion contains 50 units of regular insulin in 50 mL. The order is 0.05 units/kg/h for a patient who weighs 92 kg. Find the pump rate R in mL/h. Round to one decimal place.

50 units/50 mL0.05 units/kg/h92 kg
R = mL/h
6.Pediatric & critical-care dosingHard
500 mg250 mLdobutamine? mL/h99 kg10 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dobutamine 500 mg in 250 mL. The order is 10 mcg/kg/min for a patient who weighs 99 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

500 mg/250 mL10 mcg/kg/min99 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftmilk200 mLsoup200 mLIV infusion75 mL/h × 12 hIV antibiotic1 × 100 mLurine500 mLurine300 mLurine175 mLvomit200 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL.

milk: 200 mLsoup: 200 mLIV infusion: 75 mL/h × 12 hIV antibiotic: 1 × 100 mL
I = mL
8.IV fluids & fluid balanceHard
500 mL250 mL infused75 mL/h18:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 500 mL bag runs by pump at 75 mL/h. At 18:00, 250 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

500 mL250 mL infused75 mL/h
t = h
9.Nursing math & unit conversionsMedium
6 lb 5 oz? kg1 lb = 16 oz1 kg = 2.2 lb

Practice exercise (made-up values, not clinical guidance). A newborn weighs 6 lb 5 oz. Using 1 lb = 16 oz and 1 kg = 2.2 lb, find the weight m in kilograms. Round to two decimal places.

6 lb 5 oz1 lb = 16 oz1 kg = 2.2 lb
m = kg
10.Nursing math & unit conversionsHard
2.5 mcg/kg/min? mg/h85 kg1 h = 60 min1 mg = 1000 mcg

Practice exercise (made-up values, not clinical guidance). An order reads 2.5 mcg/kg/min for a patient who weighs 85 kg. Express the dose rate D in mg/h. Round to two decimal places.

2.5 mcg/kg/min85 kg
D = mg/h

3Solutions

1.Dosage calculations

Answer: D = 159.3 mg

Body-surface-area dosing: many cytotoxic and some paediatric doses are prescribed per square metre of body surface area: dose (mg) = dose per m² × BSA (m²). The Mosteller formula estimates BSA = √(height (cm) × weight (kg)/3600).

Dose

D = 175·0.91 = 159.3 mg

Answer

D = 159.3 mg
2.Dosage calculations

Answer: V = 0.62 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Volume

V = 3100/5000 = 0.62 mL

On the syringe

On this 1 mL syringe every small line is 0.01 mL.

Answer

V = 0.62 mL
3.IV infusion rates

Answer: R = 42 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

12·60 = 720 min

Drip rate

R = 500·60/720 = 41.67 ≈ 42 gtt/min

Answer

R = 42 gtt/min

At the bedside you round to the nearest whole drop: 42 gtt/min.

4.IV infusion rates

Answer: R = 5 gtt/min

Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).

Concentration

1000/250 = 4 mg/mL

Volume per hour

80/4 = 20 mL/h

Drip rate

R = 20·15/60 = 5 gtt/min

Answer

R = 5 gtt/min
5.Pediatric & critical-care dosing

Answer: R = 4.6 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

0.05·92 = 4.6 units/h

Concentration

50/50 = 1 units/mL

Pump rate

R = 4.6/1 = 4.6 mL/h

Answer

R = 4.6 mL/h
6.Pediatric & critical-care dosing

Answer: R = 29.7 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

500 mg = 500 000 mcg
500 000/250 = 2000 mcg/mL

Dose per minute and per hour

10·99 = 990 mcg/min
990·60 = 59400 mcg/h

Pump rate

R = 59400/2000 = 29.7 mL/h

Answer

R = 29.7 mL/h
7.IV fluids & fluid balance

Answer: I = 1400 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 200 + 200 = 400 mL
IV infusion: 75·12 = 900 mL
IV antibiotic: 1·100 = 100 mL
I = 1400 mL

Answer

I = 1400 mL
8.IV fluids & fluid balance

Answer: t = 3.3 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

500 − 250 = 250 mL

Time

t = 250/75 = 3.333 ≈ 3.3 h

Answer

t = 3.3 h

That is about 3 h 20 min, so the bag runs out at about 21:20.

9.Nursing math & unit conversions

Answer: m = 2.87 kg

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Ounces to pounds

5 oz/16 = 0.3125 lb
6 + 0.3125 = 6.313 lb

Pounds to kilograms

m = 6.313/2.2 = 2.869 ≈ 2.87 kg

Answer

m = 2.87 kg
10.Nursing math & unit conversions

Answer: D = 12.75 mg/h

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Set up the chain

D = 2.5 mcg/kg/min × 85 kg × (60 min/1 h) × (1 mg/1000 mcg)

Calculate

D = 2.5·85·60/1000 = 12.75 mg/h

Answer

D = 12.75 mg/h

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